262,577 research outputs found

    Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases

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    Psychiatric disorders are frequently encountered in many neurological disorders, such as Alzheimer’s and Parkinson diseases along with epilepsy, migraine, essential tremors, and stroke. The most common comorbid diagnoses in neurological diseases are depression and anxiety disorders along with cognitive impairment. Whether the underlying reason is due to common neurochemical mechanisms or loss of previous functioning level, comorbidities are often overlooked. Various treatment options are available, such as pharmacological treatments, cognitive-behavioral therapy, somatic interventions, or electroconvulsive therapy. However oral antidepressant therapy may have some disadvantages, such as interaction with other medications, low tolerability due to side effects, and low efficiency. Natural compounds of plant origin are extensively researched to find a better and safer alternative treatment. Experimental studies have shown that phytochemicals such as alkaloids, terpenes, flavonoids, phenolic acids as well as lipids have significant potential in in vitro and in vivo models of psychiatric disorders. In this review, various efficacy of natural products in in vitro and in vivo studies on neuroprotective and their roles in psychiatric disorders are examined and their neuro-therapeutic potentials are shed light

    Recent developments in the equality and diversity agenda in the UK: the 'big society' under austerity

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    The UK labour market and society are characterized by a vibrant diversity generated by a combination of factors. These factors include migration associated with the country’s post- colonial legacy and to its more recent membership of the EU. It includes the relatively recent demographic shifts related to feminization of the labour market and with an ageing population. It also includes the increased visibility of religious and sexual minorities and of disabled people. Yet, inequalities and disadvantage continues to persist for members of some demographic groups spanning gender, ethnicity, age, disability and sexuality. Confronting discrimination in UK workplaces, in common with other coutries, has been based on a combination of regulatory pressure, derived from a variety of civil society pressures, and of voluntary measures introduced by employers, based upon business- case arguments about the potential benefits of promoting a diverse workforce representative of the social demographic characteristics of the local labour market and customer base. The equilibrium of this balance has not developed evenly and incrementally, however. As Dickens (2007) notes, there has never been a consensus over the extent of what is desirable with regards to equality and diversity, nor the means by which this consensus should best be achieved,The equilibrium that UK equality and diversity at work appeared to have settled at, has been disrupted as a consequence of the global financial crisis after 2008 and the subsequent election of a coalition government whose policy agenda for ‘tackling the deficit’. This chapter, as an update to the chapter by Tatli (2010), outlines the recent developments in equality and diversity at work in the UK. It begins with a brief summary of some key demographics and equality- related statistics. It then summarizes the key points made in the 2010 UK chapter. The chapter then moves on to identify the key changes in relation to the above mentioned responses to the global financial crisis. Since the publication of the 2010 chapter, the key shift in the equality and diversity landscape in the UK has been one of ideological and political rather than demographic, cultural or related to any notable shift in the dominant managerial discourse on the issue. As a result, equality and diversity has been radically reframed and resourced around the claims to an approach that pursues government austerity, but combined with a renewed focus on fairness, sometimes referred to in terms of a ‘big society’ agenda. This ideological shift – and its overspill into the framework of statutory rights on the issue – marks a significant change in UK approach to equality and diversity and, therefore, constitutes a key focus in this update chapter

    Agricultural Academy

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    Abstract DASKIRAN, I., S. CANKAYA, N. K. DARCAN and E. GUNES, 2010. A case study for production system analysis of Turkish Angora goat farms. Bulg. J. Agric. Sci.

    Moving societies and immobile organizational practices: The winding road of diversity management in Italy

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    In Italy, a concern with diversity management arose considerably later than in other western countries. This was due to various factors: Italy's particular productive system, which is largely made up of small and medium-sized enterprises, the belated onset of the internationalization and diversification of work, and probably cultural features specific to Italy (Bombelli, 2010; De Vita, 2010). It is mainly in the past decade that the concept of diversity management has spread beyond a narrow circle of experts and entered the broader academic debate and firms, where diversity-orientated personnel management initiatives have begun to gain ground, albeit sporadically and slowly, and to very different extents across the country (Barabino et al., 2001; Bombelli, 2003; Castellucci et al., 2009; Cocozza, 2010; Mauri and Visconti, 2004; Visconti, 2007). The main factors behind the diffusion of this approach have been: the growing presence of the multinationals and the spread of international cooperation agreements that imply intercultural management (Ambrosini, 2001; Decastri, 1993); the progressive feminization of the labour market and the growing female presence in traditionally masculine sectors (Bombelli, 2000; Gherardi and Poggio, 2007); the demands made by individuals of organizations regarding self-realization and a better balance between work and private life (Cuomo and Mapelli, 2007; Piazza et al., 1999); and the recommendations and financial support of the European Union (EU)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Understanding the Agency of Diversity Managers: A Relational and Multilevel Investigation.

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    PhDThis thesis aims to provide a critical realist account of diversity managers' agency, incorporating a critique of the existing diversity management research. A multilevel and relational analytical framework is offered in order to understand diversity managers' agency. The framework interpreted and operationalised Bourdieu's key concepts, `field', `habitus', `capitals' and `strategies' in the organisational context, for exploring and explaining macro, meso and micro level influences on the agency of diversity managers. The macro-social field of diversity management is mapped out by analysing data from an online national survey completed by diversity managers in the UK, and in-depth interviews with diversity managers of large public and private sector organisations. Then, findings of an extensive case study of Ford Motor Company, which includes company documentation and interviews with the company's diversity managers, are introduced to examine meso-organisational and micro-individual dynamics of diversity managers' agency. The analysis of the findings revealed that the agency of diversity managers is multilayered and complex. Whilst the boundaries of this agency are drawn by the deeply seated structures and mechanisms which are embedded in the fabric of social and organisational lives, diversity managers own varying degrees of social, cultural and symbolic capitals which are potential sources of power and influence, and they utilise strategies in order to activate this potential and widen the scope of their agency. The thesis addresses the limitations in diversity management literature, which are associated with dualisms of agency and structure, and qualitative and quantitative methods. It makes theoretical and methodological contribution by offering original empirical evidence generated through a multi-method strategy and analysing diversity managers' agency at the interplay of agentic and structural dynamics. It also offers policy makers at organisational and national levels a realistic understanding of diversity management processes that may inform design of more effective and progressive policies and initiatives.School of Business and Management Queen Mary University

    Protecting Animals 36: Author Witi Ihimaera

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    In this very special episode of Knowing Animals I am joined by beloved New Zealand author Witi Ihimaera. Witi has written many books featuring nonhuman animals. He offers us a non-colonial lens through which to think about the human/nonhuman relationship

    Author Under Sail The Imagination of Jack London, 1893-1902

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    In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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