16,616 research outputs found

    The politics and economics of regulatory impact assessment

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    This is the author accepted manuscript. The final version is available from the publisher via the link in this record

    Phase Distribution Efficiency of cm-Scale Ultrasonically Powered Receivers

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    In the domain of ultrasonically powered biomedical implants, there is an increasing interest in cm-scale ultrasonic receivers (RX). However, when a single-element transducer is used as the RX transducer, an uneven phase distribution across the RX area can significantly reduce the harvestable power. In this paper, we investigate the impact of lateral and angular misalignment on the acoustic field phase distribution across the RX surface. We show that, for a single-element RX transducer, lateral misalignment has minimal effect on the harvestable power, whereas even small angular misalignments can cause a considerable reduction, especially for larger RX sizes. We present a potential solution that consists of subdividing a large RX transducer (e.g. 20 × 20mm2) into smaller elements, which significantly improves power transfer efficiency by taking advantage of the smaller phase variation across the surface of each element. The trade-offs between achieving a minimum acceptable power transfer efficiency and managing the increased complexity in packaging and matching circuitry are also discussed.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Components, Technology and MaterialsBio-Electronic

    Highly efficient laser-driven Compton gamma-ray source

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    The recent advancement of high-intensity lasers has made all-optical Compton scattering become a promising way to produce ultrashort brilliant gamma-rays in an ultra-compact system. However, so far achieved Compton gamma-ray sources are limited by low conversion efficiency and spectral intensity. Here we present a highly efficient gamma photon emitter obtained by irradiating a high-intensity laser pulse on a miniature plasma device consisting of a plasma lens and a plasma mirror. This concept exploits strong spatiotemporal laser-shaping process and high-charge electron acceleration process in the plasma lens, as well as an efficient nonlinear Compton scattering process enabled by the plasma mirror. Our full three-dimensional particle-in-cell simulations demonstrate that in this novel scheme, brilliant gamma-rays with very high conversion efficiency (higher than 10(-2)) and spectral intensity (similar to 10(9) photons/0.1%BW) can be achieved by employing currently available petawatt-class lasers with intensity of 10(21) W cm(-2). Such efficient and intense gamma-ray sources would find applications in wide-ranging areas. ©2019 The Author(s)

    CM Periods, CM Regulators, and Hypergeometric Functions, I

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    We prove the Gross-Deligne conjecture on CM periods for motives associated with H-2 of certain surfaces fibered over the projective line. Then we prove for the same motives a formula which expresses the K-1-regulators in terms of hypergeometric functions F-3(2), and obtain a new example of non-trivial regulators

