2,156 research outputs found

    Itinerari paesaggistici nel Lazio. La ferrovia Velletri - Terracina, un progetto di rigenerazione dall'interno al mare.

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    Landscape paths in Lazio Region. The Velletri-Terracina railway, a regeneration project from the inland to the coastland. The Rome-Velletri-Terracina line connected the lower Lazio coast to Rome, simplified and increased commercial traffic and the movement of the inhabitants of the province to the capital, networking a series of smaller towns that were first completely isolated. In 1958, the Velletri – Priverno section was officially abolished and in 2012, the service to Terracina was interrupted due to a landslide along the line. The experimentation for the reuse and revitalization of this railway is therefore aimed at the construction of a historical-environmental itinerary, which, through the railway route, enhances the local naturalistic and cultural heritage, integrating the resources and investments available to promote the fruition of the territory beyond the summer season and beyond the bathing activity. A territory whose landscapes, although heterogeneous in their natural and geographical characteristics, are the expression and testimony of a common identity and historical-cultural heritage. The Castelli Romani, the Agro Romano and Pontino, the internal areas as well as the coastal ones, were the scene of profound transformations related to the reclamation works of the Agro Pontino. A territorial system consisting of the sea, the coastal lakes, the Selva di Terracina, the many archaeological pre-existences in which the historical and cultural matrix is characterized by being a land conquered by man, colonized and planned to enhance its productive and agricultural vocation. A feature that has conditioned the belonging and the link between the population and its context, which deserves to be told by following the footprints that remain visible in the very conformation of the territory, in the design of the fields, of the reclamation channels, in the urban morphology of the crossed historic centers

    Game@school. La sperimentazione di un gioco di ruolo per la didattica delle Scienze Integrate

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    Il contributo presenta i primi risultati della sperimentazione di un seriuos game (SG) per l'apprendimento delle STEM in due classi prime (53 studenti di 14-15 anni) di un istituto di istruzione superiore. Sono stati somministrati questionari sulle conoscenze in entrata e in uscita e sul gradimento del gioco. Per quanto riguarda le conoscenze, i risultati del test mostrano un lieve miglioramento delle stesse, passando dal 47% al 53% di risposte corrette. Per ciò che concerne il gradimento del gioco e la percezione dell’apprendimento in relazione ad esso, il 64% dei ragazzi afferma si aver gradito il gioco, il 70% che giocare è più coinvolgente della lezione tradizionale; il 64% pensa di aver imparato giocando e il 68% di aver imparato in modo più divertente, sebbene alcuni studenti abbiano poi mostrato di preferire la lezione classica nella quale non è loro richiesto di assumere responsabilità

    Il Piccolo Tempio di Monte Sant’Angelo a Terracina: nuove ricerche

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    The excavations at the so-called Piccolo Tempio at Monte Sant’Angelo in Terracina were conducted by Ludwig-Maximilians-University Munich in the years 2019–2021. The activities focused on the temple building and its terrace in the western slope of the mountain. The aim of the project is to determine the construction date and to reconstruct the Hellenistic sanctuary for the first time in research history. Thanks to the findings in the construction layers related to the erection of the substructure of the temple platform, the decorations and building technique can be dated to the first two decades 2nd century B.C.E. The complex included a U-shaped cryptoporticus, rich decorated pavements and wall decorations in the First Pompeian Style. During the 2020 excavations the foundation walls of a rectangular temple building were found on the upper part of the platform. It can be reconstructed as a temple building with a cella and two lateral alae. Contrary to the traditional interpretation of the building, both the terrace and the temple face the ancient city of Terracina and the via Appia, and not the sea.L’Università Ludwig Maximilian di Monaco di Baviera ha condotto dal 2019 al 2021 scavi dell’area del cosiddetto Piccolo Tempio, sul pendio occidentale del monte. Le ricerche si sono concentrate sull’edificio sacro e sul suo sistema a terrazze. Scopo del progetto è determinare la cronologia del complesso e ricostruire le varie caratteristiche per la prima volta nella storia degli studi. I materiali rinvenuti nei livelli relativi alle fondazioni delle sostruzioni ad est, insieme allo studio della decorazione e della tecnica edilizia, fanno ipotizzare che il santuario a terrazze sia stato costruito nei primi decenni del II secolo a.C. Il livello inferiore si articola intorno a un criptoportico a forma di »U« e presenta pavimenti decorati e una decorazione pittorica in Primo Stile Pompeiano. Durante la campagna di scavi 2020, nella parte superiore della piattaforma sono state portate in luce le fondazioni di un edificio templare rettangolare, ricostruibile con una pianta a cella trasversale con alae laterali. In contrasto con l’interpretazione tradizionale, il tempio e la sua terrazza non si affacciano in direzione del mare ma verso la Via Appia e l’antico centro di Terracina

