1,721,460 research outputs found
Why do people use instant messaging and social networking apps? An investigation from Italian mobile app users
Corporate social responsibility embeddedness through a social network analysis: The case of an Italian multiutility company
To gain substantial benefits, corporate social responsibility (CSR) needs to be embedded within an organization. Through a social network analysis, this study analyzes to what extent an Italian multiutility company, strategically committed to sustainability, integrates social and environmental issues in its strategy, operations, and routines. The paper aims to answer the following two questions: (a) How can an investigation of the level of information exchange help in identifying whether CSR is embedded or peripheral in a company?; (b) how can an investigation of the role of the CSR department help in identifying whether CSR is embedded or peripheral in a company? The study reveals the frequency and density of information exchange regarding social and environmental issues among 67 business units as well as highlighting the real role played by the CSR department. This research contributes to the current debate on CSR embeddedness by showing how an exploration of internal social networks reveals the extent to which CSR is integrated within strategy, operations, and routines. It also provides useful suggestions for managers on ways to improve the level of integration
ADPKD current management and ongoing trials
Among the diseases that require renal replacement therapy (RRT), ADPKD is the fourth for incidence and prevalence. In Italy, there are at least 32,000 patients affected by ADPKD, of which about 2900 in dialysis. The pure costs of dialysis treatment for the Italian National Health Service can be conservatively estimated at 87 million euros per year. Even a modest slowdown in the evolution of the disease would obtain an important result in terms of reduction of health expenditure. In recent years, many new or repurposed drugs have been evaluated in clinical trials for ADPKD. In this review we will mainly focus on advanced stage clinical trials (phase 2 and 3). We have grouped these studies according to the molecular pathway addressed by the experimental drug or the therapeutic strategy. More than 10 years after the start of the first Phase III clinical trials in ADPKD, the first drug active in slowing disease progression is finally available. It cannot be considered a goal but only the beginning of a journey because of the significant side effects and the high cost of Tolvaptan. An exuberant basic research activity in the field, together with the large number of ongoing protocols, keep the nephrologists and their patients positive with regard to the discovery of new and better therapies in a not-too-distant future. © 2019, Italian Society of Nephrology
Dalla cultura nel distretto alla cultura del distretto: una esperienza universitaria in atto
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
