1,127 research outputs found

    Narrenbegräbnis : groteske Bilder / Heinz Zander. Hrsg. von Renate Hartleb

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    NARRENBEGRÄBNIS : GROTESKE BILDER / HEINZ ZANDER. HRSG. VON RENATE HARTLEB Narrenbegräbnis : groteske Bilder / Heinz Zander. Hrsg. von Renate Hartleb (1) Cover (1) Vortitelblatt (10) Titelseite (12) Vorspiel (13) Zu Gedichten und Stücken von Bertolt Brecht (21) Von Doktor Faustus und der Höllen (33) Zu Thomas Manns Romanen Zauberberg und Doktor Faustus (39) Die Festung (53) Gespräche am schwarzen Tisch - eine Studierstubenapokalypse (59) Capriccios: Groteske Tiere, seltsame Begegnungen (81) Frühe Geschichte(n) (113) Nachwort (137) Anhang (143) Inhalt (145

    Bildrepresentationer och bildanalys - replik till Thomas Roth

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    A reply to Thomas Roth, on the interpretation of photographs as historical sources

    Understanding Rhetoric: A Guide to Writing by Elizabeth Losh, Jonathan Alexander, Kevin Cannon, and Zander Cannon [Book Review]

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    The authors of Understanding Rhetoric utilize the comics medium to present writing concepts for first-year composition courses and beyond. The title is a nod to the foundational comics theory treatise by Scott McCloud, Understanding Comics, in which the animated author explores how comics make meaning through image and text. Like McCloud, Understanding Rhetoric’s authors explain rhetoric and writing through didactic content that directly addresses the reader. Losh, Alexander, Cannon, and Cannon take form as characters Liz, Jonathan, Kevin, and Zander in the textbook as they engage students and instructors alike through compelling narrative, humor, visual metaphors, thoughtful examples, and authentic author voices

    mRNA quality control is bypassed for immediate export of stress-responsive transcripts

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    Cells grow well only in a narrow range of physiological conditions. Surviving extreme conditions requires the instantaneous expression of chaperones that help to overcome stressful situations. To ensure the preferential synthesis of these heat-shock proteins, cells inhibit transcription, pre-mRNA processing and nuclear export of non-heat-shock transcripts, while stress-specific mRNAs are exclusively exported and translated1. How cells manage the selective retention of regular transcripts and the simultaneous rapid export of heat-shock mRNAs is largely unknown. In Saccharomyces cerevisiae, the shuttling RNA adaptor proteins Npl3, Gbp2, Hrb1 and Nab2 are loaded co-transcriptionally onto growing pre-mRNAs. For nuclear export, they recruit the export-receptor heterodimer Mex67-Mtr2 (TAP-p15 in humans)(2). Here we show that cellular stress induces the dissociation of Mex67 and its adaptor proteins from regular mRNAs to prevent general mRNA export. At the same time, heat-shock mRNAs are rapidly exported in association with Mex67, without the need for adapters. The immediate co-transcriptional loading of Mex67 onto heat-shock mRNAs involves Hsf1, a heat-shock transcription factor that binds to heat-shock-promoter elements in stress-responsive genes. An important difference between the export modes is that adaptor-protein-bound mRNAs undergo quality control, whereas stress-specific transcripts do not. In fact, regular mRNAs are converted into uncontrolled stress-responsive transcripts if expressed under the control of a heat-shock promoter, suggesting that whether an mRNA undergoes quality control is encrypted therein. Under normal conditions, Mex67 adaptor proteins are recruited for RNA surveillance, with only quality-controlled mRNAs allowed to associate with Mex67 and leave the nucleus. Thus, at the cost of error-free mRNA formation, heat-shock mRNAs are exported and translated without delay, allowing cells to survive extreme situations.Deutsche Forschungsgemeinschaft; [SFB860

    Bildrepresentationer och bildanalys - replik till Thomas Roth

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    A reply to Thomas Roth, on the interpretation of photographs as historical sources

    Influence of Arm Motion on Spatio-temporal Gait Parameters and on Force Data

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    Computational models of walking are not often coherent with experimental design. Although the upper extremities have an active role in human gait, their swing is often neglected or restricted in contrast with the experiments where the subjects are asked to walk freely. The purpose of this study is to assess differences on gait parameters and force data, comparing five arm swing patterns during walking. Motion analysis was performed on six healthy males, using a 10 cameras capture system and two AMTI force plates. Stride time and length, step time and length as well as ground reaction forces and free vertical moment were compared among groups. Results included no statistically difference (p> 0.05) for the gait parameters and the ground reaction forces. However, the main influence of the arm swing was found on the free vertical moment induced by lower limb swing to counterbalance trunk torque. In fact, restraining arms from swinging caused an increase of peak magnitude in the vertical toque between foot and ground. This suggested that although the arms have a little effect on the sagittal and frontal plane, their contribution is relevant in the transversal one. Therefore, an agreement between experiment-modelling is required, especially when upper body inverse dynamic problems are investigated