    Mapping SNOMED CT to ICD-10-CM

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    A SNOMED CT-encoded problem list is required to satisfy the Certification Criteria for Stage 2 “Meaningful Use”. ICD-10-CM has replaced ICD-9-CM as the reimbursement code set in 2015. Having a cross-map from SNOMED CT to ICD-10-CM would promote the use of SNOMED CT as the primary problem list terminology, while easing the transition to ICD-10-CM. There is no established principle and methodology on systematically and semantically linking SNOMED CT to ICD-10-CM. This research project describes the development of mapping principle, mapping guidelines, mapping tools and mapping methodology for a rule-based crosswalk to support semi-automatic generation of ICD-10-CM codes from SNOMED CT-encoded data. A series of mapping guidelines were developed based on the clinical use case, SNOMED CT modeling convention, and ICD-10-CM classification guidelines. One of the important methodology in developing the map set is using triangulation in generating legacy maps. Using the SNOMED CT to ICD-9-CM map and General Equivalence Mappings sequentially, Indirect Map was generated from SNOMED CT to ICD-10-CM for 96.2% of the SNOMED CT concepts within the scope of the study. Another innovation in this crossmapping research is implementation of a principle to handle age specification. The age rule was one type of rule to handle cases in which one SNOMED CT concept can map to different ICD-10-CM codes depending on the age of the patient. The age rule quality assurance (QA) was a mechanism to capture the age specification that can be easily missed by manual mapping. The results showed that the mapping guidelines ensured the mapping consistency, which potentially would reduce the mapping discrepancy between the two independent parallel mapping efforts. It also made it possible that the map set can be used in a meaningful way when data is exchanged. On this triangulation method in generating legacy map, an Indirect Map generated from SNOMED CT to ICD-10-CM covered a very high percentage of SNOMED CT concepts. Overall, this Indirect Map had a moderate degree of agreement with the Direct SNOMED CT to ICD-10-CM map. However, the indirect synonymy maps have much higher precision and can be used for quality assurance (QA) of the three maps. The age rule QA identified 342 out of 7,277 concepts which potentially required age rules, among these 50.3% turned out to be true positives. Without this QA, a large proportion of age rules in the published Map would have been missed. The outcomes of this research project include a set of mapping principle, mapping guidelines, mapping tools and mapping methodology for a rule-based crosswalk from SNOMED CT to ICD-10-CM. All these could be used as a prototype in other cross standard mappings. For example, in the US, ICD-10-PCS officially replaced ICD-9-CM from October 2015 onwards. A project was formulating earlier this year (2015) for the purpose of creating the map from SNOMED CT procedure to ICD-10-PCS. It is a pleasant finding that tooling, principles and guidelines established in SNOMED CT to ICD-10-CM mapping can be re-used, with modifications, for the PCS mapping process.Ph.D.Includes bibliographical referencesby Junchuan X

    Food habits of young-of-year striped bass in association with other gamefish in Norris Reservoir, Tennessee

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    Of the 135,401 striped bass young-of-year (y-o-y) fingerlings stocked at four study sites in Norris Reservoir in 1995, only 106 were recaptured using electrofishing, gill nets and seines. Food habit analysis was performed on all striped bass; a representative sample of largemouth (n=93) and smallmouth (n=22) bass y-o-y were also examined for food items ingested. Midge and mayfly larvae, copepods, and Daphnia lumholtzi were the dominant food items found in fish less than 7 cm in length. On reaching 7 cm in length, y-o-y striped bass preyed primarily on larval shad (Dorosoma spp.). Striped bass attained this length approximately two weeks earlier in the growing season than largemouth; smallmouth switched to fish approximately four weeks after the largemouth. Largemouth preyed on shad, bluegill, and other largemouth while smallmouth utilized bluegill almost exclusively

    Dihedral Artin representations and CM fields

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    For a fixed CM field K with maximal totally real subfield F, we consider dihedral Artin representations of F induced from K. We prove that a positive proportion of such representations have image D4.First author draf

    Author reply

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    Health data linkage in Australia remains challenging1 as reflected in our recent experience of multi‐jurisdictional data linkage. We welcome the Population Health Research Network (PHRN) collaborative's initiatives in establishing a streamlined and unified application process in multi‐jurisdictional data linkage projects, and we fully support their vision. We acknowledge the concerns raised by Flack and Smith2 and take this opportunity to elaborate.Full Tex

    Data Cleaning for Deterministic Data Linkage for Sports and Recreational Injuries Using ICD-9 and ICD-9-CM

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    We have included SAS syntax examples for cleaning emergency department and inpatient hospital data from 2006 to 2012 (in ICD-9-CM) format from the Florida Agency for Healthcare Administration. The provided syntax (in .sas format and .py format), demonstrates how we took original data sets, restricted it to specific variables, reformatted it for our purposes, and transposed it to create two separate data sets that were then merged together to create an all-encompassing data set for individual level analysis. Syntax covered under GPL-3.0-or-later. In addition, we have provided figures (author Baker) demonstrating the linkage process. One figure (Titled Figure 7) shows the steps to put together data from several years and retain all variables. The second figure (Titled Figure 8) shows the steps to take the final data sets created in Figure 7 and then create one master data set using merging. The figures are covered under a CC-BY-SA-4.0 license. </p
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