171,438 research outputs found

    Analisi del gender gap nelle Università italiane fra il 2021 e il 2020

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    Con il presente studio, attraverso la disamina di diversi indicatori, si è svolta l’analisi in termini di equilibri di genere nelle università italiane statali e non statali, seguendo le linee guida della CRUI e alla pubblicazione dei dati da parte del Ministero dell’Università e della Ricerca e del Consorzio Interuniversitario Cineca. Dall’analisi quantitativa/qualitativa di tutte le componenti in cui si articola il mondo accademico italiano emerge una sempre più apprezzabile presenza del genere fem- minile ma contestualmente anche la persistente esigenza di continuare a porre una attenzione costante sulle questioni di genere. I dati raccolti ed elaborati evidenziano i cambiamenti registrati a distanza di un anno (il focus è passato dall’anno 2020 al 2021), consapevoli, in ogni caso, che le mutazioni avvengono molto lentamente nel tempo e con effetti troppo deboli per poter incidere efficacemente nelle posizioni di ruolo tra uomini e donne

    Impact of offshore gas platforms on the structural and functional biodiversity of nematodes

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    The Mediterranean Sea hosts hundreds of offshore gas platforms, whose activity represents a potential threat to marine ecosystems. Evidence from several studies indicates that nematodes can be highly sensitive to changes in the environmental quality. Here, we investigated the response of nematode assemblages to the presence of offshore gas platforms (located in the central Mediterranean Sea) in terms of spatial heterogeneity, structural and functional diversity. Since the effect of the investigated offshore platforms on macrofaunal assemblages were previously assessed by Terlizzi et al. (2008), the study provided also the opportunity to compare the response of different benthic compartments to the same impact related to fossil fuel extraction on marine environments. The platforms had a significant impact on nematode assemblages up to 1000 m distance from the structure. The effects were evident in term of: a) more homogeneous spatial distribution of nematode assemblages, b) increased trophic diversity of deposit feeders and c) changes in life strategies with an increase of opportunistic species in sediments closer to the platforms. Such effects seemed to be related to the dimension of the platform structures, rather than to chemical pollution or changes in food availability. These findings suggest that the platforms exert a physical alteration of the surrounding environment that is reflected by altered structural and functional traits of nematode biodiversity. The use of nematodes for monitoring the effects of the platforms only partially matched with the results obtained using macrofauna, providing further insights on potential outcomes on the functional response of marine assemblages to fossil fuel extraction

    Sphingosine-1-Phosphate Shapes Healthy Monocytes into An Immunosuppressive Phenotype

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    Background/Aims: The physiological phenotype of individuals can influence and shape reallife phenomena in that it can contribute to the development of specific characteristics that can affect the immune response to specific stimuli. In this study we aimed to understand whether the sphingosine/sphingosine-1-phoshate (S1P) axis can modulate the immunotype of circulating cells. Methods: To pursue this goal, we performed bioinformatic analyses of public datasets. Results: The transcriptomic profile of healthy subjects of GSE192829 dataset identified two clusters with different transcriptional repertoire. Cluster 1 expressed higher levels of enzymes for S1P formation than cluster 0 which was characterized by enzymes that lead to ceramide formation, which represent the opposite metabolic direction. Inference analysis showed that cluster 1 was higher populated by monocytes, CD4 + T and B cells than cluster 0. Of particular interest was the phenotype of the monocytes in cluster 1 which showed an immunosuppressive nature compared to those in cluster 0. The role of S1P signature in healthy PBMCs was confirmed with other dataset analyses, supporting that circulating monocytes positive to the ceramidase, unlike the negative ones, had an immunosuppressive phenotype characterized by hub immunosuppressive markers (i.e. TYROBP, FCER1G, SYK, SIRPA, CSF1R, AIF1, FCGR2A, CLEC7A, LYN, PLCG2, LILRs, HCK, GAB2). This hub genes well discriminated the immunotype of healthy subjects. Conclusion: In conclusion this study highlights that S1P-associated hub markers can be useful to discriminate subjects with pronounced immunosuppression. (c) 2024 The Author(s). Published by Cell Physiol Biochem Press GmbH&Co. K