    (Recension av) Anders Ekström & Sverker Sörlin, Alltings mått : humanistisk kunskap i framtidens samhälle och Tomas Forser & Thomas Karlsohn (red.), Till vilken nytta? : en bok om humanioras möjligheter

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    Recension av Anders Ekström & Sverker Sörlin, Alltings mått : humanistisk kunskap i framtidens samhälle och Tomas Forser & Thomas Karlsohn (red.), Till vilken nytta? : en bok om humanioras möjligheter

    (Recension av) Anders Ekström & Sverker Sörlin, Alltings mått : humanistisk kunskap i framtidens samhälle och Tomas Forser & Thomas Karlsohn (red.), Till vilken nytta? : en bok om humanioras möjligheter

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    Recension av Anders Ekström & Sverker Sörlin, Alltings mått : humanistisk kunskap i framtidens samhälle och Tomas Forser & Thomas Karlsohn (red.), Till vilken nytta? : en bok om humanioras möjligheter

    Evaluation einer arbeitsprozessorientierten IT-Weiterbildung: "IT-Spezialisten"

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    Mit der Einführung der "Arbeitsprozessorientierten" (APO) Weiterbildung im IT-Bereich, haben sich neue Formen der Kenntnisvermittlung, des Coaching und der gesamten Betreuung der Teilnehmer herausgebildet. Gemeinsam mit der lokalen Industrie- und Handelskammer (IHK) hat der Autor 2004, mit dem "Erfurter Modell" einen ersten methodischen Ansatz zur Umsetzung der APO IT-Weiterbildung in der Ebene der "IT-Spezialisten" entwickelt. Als Forschungsgegenstand nimmt der Autor das "Erfurter Modell". Durch eine Evaluation werden Untersuchungen zu Optimierungsmöglichkeiten durchgeführt, die einerseits die Sinnfälligkeit und andererseits die Wirksamkeit der APO IT-Weiterbildung betreffen. Ergänzend wird daraus ein neuer Fragebogen für weitere Trendanalysen entwickelt. Methodisch bedient der Autor sich einer Vorstudie, basierend auf Interviews, um Leitfragen für die Fragebogen der angeschlossenen Hauptstudie abzuleiten. Für eine eingehende Beurteilung wird eine zeitversetzte externe Studie (SCHUBERT 2011) als "follow-up" herangezogen und nach den erarbeiteten Kriterien ausgewertet. Anschließend werden die Ergebnisse verglichen. Über drei Aggregationsstufen (mittlere Merkmalsausprägung bzw. Zustimmungsgrad > Indikator > Leitfrage) wird eine Struktur vorgegeben, die anschließend mittels Datenerhebung geprüft wird. Als einheitliches Verfahren der Strukturprüfung verschiedener Merkmale wird die Kreuztabellierung und Kontingenzanalyse herangezogen. Die Auswertung umfasst neben der Entwicklung des neuen Fragebogens auch Kernaussagen zur Optimierung der APO IT-Weiterbildung nach dem "Erfurter Modell". Auffällig zeigt die Auswertung Potenzial in der Beratung, dem Coaching, der Organisation sowie der Verzahnung von Theorie und Praxis. Diese Erkenntnis ist bedeutsam, denn sie impliziert, dass der Kontakt zur Praxis und die Integration des Unternehmens sehr stark den Abschluss und den Geschäftserfolg des Unternehmens beeinflussen.With the introduction of "work-process-oriented" (WPO) further training in the IT sector, new forms of imparting knowledge, coaching and the overall supervision of participants have emerged. Together with the local Chamber of Industry and Commerce (CIC), the author developed an initial methodical approach to the implementation of WPO further IT training at the level of "IT specialists" in 2004 with the "Erfurter model". The author takes the "Erfurter model" as his object of research. Analyses of possibilities for optimization are implemented by means of an evaluation, on the one hand concerning the manifestness and on the other the effectiveness of WPO further IT training. This is then developed into a new questionnaire for further trend analyses. Methodically, the author draws on a preliminary study, based on interviews, in order to derive central questions for the questionnaire of the associated main study. For a detailed assessment, a time-shifted external study (SCHUBERT 2011) is drawn on as a "follow-up", analysed according to criteria of the main study and the results are compared. A structure is given over three aggregation levels (median characteristics value or degree of agreement > indicator > central question), which is then checked by means of data collection. As a consistend method of testing the structure of different characteristics, cross-tabulation and contingency analysis are used. As well as development of the new questionnaire, the analysis includes core statements on optimizing WPO further IT training according to the "Erfurter model". The analysis clearly shows potential in counselling, coaching, organization and the dovetailing of theory and practice. This realization is significant, as it implies that contact to praxis and the integration of the company have a very strong impact on the qualification and the business success of the company

    Letter 25 from Waguih Ghali to Diana Athill on November 24, 1964

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    Letter, 3 pagesPersonal names mentioned in the letter: Brian Moore (author of "An Answer from Limbo"); Herbert Zander; Edda; Kurt; Rolf; Agatha Christie; Detective Hercule Poirot; Fyodor Dostoevsk
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