8,995 research outputs found
The North Sea Andrea storm and numerical simulations
No full text© Author(s) 2014. A coupling of a spectral wave model with a nonlinear phase-resolving model is used to reconstruct the evolution of wave statistics during a storm crossing the North Sea on 8-9 November 2007. During this storm a rogue wave (named the Andrea wave) was recorded at the Ekofisk field. The wave has characteristics comparable to the well-known New Year wave measured by Statoil at the Draupner platform 1 January 1995. Hindcast data of the storm at the nearest grid point to the Ekofisk field are here applied as input to calculate the evolution of random realizations of the sea surface and its statistical properties. Numerical simulations are carried out using the Euler equations with a higher-order spectral method (HOSM). Results are compared with some characteristics of the Andrea wave record measured by the down-looking lasers at Ekofisk.sponsorship: This work has been supported by EU project EXTREME SEAS (SCP8-GA-2009-234175). The F.W.O. project G.0333.09 is also acknowledged. L. Fernandez and J. Monbaliu also acknowledge the Hercules Foundation and the Flemish Government department EWI for providing access to the Flemish Supercomputer Center. E. M. Bitner-Gregersen and A. Toffoli thank Miguel Onorato and Carlo Brandini for fruitful discussions. (EU project EXTREME SEAS|SCP8-GA-2009-234175, F.W.O. project|G.0333.09)status: Publishe
Antenati ed eredi di Burghiba. Continuità e cesure nella costruzione dello Stato-nazione in Tunisia
No full textThe paper inquiries how the concept of State has been translated into a political-institutional and discursive order throughout modern Tunisian history. It focuses on three key moments: the modernization in the XIX century, the independence in the Fifties and the revolt of 2010-2011. This overview allows to highlight the continuities and the ruptures characterizing the path of the Tunisian State, locating in Bourguiba’s era the central moment in which the characters of the Tunisian State, only partially challenged by the revolt of 2010-2011, were fixed
Aptamer-enriched scaffolds for tissue regeneration: a systematic review of the literature
No full textIntroduction: Aptamers are a brand-new class of receptors that can be exploited to improve the bioactivity of tissue engineering grafts. The aim of this work was to revise the current literature on in vitro and in vivo studies in order to i) identify current strategies adopted to improve scaffold bioactivity by aptamers; ii) assess effects of aptamer functionalization on cell behavior and iii) on tissue regeneration. Methods: Using a systematic search approach original research articles published up to 30 April 2022, were considered and screened. Results: In total, 131 records were identified and 18 were included in the final analysis. Included studies showed that aptamers can improve the bioactivity of biomaterials by specific adsorption of adhesive molecules or growth factors from the surrounding environment, or by capturing specific cell types. All the studies showed that aptamers ameliorate scaffold colonization by cells without modifying the physicochemical characteristics of the bare scaffold. Additionally, aptamers seem to promote the early stages of tissue healing and to promote anatomical and functional regeneration. Discussion: Although a metanalysis could not be performed due to the limited number of studies, we believe these findings provide solid evidence supporting the use of aptamers as a suitable modification to improve the bioactivity of tissue engineering constructs
Reagire alla post-verità. Un bilancio e un monito
No full textL’occasione di apportare un contributo alla presente discussione sul ruolo del sapere nella società contemporanea appare oggi agli occhi di chi scrive doppiamente proficua. Da un lato, essa sollecita l’esigenza di guardare con occhio critico alle ricadute sociali e politiche del lavoro intellettuale, mentre dall’altro (complice una fortunata coincidenza temporale) invita a concentrarsi su una materia particolarmente atta a questo scopo. L’8 novembre 2022 correva infatti il sesto anniversario di uno degli eventi che più hanno infiammato l’immaginario delle liberaldemocrazie occidentali contemporanee: l’elezione del termine “post-verità” a parola dell’anno 2016 [...
