429 research outputs found
Erratum: a synonymous variant in GCK gene as a cause of gestational diabetes mellitus (diabetes mellitus. 2019;22(2). Doi: 10.14341/dm9938)
No full textAn erratum on «A synonymous variant in GCK gene as a cause of gestational diabetes mellitus» by Natalya A. Zubkova, Petr M. Rubtsov, Liudmila I. Ibragimova, Nina A. Makretskaya, Evgeny V. Vasiliev, Vasily M. Petrov, Anatoly N. Tiulpakov (2019). Diabetes mellitus. 22(2). doi: 10.14341/DM9938An error was made in the list of authors: Fatima F. Burumkulova was not indicated as author of this article. The correct list of authors: Natalya A. Zubkova, Petr M. Rubtsov, Fatima F. Burumkulova, Liudmila I. Ibragimova, Nina A. Makretskaya, Evgeny V. Vasiliev, Vasily M. Petrov, Anatoly N. Tiulpakov.The editorial board apologize for this error and state that this does not change the scientific conclusions of the article in any way.The original article has been updated
Mutations within the transcription factor PROP1 are rare in a cohort of patients with sporadic combined pituitary hormone deficiency (CPHD)
No full textThe definitive version is available at www.blackwell-synergy.comObjective Mutations within the pituitary-specific paired-like homeobox gene PROP1 have been described in 50–100% of patients with familial combined pituitary hormone deficiency (CPHD). We screened a cohort of sporadic (n = 189) and familial (n = 44) patients with hypopituitarism (153 CPHD and 80 isolated hormone deficiencies) for mutations within the coding sequence of PROP1. Design and patients Patients with congenital hypopituitarism were recruited from the London Centre for Paediatric Endocrinology as well as several national and international centres. The pituitary phenotype ranged from isolated growth hormone deficiency (IGHD) to panhypopituitarism. Clinical data, including endocrine and neuro-radiological studies were obtained from patient records, and DNA was collected and screened for mutations within PROP1 using PCR and single-stranded conformation polymorphism (SSCP) analysis. Positive results on SSCP were sequenced directly. Results The prevalence of PROP1 mutations in unselected sporadic cases of hypopituitarism was lower (1·1%) than in familial cases (29·5%). PROP1 mutations can be associated with a highly variable phenotype, and both pituitary hypoplasia and pituitary hyperplasia. We describe the waxing and waning of a pituitary mass over 20 months in association with a PROP1 mutation that is predicted to lead to complete loss of function. Additionally, we have identified a possible founder mutation in CPHD patients from the Indian subcontinent. Conclusions PROP1 mutations are rare in sporadic cases of CPHD, although the prevalence rises if there is a positive family history or if the patients are carefully selected with respect to the endocrine and neuroradiological phenotype. There is considerable phenotypic variability in families with the same mutation, indicating the role of other genetic or environmental factors on phenotypic expression. Finally, the pituitary enlargement that is observed in patients with PROP1 mutations can wax and wane in size before eventual involution.James P. G. Turton, Ameeta Mehta, Jamal Raza, Kathryn S. Woods, Tiulpakov, Anatoly,Joseph Cassar, Paul Q. Thomas, Marumudi Eunice, Ariachery C Ammini, Pierre M. Bouloux, Jerzy Starzyk, Peter C. Hindmarsh and Mehul T. Dattan
Clinical Outcomes and Complications of Pituitary Blastoma
No full textThis is a pre-copyedited, author-produced version of an article accepted for publication in
Journal of Clinical Endocrinology & Metabolism, following peer review. The version of record: Anthony P Y Liu, Megan M Kelsey, Nelly Sabbaghian, Sung-Hye Park, Cheri L Deal, Adam J Esbenshade, Oswald Ploner, Andrew Peet, Heidi Traunecker, Yomna H E Ahmed, Margaret Zacharin, Anatoly Tiulpakov, Anastasia M Lapshina, Andrew W Walter, Pinaki Dutta, Ashutosh Rai, Márta Korbonits, Leanne de Kock, Kim E Nichols, William D Foulkes, John R Priest, Clinical Outcomes and Complications of Pituitary Blastoma, The Journal of Clinical Endocrinology & Metabolism, , dgaa857, https://doi.org/10.1210/clinem/dgaa857 is available online at: https://doi.org/10.1210/clinem/dgaa85
Anatoly Kuznetsov, Author of Babi Yar: The History of the Book and the Fate of the Author
No full textThis Introduction to the special issue devoted to Anatoly Kuznetsov, author of Babi Yar: A Document in the Form of a Novel, dwells on the different aspects of the book’s importance, surveys the life of the author as intertwined with the history of this book, suggests a way of reading his other work in the light of Babi Yar, and notes the contributions of the articles collected in this issue
The Absurdity of Reality in the Novel of Anatoly Korolev «Byt Boschom» («To be Bosch»)
No full textThe article is devoted to the research of the controversial novel’s poetics of the modern prose writer Anatoly Korolev, the representative of the frontier aesthetics between realism and postmodernism. The author uses various discourses to interpret an absurdity in the novel «Byt Boschom» («To be Bosch»): narration about reality, text in text, metatext. The meaning of the discourses’ combination is represented in the article. Studying the absurdity in the novel allows to see existential problems revealed in this writing
