1,720,967 research outputs found
Effetto Della Restrizione Calorica Sulle Modificazioni Epatiche Legate Ai Processi Di Invecchiamento Nel Modello Animale Killifish Turchese (Nothobranchius Furzeri, Jubb 1971).
No full textADVANCED GLYCATION END PRODUCTS AND THEIR INVOLVEMENT IN TURQUOISE KILLIFISH (NOTHOBRANCHIUS FURZERI, JUBB 1971) LIVER PATHOLOGIES.
No full text
AGE-RAGE system and apoptosis-related markers expression in age-related liver pathologies and spontaneous tumorigenesis in the shortest-lived vertebrate Turquoise Killifish (Nothobranchius furzeri, Jubb 1971).
No full textResveratrol prevents age-dependent motor and cognitive decline and prolongs life span in a short-lived vertebrate
No full textAge-dependent remodelling of retinal circuitry
No full textWe have investigated morphological changes in second-order neurons of the mouse retina during aging by using immunohistochemistry and electron microscopy. We observed sprouting of rod bipolar cells dendrites and horizontal cells arborizations: neuronal processes of both neuronal types showed irregular extensions beyond the outer plexiform layer, toward the outer limiting membrane, as well as into the outer nuclear layer (ONL). These processes were first observed in animals of 12 months of age and increased in numbers steadily until 24 months, which represent the last age examined. The ectopic processes are decorated by puncta immunoreactive for pre-synaptic markers typical of photoreceptor terminals juxtaposed to post-synaptic neurotransmitter receptors, demonstrating the presence of the entire molecular machinery of functional synapses. Electron microscopy confirmed that ectopic processes receive synapses from photoreceptor terminals. We conclude that during the second year of Life retinal rod bipolar and horizontal cells undergo sprouting and form ectopic synapses in the ONL. (C) 2007 Elsevier Inc. All rights reserved
Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
- …
