4,293 research outputs found
13. Tada-no-in
No full textIwao Seiichi, Iyanaga Teizō, Ishii Susumu, Yoshida Shōichirō, Fujimura Jun'ichirō, Fujimura Michio, Yoshikawa Itsuji, Akiyama Terukazu, Iyanaga Shōkichi, Matsubara Hideichi. 13. Tada-no-in. In: Dictionnaire historique du Japon, volume 19, 1993. Lettre T. p. 4
{TADA}: {T}axonomy Adaptive Domain Adaptation
No full textTraditional domain adaptation addresses the task of adapting a model to a novel target domain under limited or no additional supervision. While tackling the input domain gap, the standard domain adaptation settings assume no domain change in the output space. In semantic prediction tasks, different datasets are often labeled according to different semantic taxonomies. In many real-world settings, the target domain task requires a different taxonomy than the one imposed by the source domain. We therefore introduce the more general taxonomy adaptive domain adaptation (TADA) problem, allowing for inconsistent taxonomies between the two domains. We further propose an approach that jointly addresses the image-level and label-level domain adaptation. On the label-level, we employ a bilateral mixed sampling strategy to augment the target domain, and a relabelling method to unify and align the label spaces. We address the image-level domain gap by proposing an uncertainty-rectified contrastive learning method, leading to more domain-invariant and class discriminative features. We extensively evaluate the effectiveness of our framework under different TADA settings: open taxonomy, coarse-to-fine taxonomy, and partially-overlapping taxonomy. Our framework outperforms previous state-of-the-art by a large margin, while capable of adapting to target taxonomies
ATLAS Fast Physics Monitoring: TADA
No full textThe ATLAS Experiment at the LHC is recording data from proton-proton collisions with 13 TeV center-of-mass energy since spring 2015. The collaboration is using a fast physics monitoring framework (TADA) to automatically perform a broad range of fast searches for early signs of new physics and to monitor the data quality across the year with the full analysis level calibrations applied to the rapidly growing data. TADA is designed to provide fast feedback directly after the collected data has been fully calibrated and processed at the Tier-0. The system can monitor a large range of physics channels, offline data quality and physics performance quantities nearly final analysis level object calibrations. TADA output is available on a website accessible by the whole collaboration that gets updated twice a day with the data from newly processed runs. Hints of potentially interesting physics signals or performance issues identified in this way are reported to be followed up by physics or combined performance groups. The poster reports as well about the technical aspects of TADA: the software structure to obtain the input TAG files, the framework workflow and structure, the webpage and its implementation
TaDA: Task Decoupling Architecture for the Battery-less Internet of Things
No full textWe present TaDA, a system architecture enabling efficient execution of Internet of Things (IoT) applications across multiple computing units, powered by ambient energy harvesting. Low-power microcontroller units (MCUs) are increasingly specialized; for example, custom designs feature hardware acceleration of neural network inference, next to designs providing energy-efficient input/output. As application requirements are growingly diverse, we argue that no single MCU can efficiently fulfill them. TaDA allows programmers to assign the execution of different slices of the application logic to the most efficient MCU for the job. We achieve this by decoupling task executions in time and space, using a special-purpose hardware interconnect we design, while providing persistent storage to cross periods of energy unavailability. We compare our prototype performance against the single most efficient computing unit for a given workload. We show that our prototype saves up to 96.7% energy per application round. Given the same energy budget, this yields up to a 68.7x throughput improvement
Is Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma Superior Even to Lenvatinib? A Matching-Adjusted Indirect Comparison