    Il turismo in Emilia-Romagna: una sintesi delle recenti tendenze

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    The article contains a broad description of the tourist trend in the Emilia-Romagna region during the years 2001-2003. Official Istat data are used to place the regional tourism in the national outline, while data from provincial and regional administration are handled to find the specific characteristics of the phenomenon in the region. The analysis is based on structural indicators (hotels and complementary structures capacity) and flux indicators (arrivals, presences and mean time of stay) with particular reference to guest’s nationality. National and international tourist fluxes are analysed considering the kind of structure used, the kind of tourist resort, destinations and seasonality

    Single solution sphere-decoding algorithm model predictive control for high-current applications

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    This paper presents a Sphere-Decoding algorithm (SDA) Model Predictive Control (MPC) for a parallel-connected H-Bridges Power Supply (PS). The proposed converter topology faces the very high current peaks (tens of kiloamperes) required by Central Solenoid coils of the Divertor Tokamak Test (DTT) facility for nuclear fusion, quite unusual in industry applications. The choice of the control strategy aims at exploiting the very fast transient response of MPC over linear control schemes and the computational burden reduction of SDA. As a result, this approach is able to guarantee a low load current tracking error and an effective current sharing among H-Bridges, thus proper operations for tens of years. In order to implement the SDA-MPC on a FPGA-based control board, fast but characterized by limited memory, the mathematical model of the PS is first introduced and the SDA-MPC procedure is then mathematically modified to find a single optimized solution. This simplification guarantees a remarkable reduction of the computational burden, avoiding the analysis of a set of possibilities, without losing in control effectiveness. Its performances are verified through simulations and experimentally validated with Hardware-In-the-Loop and prototype tests

    Model Predictive Control for Tokamak Central Solenoid Power Supply

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    Power Supply (PS) systems for nuclear fusion coils are particularly challenging because of the very high current amplitude (tens of kiloamperes), quite unusual in industry applications. Moreover, they need to guarantee a proper plasma initiation and its magnetic confinement for tens of years. To face such demanding requirements, with focus on the Central Solenoid PS of the Divertor Tokamak Test (DTT) facility, Voltage Source Converters are currently under investigation. In particular, this paper analyzes a parallel-connected H-Bridges DC-DC converter. The proposed control strategy consists in a Sphere-Decoding Algorithm (SDA) Model Predictive Control (MPC). This choice aims at exploiting the very fast transient response of MPC and the computational burden reduction of SDA. In order to implement the SDA-MPC, the mathematical model of the presented PS is firstly introduced and validated. Afterwards, the SDA-MPC simulation results are shown and its performance is compared with an interleaved control strategy

    Model Predictive Control with Sphere-Decoding Algorithm for parallel-connected H-Bridges

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    This paper presents a Sphere-Decoding algorithm (SDA) Model Predictive Control (MPC) for a parallel-connected H-Bridges Power Supply (PS). The proposed converter topology faces the very high current peaks (tens of kiloamperes) required by Central Solenoid coils of the Divertor Tokamak Test (DTT) facility for nuclear fusion, quite unusual in industry applications. The choice of the control strategy aims at exploiting the very fast transient response of MPC over linear control schemes and the computational burden reduction of SDA. As a result, this approach is able to guarantee a low load current error tracking and an effective current sharing among H-Bridges, thus a proper plasma initiation and its magnetic confinement for tens of years. In order to implement the SDA-MPC, the mathematical model of the presented PS is firstly introduced and validated. Afterwards, the SDA-MPC performances are tested through simulations. Experimental tests are carried out on a Hardware-In-the-Loop test facility

    Current Sharing Control Strategy for parallel-connected H-Bridges DC-DC Converter: Modelling, Analysis and HIL test

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    Power Electronics Converters employed in nuclear fusion applications have been recently assuming a crucial role for reactors' coils power supply systems as they are particularly challenging not only due to the very high current amplitude, but also to guarantee a proper plasma acceleration and its magnetic confinement for tens of years. To face such demanding requirements, with focus on the Poloidal Field Power Supplies of the Divertor Tokamak Test (DTT) facility, this paper analyzes a parallel-connected H-Bridges (HBs) DCDC converter characterized by relatively low voltages and very high current ratings (tens of kA), quite unusual in industry applications. A specific mathematical model, including the high frequency disturbances identification, has been pointed out for the first time in literature. A current control strategy, which aims at maximizing the current sharing among all HBs legs, is proposed as well. The simulation results have confirmed the validity of the presented control by keeping the load current error below 0.015% and by correctly balancing each HB leg current. These results have been furtherly validated through a Hardware-in-the-loop test facility
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