105,145 research outputs found

    MY DAY: JOSEPH H. TIMKO

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    Controlled longitudinal emittance blow-up using band-limited phase noise in CERN PSB

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    Controlled longitudinal emittance blow-up (from 1 eVs to 1.4 eVs) for LHC beams in the CERN PS Booster is currently achievied using sinusoidal phase modulation of a dedicated high-harmonic RF system. In 2021, after the LHC injectors upgrade, 3 eVs should be extracted to the PS. Even if the current method may satisfy the new requirements, it relies on low-power level RF improvements. In this paper another method of blow-up was considered, that is the injection of band-limited phase noise in the main RF system (h=1), never tried in PSB but already used in CERN SPS and LHC, under different conditions (longer cycles). This technique, which lowers the peak line density and therefore the impact of intensity effects in the PSB and the PS, can also be complementary to the present method. The longitudinal space charge, dominant in the PSB, causes significant synchrotron frequency shifts with intensity, and its effect should be taken into account. Another complication arises from the interaction of the phase loop with the injected noise, since both act on the RF phase. All these elements were studied in simulations of the PSB cycle with the BLonD code, and the required blow-up was achieved

    The Relevance and Challenges of an Economic Evaluation of Florida's 4-H Program

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    FE753, a 4-page fact sheet by Alfonso Flores-Lagunes and Troy Timko, describes the 4-H program and the importance of economic evaluation of its impact, provides a primer on economic evaluation of programs, and lays out a research roadmap for accumulating the data necessary for an economic evaluation of the Florida 4-H program. Includes references. Published by the UF Department of Food and Resource Economics, October 2008

    Benchmarking the Beam Longitudinal Dynamics Code BLOND

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    The relatively recent Beam Longitudinal Dynamics code BLonD has already been applied to a wide range of studies for all present CERN synchrotrons. Its application area ranges from studies of RF manipulations, over single and multi-bunch interactions with impedance, to the action of feedback loops and RF noise. In this paper, we present benchmarks and comparisons with measurements, theory, or other codes, which have increased greatly the trust in the code. Tests related to bunch-to-bucket transfer, feedback loops, diffusion due to noise injection, as well as collective effects, are presented

    CERN PS Booster longitudinal dynamics simulations for the post-LS2 scenario

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    The CERN PS Booster is the first synchrotron in the LHC proton injection chain, it currently accelerates particles from 50 MeV to 1.4 GeV kinetic energy. Several upgrades foreseen by the LHC Injectors Upgrade Program will allow the beam to be accelerated from 160 MeV to 2 GeV after Long Shutdown 2 in 2021. The present RF systems will be replaced by a new one, based on Finemet technology. These and other improvements will help to increase the LHC luminosity by a factor of ten. In order to study beam stability in the longitudinal plane simulations have been performed with the CERN BLonD code, using an accurate longitudinal impedance model and a reliable estimation of the longitudinal space charge. Particular attention has been dedicated to the three main features that currently let the beam go stably through the ramp: Double RF operation in bunch-lengthening mode to reduce the transverse space charge tune spread, exploitation of feedback loops to damp dipole oscillations, and controlled longitudinal emittance blow-up. RF phase noise injection has been considered to study if it could complement or substitute the currently used method based on sinusoidal phase modulation

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    DNA sequence of the araBAD-araC controlling region in Salmonella typhimurium LT2

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    The araB and araC genes of Salmonella typhimurium have been cloned onto the plasmid pBR322. Restriction analysis and subcloning of restriction fragments localized these genes to a 4.4 kb DNA fragment. Complementation analysis revealed that the cloned araB and araC genes from S. typhimurium complemented araB and araC mutant strains of escherichia coli. Conversely, cloned araB and araC genes from E. coli complemented araB and araC mutant strains of Escherichia coli. Conversely, cloned araB and araC genes from E. coli complemented araB and ara C mutant strains of S. typhimurium. The DNA sequence was determined for the S. typhimurium araB and araC controlling region and for the initially translated portions of these genes. The nucleotide sequence of the araB promoter was 87% homologous with the same region in E. coli and contained no deletions or insertions relative to the E. coli sequence. The presumed AUG codon corresponding to the amino terminus of the S. typhimurium araC protein was in the same location as in E. coli. There was, however, considerable divergence for the E. coli sequence preceding the translation start site. The nucleotide sequence of the initial 237 bp in the open reading frame of the S. typhimurium araC gene was 78% homologous with the same sequence in E. coli. By comparison, the amino acid sequence for this region was 91% conserved

    Effect of probiotics on the fecal microflora after radiotherapy: A pilot study

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    Background and Aim : The development of gastrointestinal symptoms following pelvic radiotherapy depends on morphological and functional modifications of the intestinal epithelium after radiation. The aim of this study was to evaluate and compare the effects of preventive administration of the preparation ′′5′′ Strain Dophilus and Hylak on the fecal microflora after radiotherapy in patients during radiotherapy. Materials and Methods : Fourteen patients were randomly selected and subdivided into two groups: The first group was administered ′′5′′ Strain Dophilus (L Group) and the second group was administered Hylak (H Group). Radiation was delivered by a Cobalt 60 unit by using the four field box technique. The doses were divided into 2 Gy per day over 5 to 7 weeks to give the total cumulative dose of 50 Gy (2 Gy/day). High risk patients (e.g., patients with prostate cancer), received dosage 65 67 Gy (2 Gy/day). Results : Both experimental and clinical studies have shown that probiotics can effectively modulate intestinal inflammation by altering the composition and the metabolic and functional properties of gut indigenous flora. Conclusions : Many bacteria were found to be sensitive to irradiation. It would be necessary to check the possible effects of cytostatics on bacteria in larger studies

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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