Andrea Bacová
No full textAndrea Bacová focuses on research and teaching in the field of residential architecture. Her work includes systematic research on residential buildings and their urban context. She actively participates in promoting Slovak architecture and is the author of several publications and exhibitions
Viewer-, Author-, and Ownership in the Work of Andrea Zittel
No full textAndrea Zittel invites others to collapse the distinctions between artist, viewer, and collaborator by interacting with her usable works. This thesis explores the process of interacting with Zittel\u27s works, and how it affects viewer-, author- and ownership
Preparation of hybrid samples for scanning electron microscopy (SEM) coupled to focused ion beam (FIB) analysis: A new way to study cell adhesion to titanium implant surfaces
No full textThe study of the intimate connection occurring at the interface between cells and titanium implant surfaces is a major challenge for dental materials scientists. Indeed, several imaging techniques have been developed and optimized in the last decades, but an optimal method has not been described yet. The combination of the scanning electron microscopy (SEM) with a focused ion beam (FIB), represents a pioneering and interesting tool to allow the investigation of the relationship occurring at the interface between cells and biomaterials, including titanium. However, major caveats concerning the nature of the biological structures, which are not conductive materials, and the physico-chemical properties of titanium (i.e. color, surface topography), require a fine and accurate preparation of the sample before its imaging. Hence, the aim of the present work is to provide a suitable protocol for cell-titanium sample preparation before imaging by SEM-FIB. The concepts presented in this paper are also transferrable to other fields of biomaterials research
Retracted articles in endodontic-related literature: an analysis of 60 cases
No full textA B S T R A C T INTRODUCTION: The number of retracted articles in the bio-medical field, including dentistry, is increasing. The objective of this study was to identify retracted articles in endodontic-related literature and outline their main characteristics. EVIDENCE ACQUISITION: The Medline and Scopus databases were searched in January 2024. Additional records were identified by consulting the online database www.retractiondatabase.org. Retracted articles concerning endodontic topics and the relative retraction notes were retrieved and relevant data extracted. EVIDENCE SYNTHESIS: Sixty articles were identified, published between 2004 and 2022, with a mean of 3.0±2.3 retracted articles per year. The number of retracted articles per year did not significantly grow over time. The average time between the article and retraction note publication was 36.1±22.3 months. The majority of articles originated from Asia and were in-vitro studies. Only 6.7% of the articles were retracted due to honest errors. The main reasons of retraction were image/data manipulation (20%), plagiarism (18%), unavailability of raw data (10%), authorship issues (10%) and publication process issues (10%). A single research group accounted for 17 retractions. CONCLUSIONS: Unlike the dental field, the number of retracted articles in endodontics has not increased significantly over the time period considered. Despite this, controls against research misconduct must be increased to preserve the credibility of scientific research
The Lettere of Andrea Calmo: authorial artifices and historical reality
No full textopenNonostante l’edizione di Vittorio Rossi del 1888, la raccolta di "ingegnosi cheribizzi" e di "fantastiche fantasie" di Andrea Calmo è ancora avvolta da un certo mistero. L’autore, dissimulando la propria identità dietro alla “maschera” dell’umile pescatore veneziano, è stato in grado di offrire uno spaccato della cultura e della società nella Venezia cinquecentesca.
In particolare, è il quarto libro delle Lettere ad aver suscitato maggiore interesse tra gli studiosi ed i lettori: pubblicato nel 1566, a diversi anni di distanza dai primi tre, questo libro si distingue per il fatto che tutte le epistole sono indirizzate a delle donne immaginarie o realmente esistite.
In questa sede si propone, in primo luogo, uno studio della biografia del Calmo accompagnata da un’analisi del contesto storico-culturale della Venezia cinquecentesca; in secondo luogo, invece, viene proposto un commento di alcune lettere dell’ultimo libro dell’opera calmiana, che cerchi di far luce principalmente sull’aspetto linguistico e contenutistico del testo.Despite Vittorio Rossi's 1888 edition, Andrea Calmo's collection of "ingegnosi cheribizzi" and "fantastiche fantasie" is still shrouded in a certain mystery. The author, dissimulating his own identity behind the "mask" of the humble Venetian fisherman, was able to offer a cross-section of culture and society in sixteenth-century Venice.
In particular, it is the fourth book of the Letters that has aroused greater interest among scholars and readers: published in 1566, several years after the first three, this book stands out for the fact that all the epistles are addressed to women imaginary or actually existed.
Here we propose, first of all, a study of Calmo's biography accompanied by an analysis of the historical-cultural context of sixteenth-century Venice; secondly, however, a commentary on some letters from the last book of Calmo's work is proposed, which seeks to shed light mainly on the linguistic and content aspect of the text
Testosterone Enanthate: An In Vitro Study of the Effects Triggered in MG-63 Cells
No full textThe aim of this study was to investigate the effects of the androgenic hormone testosterone enanthate (TE) on human MG-63 cells. MG-63 were cultured for 24 h in the presence of TE at increasing concentrations to assess its lethal dose. Therefore, the suitable concentration for a prolonged use of TE in vitro was assessed by viability assay over 9 days. Finally, MG-63 were exposed to TE for 14 days and assayed for differentiation by qPCR and Alizarin Red S staining. TE in the amount of 100 µM resulted as the maximum dose tolerated by MG-63 cells after 24 h. However, a prolonged exposure in culture TE in the amount of 100 µM showed a cytostatic effect on cell proliferation. On the contrary, TE 10 µM was tolerated by the cells and did not boost cell proliferation, but did enhance new bone formation, as revealed by COL1A1, ALPL, BGLAP, and IBSP gene expression after 3, 7, and 14 days, and calcium deposition by Alizarin Red S staining after 14 days. Based on the current study, 10 µM is the critical dose of TE that should be used in vitro to support bone differentiation of MG-63 cells
- …
