22 research outputs found

    Inhaled aztreonam lysine vs. inhaled tobramycin in cystic fibrosis: a comparative efficacy trial.

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    Background: Open-label, parallel-group, international trial comparing aztreonam for inhalation solution (AZLI) and tobramycin nebulizer solution (TNS) for cystic fibrosis patients with airway Pseudomonas aeruginosa. Methods: 273 patients (≥ 6 years); randomized to three 28-day courses (AZLI 75 mg [three-times/day] or TNS 300 mg [twice/day]); 28 off-days separated each course. Results: 268 patients were treated (AZLI/TNS: 136/132). Mean baseline FEV1 was 52% predicted. Mean relative changes after 1 course (AZLI: 8.35%; TNS: 0.55%; p<0.001) and mean actual changes across 3 courses (AZLI: 2.05%; TNS: -0.66%; p=0.002) indicated AZLI statistical superiority vs. TNS. AZLI-treated patients had fewer respiratory hospitalizations (p=0.044) and respiratory events requiring additional antipseudomonal antibiotics (p=0.004); both treatments were well tolerated. 133 patients received 1 to 3 courses of AZLI treatment in the open-label extension-period (28-day courses separated by 28 days off-treatment); lung function improvements were comparable regardless of whether patients had received TNS or AZLI in the preceding comparative period. Conclusions: AZLI demonstrated statistical superiority in lung function and a reduction in acute pulmonary exacerbations compared to TNS over 3 treatment courses (ClinicalTrials.gov: NCT00757237)

    Preparing for life after university : the Youth Convention Programme 2023 / Nur Ilianis Adnan, Nur Husna Serip Mohamad & Noor Azli Affendy Lee

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    On January 7th, 2023, UiTMCPP's English Language club hosted a special virtual event named the Youth Convention Programme 2023. The event was live-streamed on the club's YouTube page and aimed to provide final year university students with valuable exposure from exceptional individuals in the industry. The former president of the club, Syed Amir Haikal bin Syed Hisham Alwi, and the newly elected club president, Nuralia Qistina binti Mohd Fadzlul Azim, acted as the hosts for the event. The event showcased three invited speakers: Arinah Najwa, Charissa Ong Ty, and Zack Shah. Each speaker presented their unique perspectives and experiences on the theme of life after university. Arinah Najwa, a senior analyst at BowerGroupAsia, discussed the importance of youth empowerment in the workforce towards nation-building. Charissa Ong Ty, the author of the bestselling book Midnight Monologues, as well as a poet and designer, shared her insights during a session titled "The Journey of Following Your Passion." Finally, Zack Shah, a UiTM alumnus and a copywriter at Nuren Group (Enlinea Sdn Bhd), talked about how UiTM instills valuable working skills in their graduates. The full-day event provided the audience with numerous ideas and insights to empower them in decision-making and to make better choices after graduation. The event was a culmination of past talk shows hosted by Syed Amir Haikal during his tenure in the club, namely Night Talks from April to July 2021, What's Up World from October 2021 to January 2022, and the International Youth Engagement Talk Series in May 2022. The hope is that events like these will not just expose students to the working world, but also encourage them to think about developing skills and knowledge through the opportunities provide

    BLOOD PRESSURE MONITORING SYSTEM

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    The project is named Blood Pressure (BP) Monitoring System. The expected results of this project are; to design and implement a reliable blood pressure measuring device and integrated with wireless technology for monitoring purpose. Author are required to build a device that measures blood pressure and transmit the readings wirelessly thus it can be displayed on the computer’s screen. In 26 weeks’ time, Author had successfully designed and implemented the circuitry of the system, and developed a coding to capture systolic and diastolic values. The project is fully completed and author managed to achieve all objectives where the BP measuring device is integrated with XBee Series 1 and able to transmit systolic and diastolic values to the computer wirelessly

    Gamma spectrometry for natural radioactive nuclides in Spa waters in some areas in north Algeria

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    The work aims to determine the radioactivity levels of Algeria thermal waters which have been used permanently in spas for therapeutic intentions. Eight Spas waters in north Algeria analysis was performed to determine their radioactivity concentration for 226Ra, 232Th, 235U and 40K, using a high-resolution HPGe γ-spectrometry system. Water is imbedded in a Marinelli beakers tightly sealed for 28 days to achieve secular equilibrium between 226Ra and its short-lived daughter products before analyzing by gamma ray spectrometry. The average activity concentrations for spa waters from study areas were 0.045 to 2.077 Bql-1 for 226Ra; 0.17to 3.416 Bql-1 for 232Th; 0.085to 7,235 Bql-1 for 235U and 1.402 to 15.156 Bql-1 for 40K. This study would be useful for used and official authorities for the assessment of radiation exposure risk due to usage of the considered spa waters. &nbsp
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