15 research outputs found
Taking Flight in Condemned Grounds: Forcibly Displaced Karens and the Thai-Burmese In-Between Spaces
Based on fieldwork in non-ceasefire war zones within and between Thailand and Burma, this article explores the nexus between written language, intelligibility, and qualified voice in order to examine the Karen people as unqualified political subjects in a quotidian theater of the displaced. </jats:p
Imperceptible naked-lives and atrocities: forcibly displaced peoples and the Thai-Burmese in-between spaces
This study follows the becomingness of the Karens: as an indigenous people, as an ethnic nationality, as an ethnic minority, and as a forcibly displaced people. The questions that guide this dissertation are: What is it like to be forcibly displaced beings, taking flight in, following Walter Benjamin, the real state of exception? How can the Karens transgress those grave conditions, and at what costs? Why has protecting them from the wrongs done to them been, by and large, impossible? Why have their struggles and sufferings not been adequately perceived? As political theory, the dissertation interweaves notions of violence, perceptibility, and protection. The study is also informed by the symbolic and experiential conditions of forcibly displaced Karens along the Thai-Burmese border zones. This study evinces four major issues: firstly, how Karens' forms-of-life have been stripped off and their nakedness revealed by the Burmese and Thai nation-states; secondly, how their struggles and sufferings have been imperceptible because the Karens have been rendered as unqualified political subjects and because we - the peoples who have adequate juridical protections - view the world only from state-centric paradigms, and only hear a single voice, i.e., the univocity of statist discourses; thirdly, how the paradox of perceptibility, where the very power that has attempted to render the Karens' sufferings imperceptible is, willingly or not, the same power that enables them to strengthen their form-of-life as a Karen nation; and, finally, how the forcibly displaced Karens' quotidian lives have not confirmed the glories of the Appadurian ethnoscape. They are not parts of the subjectivities who can freely move in this world. On the contrary, they have often been recognized as the parts that have no parts in the human community. They are "the exception" in motion whose lives have been under fire, dreaming passionately of becoming parts of the "general." They have dreamt to live such lives for more than half a century, ever since they officially started their "revolution" in 1948. One of the most important arguments, therefore, is that, as forcibly displaced peoples, the Karens are political subjects and not sheer facts of living.Ph.D
Sick Kingdom: The Role and Politics of Thai Health Care in the Domination of Bhumibol's Narrative
病める王国―タイ王党派の物語りの政治―
京都大学新制・課程博士博士(地域研究)甲第24016号地博第295号新制||地||114(附属図書館)京都大学大学院アジア・アフリカ地域研究研究科東南アジア地域研究専攻(主査)教授 玉田 芳史, 教授 片岡 樹, 准教授 TANGSEEFA Decha学位規則第4条第1項該当Doctor of Area StudiesKyoto UniversityDFA
Newsletter : Center for Southeast Asian Studies, Kyoto University No.72
Editorial [3]Thailand's Royalist Democracy in Crisis … Thongchai Winichakul [4]Royal Succession at Stake: The Future of the Thai Monarchy … Pavin Chachavalpongpun [7]Thailand Purports to Be in Search of an Upright Political System, But Can "Democracy" Still Be Regarded as a Viable Option? … Titipol Phakdeewanich [10]Thailand: A Year After … Tanet Charoenmuang [13]"Constituting" the Nation: Modern-day Thai-style Dictatorship … David Streckfuss [16]Understanding Climate Change Impacts and Adaptation Mechanism in Cambodia … Sothun Nop [18]Researching the Indonesia's 1965 Tragedy Today: A View from within … Agus Suwignyo [23]Youth, Voice, and Methodology: Learning (with) Young Migrants in a "Temporary Shelter Area" … Decha Tangseefa [27]Library [31]Publications [33]Fellows [34
Preconditioning serum levels of inflammatory proteins as a tool to estimate the risk of graft versus host disease in hematopoietic stem cell transplantation
Orientador: Erich Vinicius de PaulaDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências MédicasResumo: O transplante de células tronco hematopoiéticas (TCTH) contempla uma mortalidade relacionada ao transplante substancial e traz a doença do enxerto-contra-hospedeiro aguda (DECHa) como uma das autoras deste desfecho, justificando, assim, esforços contínuos para melhor estratificar os pacientes quanto aos seus riscos. Neste cenário, a descoberta e validação de novo biomarcadores da DECHa, que é hoje uma das áreas mais dinâmicas da pesquisa em TCTH, tem permitido a identificação de diversas proteínas potencialmente informativas no contexto da DECHa. No entanto, a utilidade destes biomarcadores na estratificação de risco pré-TCTH é limitada, especialmente pelo fato de que a ampla maioria deles é detectada durante as fases mais tardias (pós-condicionamento) do TCTH. É neste contexto que a associação entre o status clínico do receptor antes da realização do TCTH, e a ocorrência de DECHa, vem sendo explorada na literatura nos últimos anos. Índices que quantificam a carga (burden) de comorbidades, utilizados em diversas áreas da medicina para estratificação de risco, foram adaptados especificamente para receptores de TCTH, através do índice HCT-CI, que se revelou capaz de estimar o risco de mortalidade relacionada ao transplante e, mais recentemente, de DECHa. Um aspecto relevante do HCT-CI é que a introdução de dados laboratoriais indiretamente relacionados à presença de comorbidades aumentou substancialmente sua acurácia. Nos últimos anos, a análise específica ou conjunta de proteínas inflamatórias no soro tem sido usada na prática clínica como importante indicador da presença e extensão da inflamação na avaliação de diversas doenças e comorbidades. Assim, no presente estudo, nós avaliamos a hipótese que os níveis basais de alguns marcadores inflamatórios de uso rotineiro, ao refletirem a presença de comorbidades, poderiam contribuir para a estratificação de risco em pacientes submetidos a TCTH alogênico. Deste modo, o objetivo do nosso estudo foi avaliar a associação entre o desenvolvimento de DECHa e níveis basais de proteínas inflamatórias comumente utilizadas na prática clínica. Antes do condicionamento, os níveis de lactato desidrogenase, albumina, ferritina, ferro sérico, capacidade total de ligação de ferro e ?eta 2-microblobulina foram dosados em