20,865 research outputs found
ONDEX - a data integration framework for the life sciences
No full textTaubert J. ONDEX - a data integration framework for the life sciences. Bielefeld (Germany): Bielefeld University; 2011.Over the last decade biological research has changed completely. The reductionism approach of studying only a few biological entities at a time in the past is being replaced by the study of the biological system as a whole today. Systems Biology seeks to understand how complex biological systems work by looking at all parts of biological systems, how they interact with each other and form the complete whole. This process requires that existing biological knowledge (data) is made available to support on the one hand the analysis of experimental results and on the other hand the construction and enrichment of models for Systems Biology.
Effective integration of biological knowledge from databases scattered around the internet and other information resources (for example experimental data) is recognized as a pre-requisite for many aspects of Systems Biology research. However, systems for the integration of biological knowledge have to overcome several challenges. For example, biological data sources may contain similar or overlapping coverage and the user of such systems is faced with the challenge of generating a consensus data set or selecting the "best" data source. Furthermore, there are many technical challenges to data integration, like different access methods to databases, different data formats, different naming conventions and erroneous or missing data.
To address these challenges and enable effective integration of biological knowledge in support of Systems Biology research, the ONDEX system which is presented in this thesis was created. The ONDEX system provides an integrated view across biological data sources with the aim to enable the user to gain a better understanding of biology from integrated knowledge. ONDEX is supported by BBSRC (http://www.bbsrc.ac.uk/) as part of the System Approaches to Biological Research initiative (SABR) and is now mainly being developed at Rothamsted Research, Manchester University and Newcastle University. The first ONDEX prototype was developed at University of Bielefeld.
ONDEX uses a three steps approach to address the outlined challenges, namely import of data from data sources, identifying overlapping or similar data across different data sources and analysis of the resulting integrated datasets to reveal new biological insights. This thesis presents the most interesting aspects of the ONDEX system in more detail; all other parts of the ONDEX system will only be briefly described when appropriate
Oral History Interview: Kenneth Taubert (0411)
No full textBackground; Hiring at UW; Custodial supervisor at Memorial Library; Job responsibilities; Custodial hiring practices; Night shift at Memorial Library; Axe incident; Library administration; Elimination of late night hours; Custodial union; Strike; Retirement
Integrative Bioinformatics: History and Future
No full textChen M, Hofestädt R, Taubert J. Integrative Bioinformatics: History and Future. Journal of integrative bioinformatics. 2019;16(3): 20192001
Jan Kapr's contribution to contemporary music : an essay about a composer and teacher
No full textThis creative project is a treatise on a leading personality of Czechoslovakian musical life, the composer, Jan Kapr. The author discusses the following:1. The complicated development of Kapr's career and work, 2. Kapr's method of organization of musical material in a composition, as described in his book Constants,3. His former and current style which is demonstrated in two of his compositions, Concert Variations, for flute and string orchestra and Testimonies for four solo instruments,4. Two of his recent works, Exercises for Gydli and the Symphony No. 7, Country of Childhood.Thesis (M.A.
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
ELEVEN FACES OF JAN GOGOL, JR.
No full textAuthor Jan Rendl in his thesis attempts to look at the world of ideas and educator Jan
Gogola ml. through the eleven chapters in which each chapter somehow characterizes itself by Jan Gogola ml. and each of them somehow determines its creative ideas of it through the metaphor of a football match when Jan Gogola, with its characters, movies himself a teammate, as well as defensively. It gives goals with their situations as well as occasionally digging his opponents ankles.
Jan Gogola ml. thus embodies one stage of the Department of Documentary Film at FAMU, which often stands at the intersection between teaching activities and Karel Vachek among students who applied by them during their seminars psychological methods that work must be peculiarly associated with the author of the film
Dr. Jan French – Faculty Author Interview
No full textDr. Jan French, Assistant Professor of Anthropology, discusses her new book, Legalizing Identities: Becoming Black or Indian in Brazil’s Northeast, which shows how law can successfully serve as the impetus for the transformation of cultural practices and collective identity
Jan Bernátek - organ works
No full textThis graduation thesis provides a more detailed view on compositoins of Jan Bernátek.The aim is to present this less well-known temporary czech author,who makes use of the organ in the majority of his work
Bibliometrie in der Forschungsevaluation. Zur Konstitution und Funktionslogik wechselseitiger Beobachtung zwischen Wissenschaft und Politik
No full textTaubert NC. Bibliometrie in der Forschungsevaluation. Zur Konstitution und Funktionslogik wechselseitiger Beobachtung zwischen Wissenschaft und Politik. In: Passoth J, Wehner J, eds. Quoten, Kurven und Profile. Zur Vermessung der sozialen Welt. Wiesbaden: Springer VS; 2013: 179-204
The Theological Work of Jan Valerián Jirsík
No full textAnglická anotace The theological work of Jan Valerian Jirsík Jan Hamberger This thesis deals with the theological work of the Czech 19th century author Jan Valerián Jirsík (1798-1883). Its first part consists of an introduction into the Czech historical context of the 19th century and the life of the author. Its second part presents a survey of the literary-theological work of Jirsík in three life phases: the first phase is demarked by his activity as chaplain and vicar, the second phase by his editorial activity for Casopis pro katolické duchovenstvo (trans. Magazine for catholic clergy) and the last phase by his pontifical years in the diocese of Southern Bohemia. His literary work is divided by theme into various periods, shortly described and characterized. The last and major section of this thesis deals with the most comprehensive and renown work of Jan Valerián Jirsík - Populární dogmatika (trans. Popular doctrine). This pivotal work of theologian Jirsík is discussed at large and analyzed by tractate, both apologetic and dogmatic. The conclusion expresses the prevailing character of the entire work of Jirsík and its significance. Key words: Theology Apologetic theology Dogmatic theology Theological literature Catholic Churc
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