No full textBackground: Atezolizumab plus bevacizumab showed superior progression-free and overall survival compared to sorafenib in the IMbrave150 trial. It would therefore be useful to compare the efficacy of lenvatinib and that of atezolizumab plus bevacizumab to determine if a benefit of one therapy against the other exists. Objective: The aim of the present report was to apply a matching-adjusted indirect comparison (MAIC) to individual participant data (IPD) from patients treated with lenvatinib outside of randomized trials, to aggregate results derived from the IMbrave150 trial. Patients and methods: Data from 455 patients who received lenvatinib as first-line systemic therapy for unresectable HCC represented the present IPD. Data inclusion were adapted to those reported in the IMbrave150 trial. Results: Overall survival on atezolizumab plus bevacizumab proved to be superior to lenvatinib (log-rank: 0.001) with a hazard ratio of 0.59 (95% confidence interval 0.46–0.75). The number needed to treat ranged between seven in the first 12 months and five at the 15th month. Conclusions: The present MAIC highlights that the combination of atezolizumab plus bevacizumab is superior to lenvatinib. However, updated data or sub-analyses of the IMbrave150 trial would provide more robust estimates for such a treatment comparison
Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells [Corrigendum]
No full textTada T, Aki K, Oboshi W, Kawazoe K, Yasui T, Hosoi E. Drug Des Devel Ther. 2016;10:3099–3107. In page 3103, there is an error in Figure 3B:Read the original articl
TaDA: A logic for time and data abstraction (extended version)
No full textTo avoid data races, concurrent operations should either be at distinct times or on distinct data. Atomicity is the abstraction that an operation takes effect at a single, discrete instant in time, with linearisability being a well known correctness condition which asserts that concurrent operations appear to behave atomically. Disjointness is the abstraction that operations act on distinct data resource, with concurrent separation logics enabling reasoning about threads that appear to operate independently on disjoint resources. We present TaDA, a program logic that combines the benefits of abstract atomicity and abstract disjointness. Our key contribution is the introduction of atomic triples, which offer an expressive approach to specifying program modules. By building up examples, we show that TaDA supports elegant modular reasoning in a way that was not previously possible
High performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants
No full textAbstract Cytosine base editors (CBEs) and adenine base editors (ABEs) enable precise C-to-T and A-to-G edits. Recently, ABE8e, derived from TadA-8e, enhances A-to-G edits in mammalian cells and plants. Interestingly, TadA-8e can also be evolved to confer C-to-T editing. This study compares engineered CBEs derived from TadA-8e in rice and tomato cells, identifying TadCBEa, TadCBEd, and TadCBEd_V106W as efficient CBEs with high purity and a narrow editing window. A dual base editor, TadDE, promotes simultaneous C-to-T and A-to-G editing. Multiplexed base editing with TadCBEa and TadDE is demonstrated in transgenic rice, with no off-target effects detected by whole genome and transcriptome sequencing, indicating high specificity. Finally, two crop engineering applications using TadDE are shown: introducing herbicide resistance alleles in OsALS and creating synonymous mutations in OsSPL14 to resist OsMIR156-mediated degradation. Together, this study presents TadA-8e derived CBEs and a dual base editor as valuable additions to the plant editing toolbox
TaDA: A Logic for Time and Data Abstraction
No full textTo avoid data races, concurrent operations should either be at distinct times or on distinct data. Atomicity is the abstraction that an operation takes effect at a single, discrete instant in time, with linearisability being a well-known correctness condition which asserts that concurrent operations appear to behave atomically. Disjointness is the abstraction that operations act on distinct data resource, with concurrent separation logics enabling reasoning about threads that appear to operate independently on disjoint resources. We present TaDA, a program logic that combines the benefits of abstract atomicity and abstract disjointness. Our key contribution is the introduction of atomic triples, which offer an expressive approach to specifying program modules. By building up examples, we show that TaDA supports elegant modular reasoning in a way that was not previously possible
<em>Tada</em>, <em>kada</em>, <em>šiada</em>, <em>andai</em>, <em>idant</em>
No full textLITH. TADA, KADA, ŠIADA, ANDAI, IDANTSummaryThe author discusses the origin of the Lithuanian forms tada, kada, šiada; kadai, kadaise kadan, kadangi; andai; idant etc. and concludes the following:The Lithuanian compounds of this type are related to the corresponding Slavic and Indo-Iranian compounds. The element -d- in the Lithuanian compounds belongs to the stems of the demonstrative pronoun *do/*de (OP din, dīgi) as the same element in OInd. tadā́, kadā́, yadā́. The element -g- in the Slavic and Baltic compounds (OCS togda, Russ. тогда, OPol. tegdy, Czech, tehda etc., Lith. tagačiaus, tagatės, Latv. tagad) could be reconstructed from the particle *go (i. e. the one related to Slavic же, OInd. gh, ha, Gk. γε, γα, Goth, -k in mi-k "me")
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