uma coorte prospectiva de 103 pacientes, dos quais 26 desenvolveram DECHa; considerando mortalidade precoce e recaída como evento competitivo. Entre as proteínas inflamatórias avaliadas, a ?2-microglobulina permaneceu significativa em vários modelos estatísticos como relacionada à ocorrência de DECHa, mesmo quando neutralizado o possível efeito da idade (HR 3,72 - IC95%: 1,12-12,34 - p = 0,03) e presença de doenças linfoproliferativas (HR 4,44 - IC95%: 1.12-17.5 - p = 0,03). Em conclusão, a associação entre ?2-microglobulina e a ocorrência de DECHa sugere que a dosagem desta proteína antes do TCTH possa representar um elemento a mais para a estratificação de risco de DECHaAbstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) entails substantial nonrelapse mortality (NRM) and brings acute graft-versus-host disease (GVHD) as the main author of this outcome, which justifies continued efforts to better risk stratify patients. In this scenario, discovery and validation of new biomarkers of GVHD, which is today one of the most dynamic areas of research in HSCT, has allowed the identification of several proteins potentially informative in the context of GVHD. However, the utility of these biomarkers in HSCT risk stratification is limited, especially by the fact that the vast majority of them is detected in pos-HSCT period (post-conditioning). In this context, recently, the association between the clinical status of the recipient prior to the HSCT and the occurrence of GVHD has been explored. Several indices that measure the burden of comorbidities, used in many areas of medicine for risk stratification, have been adapted specifically for HSCT recipients through the HCT-CI index, which proved able to estimate the risk of transplant-related mortality and, more recently, aGVHD. An important aspect of the HCT-CI is that the introduction of laboratory data constituted the main change for increasing its accuracy. In the last years, the specific or combined inflammatory analysis of serum proteins has been used in clinical practice as an important indicator of the presence and extent of inflammation in the evaluation of various diseases and comorbidities. In the present study, we evaluated the hypothesis that baseline levels of some routine inflammatory markers, reflecting the presence of comorbidities, could contribute to risk stratification in patients submitted to allogeneic HSCT. Thus, the aim of our study was to evaluate the association between the development of aGVHD and baseline levels of inflammatory proteins commonly used in clinical practice. Before conditioning, the levels of lactate dehydrogenase, albumin, ferritin, serum iron, total iron-binding capacity and ?eta 2-microblobulin were measured in a prospective cohort of 103 patients, of which 26 developed GVHD; considering early relapse and mortality as a competitive event. Among the assessed inflammatory markers, ?2-microglobulin remained significant in several statistical models as related to the occurrence of GVHD, even when neutralized the possible effect of age (HR 3,72 - CI95%: 1,12-12,34 - p = 0,03) and the presence of lymphoproliferative disorders (HR 4,44 - CI95%: 1.12-17.5 ¿ p= 0.03). In conclusion, the association between ?2-microglobulin and the occurrence of GVHD suggests that the dosage of this protein before HSCT might represent an additional element for risk stratification of aGVHDMestradoClinica MedicaMestra em Ciências2013/09319-0FAPE
Soldiers, monks, borders: Violence and contestation in the greater Mekong Sub-region
The struggles of poor communities to negotiate development processes have been documented increasingly in recent years. However, recognition of the agency of the poor should not preclude attention to patterns of oppression that may be intensifying in the face of top-down development processes imposed by increasingly well co-ordinated elites. Examination of patterns of violence in border areas across the Greater Mekong Sub-region suggests that integration facilitates the collusion of state actors in the dispossession of the poor in a manner that is deleterious to ethnic minorities, internal migrants and other vulnerable populations. National political processes are not offering mechanisms by which such populations can seek to contest this trend
Community engagement for malaria elimination in contested areas of the Karen/Kayin State, Myanmar: A case study on the Malaria Elimination Task Force
Background: This study evinces how the community engagement (CE) approach of the Malaria Elimination Task Force (METF) in the Karen/Kayin State of southeast Myanmar contributed to generating participation in program activities, such as early detection and treatment, malaria blood surveys and mass drug administration. Methods: We investigated the CE approach through ethnographic and key-informant unstructured interviews as well as focus group discussions and participant observation with program participants METF team members. Interview transcripts were analysed manually applying inductive content analysis. Results: In the context of the Thai-Myanmar border, CE had two main dimensions: The first was to enable the politically sensitive entry of the program into intervention areas, the second was to create mutual understanding among the METF team and people from the population and gain trust. For the first, the METF needed to acknowledge, get permission and communicate with a complex landscape of governing actors and leaders. For the second, creating mutual understanding meant to spend time learning about villagers’ lifeworlds and adapting engagement accordingly to create understanding of the program in resonance with these lifeworlds. Gaining trust meant to leverage leadership and build trust through informal “horizontal” engagement and acts of caring. Three key dimensions of villagers’ lifeworlds that appeared most crucial for staff to learn about were: villagers’ experience with the outside world; leadership and governing relationships to villagers: authority and distrust; and their perceived need for malaria care. Conclusions: Successful CE is highly context specific. CE success was based on the adaptability of the approach towards the complex political and socio-cultural contexts of the different areas of the Karen/Kayin State. Hence, CE is not a fixed approach or strategy defined before entering the setting, but constantly evolving based on the encounters with stakeholders and people of the population.</ns4:p