    "The love that made hell, paradise." Ouida re-writing the Paolo and Francesca theme in Held in Bondage

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    The bestselling Victorian author Ouida reveals in her novels, and, in particular, Held in Bondage, an extraordinary knowledge od Dante, by using characters and themes from the Commedia. The Paolo and Francesca theme actually constitutes part of the plot of the novel and is to be found in many of her other works, short stories and non-fiction writing

    Gastro-Resistant Microparticles Produced by Spray-Drying as Controlled Release Systems for Liposoluble Vitamins

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    In the present study, gastro-resistant microparticles (MPs) were produced using the spray-drying technique as controlled-release systems for some model liposoluble vitamins, including retinyl-palmitate, retinyl-acetate, β-carotene, cholecalciferol and α-tocopherol. The gastroprotective action of three different gastro-resistant excipients, the anionic methacrylic copolymer (Eudraguard(®®) Biotic, E1207), the cellulose acetate phthalate (CAP) and whey proteins (WPs), was compared. The latter was used to produce a novel delivery system manufactured with only food-derived components, such as milk, and showed several improvements over the two synthetic gastro-resistant agents. Scanning electron microscopy (SEM) images showed a quite homogeneous spherical shape of all microparticle batches, with an average diameter between 7 and 15 μm. FTIR analysis was used to evaluate the effective incorporation of vitamins within the microparticles and the absence of any degradation to the components of the formulation. The comparison graphs of differential scanning calorimetry (DSC) confirmed that the spray drying technique generates a solid in which the physical interactions between the excipients and the vitamins are very strong. Release studies showed a prominent pH-controlled release and partially a delayed-release profile. Ex vivo permeation studies of retinyl palmitate, retinyl acetate and α-tocopherol revealed greater transmucosal permeation capacity for microparticles produced with the WPs and milk

    Tempio di Giove Anxur

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    In un nuovo progetto di scavo diretto da ricercatori tedeschi e italiani (LMU /TMU/Unibo), gli archeologi hanno scoperto prove che suggeriscono che Terracina sia stato il sito del primo tempio ellenistico della regione e un importante insediamento monastico nel medioevo. In alto, sopra l'antica città di Tarracina (oggi Terracina) a sud di Roma, si trova un santuario a terrazze di grandi dimensioni che includeva, probabilmente tre diverse aree templari. Gli edifici offrivano un ampio prospetto sul porto da un lato e dall’altro sulla via Appia, il collegamento più importante della città con Roma. Francesca Diosono, Paul Scheding ed Enrico Cirelli, nel corso di un progetto di scavo che si prevede durerà tre anni, concentreranno la loro attenzione principalmente sul cosiddetto ‘Piccolo Tempio’ e su altre aree dell’insediamento. Ora è stato possibile ricostruire la sua esatta estensione e la sua cronologia al II secolo a.C. Questo lo rende la più antica struttura ellenistica di questo tipo nel Lazio, e forse il primissimo tempio a terrazze della regione. Il tempio stesso e Monte Sant'Angelo, il colle su cui fu eretto, un tempo erano riservati a diversi tipi di cerimonie religiose. Gli scavi hanno confermato che la facciata del tempio era orientata, non verso il porto, ma verso la via Appia e la città sottostante. Al santuario è associato un numero insolitamente elevato di cisterne, riutilizzate e rinforzate dai monaci nell'alto medioevo. Gli scavi hanno anche portato alla luce tracce di un insediamento preromano che risale al VII o forse addirittura al IX secolo a.C. Anche chi ha vissuto qui prima della costruzione del tempio è ancora sconosciuto. Fonti letterarie risalenti al VI secolo aC attestano la presenza dei Volsci nella zona, ma queste popolazioni non sono state associate in modo definitivo ad alcun ritrovamento archeologico della zona. Ulteriori lavori nei prossimi due anni potranno aiutare a chiarire come si sviluppò il Santuario di Monte Sant'Angelo prima e dopo la conquista della regione da parte dei Romani e la forma del Monastero verso il XIV secol

