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    Pigs contra circovirus. Protection of pigs vaccinated with inactivated subunit vaccine [Sertések kontra circovírus inaktivált alegységvakcinával immunizált sertések védettsége]

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    The authors carried out vaccination on a pig farm fattening for high weight, where they demonstrated earlier the presence of and loss due to porcine circovirus (PCV2). From the two groups (261-261 animals) kept under the same conditions, one was vaccinated with sub-unit vaccine at weaning, at the age of 27 days, while the other was not vaccinated. At the time of vaccination all pigs of both groups were negative by PCR test. In the control group 4 weeks after weaning and also before slaughtering PCVD occurred in clinical signs, and PCR-test proved viraemia. Death rate and culling was higher in all stage of rearing in the control group: all death was 12.6 v. 4.2%, and culling 13.8 v. 7.3%. Carcase weight of pigs slaughter on 303rd day was larger by 5.1 kg in the vaccinated group. Single vaccination with inactivated sub-unit vaccine at the weaning gave adequate protection for 9 months against circovirus infection

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    ANTIBODY RESPONSE TO MYCOPLASMA HYOPNEUMONIAE INFECTION IN VACCINATED PIGS WITH AND WITHOUT MATERNAL ANTIBODIES INDUCED BY SOW VACCINATION

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    Abstract: Vaccination with bacterins is an important tool for the control of Mycoplasma hyopneumoniae infection of pigs. Because such vaccination often involves piglets that have suckled M. hyopneumoniae antibody-positive dams it is important to understand the effect of pre-existing (passively acquired) antibody on vaccine-induced immunity. To investigate this issue experimentally, 20 sows that were seronegative for M. hyopneumoniae were selected from a M. hyopneumoniae-infected herd and then randomly allocated to one of four treatment groups (five sows/group): Group A, vaccinated sows/vaccinated piglets; Group B, vaccinated sows/non-vaccinated piglets; Group C, non-vaccinated sows/vaccinated piglets; Group D, non-vaccinated sows/non-vaccinated piglets. Sows (Groups A and B) were vaccinated 14 days before farrowing and seroconverted within the next 14 days. Conversely, none of the non-vaccinated sows was seropositive at farrowing. Piglets (Groups A and C) were vaccinated when they were 7 days of age. Regardless of treatments none of the piglets had any evidence of an active immune response until many of those of Groups A and C and a few of those of Groups B and D seroconverted after it had been shown that at least some pigs of all groups had been naturally infected with a field strain of M. hyopneumoniae. This pattern of immune responsiveness (i.e. the collective results of Groups A, B, C and D) suggested that vaccination of pigs had primed their immune system for subsequent exposure to M. hyopneumoniae, and that passively acquired antibody had little or no effect on either a vaccine-induced priming or a subsequent anamnestic response. According to the statistical analysis sow serological status did not interfere with the antibody response in early vaccinated piglets. In conclusion, the results pointed out that early vaccination of piglets may assist M. hyopneumoniae control independently from the serological status of sows
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