The Absurdity of Reality in the Novel of Anatoly Korolev «Byt Boschom» («To be Bosch»)
No full textThe article is devoted to the research of the controversial novel’s poetics of the modern prose writer Anatoly Korolev, the representative of the frontier aesthetics between realism and postmodernism. The author uses various discourses to interpret an absurdity in the novel «Byt Boschom» («To be Bosch»): narration about reality, text in text, metatext. The meaning of the discourses’ combination is represented in the article. Studying the absurdity in the novel allows to see existential problems revealed in this writing
Nasledie «Sidora Karpovicha» v sovremennoj pesennoj kul'ture
No full textThe article analyzes the transformation of the Russian folk song “Dear
Sir Sidor Karpovich”, studied by V. N. Toporov in 1979. This text was a
prison game depicting a funeral rite and having a function of initiation,
but re cently it has become a popular song and lost its minor mood. At the
same time, the protagonist (Sidor Karpovich) loses his name and becomes
a secondary character. The main role is taken by his wife, Lyubka, called
by the epithet “gray dove”. The plot of the song is based on twists and turns of her life after the death of her husband. Analyzing the image of the dove in poetry and, in particular, in prison lyrics, as well as looking at possible influences of other popular songs, the author proposes possible reasons for such a transformation
Anatoly Vasiliev’s Theatre. Semiology of Continuity and the Way to a New Type of Theatrical System
No full textIntroduction. The article provides a general description of Anatoly Vasiliev’s theatrical method, discussing the essence of methodological and philosophical breakthroughs in the future of Russian and world theaters, and, in this context, the continuity of the main tenets of Stanislavsky’s system.Methodology and sources. The article compares two theatrical concepts, two methodological, philosophical, and historical approaches of Russian and World Theatres: Stanislavski’s system and Vasiliev’s method. It determines the semiology of continuity and features of a new approach to the development of dramatic art.Results and discussion. The article highlights the elements of the Stanislavsky system present in Anatoly Vasiliev’s method, aiming to derive an algorithm for utilizing new opportunities based on established systems and techniques for training modern actors. The article's conclusions are drawn from five years of experience (since 1988) with the Vasiliev method, gained through direct contact with the master while collaborating on texts by Plato, Oscar Wilde, Fyodor Dostoevsky, William Faulkner, Thomas Mann, Erasmus of Rotterdam, and Alexander Pushkin. As the article relies on introspective research followed by epistemological analysis, it maintains a subjective nature. It is the outcome of the author’s experience working within the Anatoly Vasiliev’ s School of Dramatic Art at the GITIS acting and directing course (1988–1993), and years of observation of the method’s evolution in working with Vasiliev's students, students of theater universities, and professional actors both in Russia and abroad.Conclusion. The article does not claim to precisely represent Vasiliev’s ideas and thoughts but rather reflects the author’s journey through the rehearsal process in Vasiliev’s theater, acknowledging the internal changes experienced by the author as an actor, director, and individual within the method. It abstains from making value judgments regarding the Stanislavsky system and Vasiliev’s method, instead highlighting the most distinctive features of the theatrical method, elucidating its philosophy, and emphasizing the unity between the Stanislavsky and Vasiliev systems
La prose de Minaev : phénomène d'altérité « dirigée »
No full textMinaev's prose is a literature of manipulation. The author seems to dissect the world of glamour and success to dispute mass-culture, to denounce the new rich, the jet set - all those whom he calls « the soulless ». The writer claims to offer the diary of a new Pechorin, a present-day Byronic hero. The story, however, is not meant to show a character but to send the readers an ideological message which differs little from official discourse. Aiming at commercial success, many of Minaev's novels are bestsellers - the author tries to represent a false « other » comprised of the current power's admirers, who are presented as a minority. The support given to the writer by the Kremlin-directed media and the conjunction of Minaev's thesis with the main points of propaganda seem to suggest that his prose might be part of a large-scale ideological project.Tokmakov Anatoly. La prose de Minaev : phénomène d'altérité « dirigée ». In: Revue Russe n°33, 2009. D’autres Russies. Altérité, diversité et complexité dans la Russie d' aujourd’hui. pp. 159-169
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