15,766 research outputs found
Effects of ambient temperature on volume, specialty composition and triage levels of emergency department visits.
No full textThe construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Improving interoperability in distributed and physical union catalogues through co-ordination of cataloguing and indexing policies : report for work package B of the JISC CC-interop project
Full text linkThis report addresses section 7.2.4 (Guidelines and Strategy for Cataloguing and Indexing Standards) of the CC-interop project plan and fulfills deliverable B3 of work
package B
jDHBenelux Author Template
No full textThis repository contains the latest official GitHub hosted versions of the LaTeX template that authors are required to use when they finalize their contribtions to the DH Benelux Journal. The repository synchronises with the corresponding easy-to-use and well-documented Overleaf Template that provides authors with a low threshold environment for writing LaTeX – but can be used with any LaTeX compiler.
About this Release: Apart from some minor changes to the .cls, v2.0 introduces a number of new files to improve open source development with git and GitHub, including a README, a CC-BY 4.0 License, and a .gitignore file. It also prepares the repository for synchronisation with Zenodo, to improve sustainability.
Full Changelog: https://github.com/DHBenelux/jDHBenelux-author-template/compare/v1.1...v2.
Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan
No full textPurpose\uef\ubc
Many single nucleotide polymorphisms (SNPs) have been found to be associated with breast cancer but their SNP interactions are seldom addressed. In this study, we focused on the joint effect for SNP combinations of seven CXCL12-related genes involved in major cancer related pathways.
Patients and Methods\uef\ubc
SNP genotyping was determined by PCR-restriction fragment length polymorphism (RFLP) in this study (case = 220, control = 334). Different numbers of combinational SNPs with genotypes called the pseudo-haplotypes from different chromosomes were used to evaluate their joint effect on breast cancer risk.
Results\uef\ubc
Except for VEGF rs3025039-CT, none of these SNPs was found to individually contribute to breast cancer risk. However, for two combined SNPs, the proportion of subjects with breast cancer was significantly low in the pseudo-haplotype with CC-GG genotypes in rs2228014-1801157 (CXCR4-CXCL12) compared to those with non-CC-GG genotypes. Similarly, the pseudo-haplotype of rs12812942-rs2228014-rs3025039 (CD4-CXCR4-CXCL12) And rs12812942-rs3136685-rs2228014
-rs1801157(CD4-CCR7-CXCR4-CXCL12)with specific genotype pattern (AT-CC-CC and AT-AG-CC-GG) among three and four combinational SNPs were significantly low in breast cancer occurrence. More SNP combinations larger than five SNPs were also addressed and shown the
similar effect.
After controlling for age, comparing to their corresponding non-pseudo-haplotypes, the estimated odds ratios for breast cancer ranged between 0.20 and 0.71 for specific pseudo-haplotypes with two to seven SNPs.
Conclusion\uef\ubc
We have identified the potential combined CXCL12-related SNPs with genotypes that were protective against breast cancer and may have an impact on identification of a low risk population for the development of breast cancer
Glycemic control is related to the severity of impaired thermal sensations in type 2 diabetes.
No full textScalar soliton quantization with generic moduli
Full text linkThis article is distributed under the terms of the Creative Commons
Attribution License (CC-BY 4.0), which permits any use, distribution and reproduction in
any medium, provided the original author(s) and source are credArticle funded by SCOAP3. CP is
a Royal Society Research Fellow and partly supported by the U.S. Department of Energy
under grants DOE-SC0010008, DOE-ARRA-SC0003883 and DOE-DE-SC0007897. ABR
is supported by the Mitchell Family Foundation. We would like to thank the Mitchell
Institute at Texas A&M and the NHETC at Rutgers University respectively for hospitality
during the course of this work. We would also like to acknowledge the Aspen Center
for Physics and NSF grant 1066293 for a stimulating research environment which led to
questions addressed in this paper
Additional file 2 of The effect and mechanism of Jiao-tai-wan in the treatment of diabetes mellitus with depression based on network pharmacology and experimental analysis
No full textAdditional file 2: Figure S1. The top 20 BP, MF and CC in GO analysis of 117 intersection targets
Serum Amyloid A Induces Lipolysis by Downregulating Perilipin Through ERK1/2 and PKA Signaling Pathways.
No full text- …