    HERStory Makers 2023: Francesca Fotheringham

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    Francesca Fotheringham is a postdoctoral research associate at the University of Edinburgh studying educational psychology with a focus on neurodiversity. She took part in HERStory Makers 2023.What is HERStory Makers?HERStory Makers is a social media competition for female-identifying early career researchers to share their research, their career journeys, and to inspire the next generation. Winners are selected by public vote. HERStory Makers is also part of EXPLORATHON, Scotland's contribution to European Researchers' Night.In 2022-23, EXPLORATHON Francescasupported by the Engineering & Physical Sciences Research Council [grant number EP/X020762/1].Author contributions to contentFrancesca conceived, planned, and recorded the video content. Kirsty Ross edited the video content to insert HERStory Maker credits, added subtitles, and reduce video length to below Twitter/X limit of 2 mins and 20 secs.</p

    Electrosprayed Poly-butyl-succinate microparticles for sustained release of Ciprofloxacin as an antimicrobial delivery system

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    The increasingly complex treatment of bacterial infections, and its relevance in the clinical setting, requires the development of innovative strategies to improve patients' quality of life. In this context, polymeric microparticles represents a versatile drug delivery system (DDS) capable of improving the antibiotics' efficacy in the treatments, by loading drugs while modifying their release profile. In this study we aimed to produce polymeric micro-particles by electrospraying using Poly-Butyl-Succinate (PBS), a biodegradable and biocompatible polyester. This versatile and easy-to-use technique enabled the incorporation of the poorly water-soluble Ciprofloxacin (CPX) into the polymer matrix. CPX is a fluoroquinolone antibiotic, inhibiting bacterial replication and effectively treating various infections. PBS is a well-known water-insoluble polymer with tuneable chemical-physical properties, also used for tissue regeneration and wound healing applications. An ex-vivo permeation study on porcine skin, serving as a model for human skin, was performed to assess potential enhancement in drug permeation. The microparticles were characterized by means of different techniques (SEM-EDX, XRD, ATR-FTIR, DSC), and their degradation rate was tested in DPBS and human plasma. Moreover, the as-produced DDS enabled the sustained release of CPX for several days, which proved effective against S. aureus and P. aeruginosa and also against a reference group of bacteria of skin microbiota often involved in pathological processes that make wounds chronic and difficult to heal. MIC and MBC assays were conducted using different culture media. Effective antibacterial activity was observed, along with inhibition of P. aeruginosa biofilm formation at sub-MIC concentrations

    A Primeira Guerra Civil Mundial

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    Lanfranco Caminiti, Giuseppe Cocco, Andrea Colombo, Piero Despali, Chicco Galmozzi, Elisabetta Michielin, Brunello Mantelli, Stefania Mazzone, Mimmo Sersante, Giordana Terracina, Francesca Veltr
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