17,761 research outputs found
La historia del derecho romano de Castillejo. A propósito de su reimpresión.
No full textLa autora aborda el estado de la enseñanza del derecho romano en el primer tercio del siglo XX en las facultades de derecho de España y su relación con otros países occidentales. Toma como pretexto para sus notas la reedición de la histona del derecno
romano publicada en 1935 por Castillejo.The author describes the standing of Roman law teaching in Spanish law schools during the first part of the XX century and how it relates with its teachig in other western countries. She bases her discussion of this topic on a new edition ot Castillejo
1935 book, The History of Román Law.Publicad
Sergio Romano, “Putin e la riconstruzione della grande Russia”
No full textEn "Putin y la reconstrucción de la Gran Rusia", Sergio Romano descifra los elementos que han ido configurando personalidad política del dirigente ruso que se está convirtiendo quizá en el principal protagonista de los cambios geopolíticos en nuestra época, de Sergio Romano, por Pablo T. Martín. Longanesi Ed., Milán, 2016, 160 pág
Aspects of the Romano-British landscape around holme on Spalding moor, east Yorkshire
No full textAn examination was undertaken of the nature and extent of Romano-British settlement and industry in the context of the landscape around Holme on Spalding Moor. An environmental reconstruction of the study area was made, showing it to be marginal, low lying and prone to wetness. The most suitable land for exploitation were the ridges of Aeolian sands. Systematic field survey over an 8 x 8 km square, together with cropmark evidence showed that site distribution was closely related to soil type, watercourses and other environmental constraints. A total of 106 Romano-British kiln and settlement sites, 49 sites with iron working or manufacture and several with evidence for glass working were discovered from fieldwalking, examination of museum collections and archives and excavations. Worked flints and stone axes showed that there had been activity on the sand ridges near to watercourses since the Neolithic. The data suggests that settlement was intensified during the later Iron Age with iron working and manufacture being undertaken especially near the dendritic creek system in which the Hasholme Iron Age log boat sank. The Romano-British pottery industry seems to have built up around the same creek system, which provided a means of distribution to Shiptonthorpe, Brough and other Romano-British settlements further afield. Fabric and form analysis of local wares when compared with pottery of known date showed that production began in the later 2nd century A.D., reaching a peak in the mid fourth.Clay was plentiful and managed woodland may have provided fuel for furnaced based industries. Settlement types showed little change from the late Iron Age, but followed developments paralleled elsewhere, with some degree of Romanisation. Marine flooding did not cause the decline of industry and settlement in the area as has been previously suggested. It is possible that these settlements formed the basis of the hamlets within the parish of Holme on Spalding Moor, although continuity has yet to be proved
Ancient DNA study of the remains of putative infanticide victims from the Yewden Roman villa site at Hambleden, England
No full textPrevious analysis of the perinatal infant burials from Romano-British Yewden villa, Hambleden, indicated the practice of infanticide at that site. We attempted to determine whether this practice was specifically targeted at one sex or other by determining the sex of the infants using analysis of fragments of the amelogenin gene. We also analysed mtDNA in order to shed light on aspects of kinship. Thirty-three infants were analysed, and sex was successfully identified in 12. Seven were female, five male. No two infants shared identical mtDNA polymorphisms, indicating that all came from different mothers. Taken together with previous DNA results from perinatal remains from Romano-British sites where infanticide has been identified, they provide no evidence that manipulation of the sex ratio was a motivation for infanticide in Roman Britai
Reati contro la persona, Tomo III, Reati contro la libertà individuale, a cura di B. Romano, nel Trattato di diritto penale, diretto da C.F. Grosso-T. Padovani-A. Pagliaro, Giuffrè, Milano, 2016.
No full textL'opera fa parte di un Trattato di diritto penale composto da venti volumi, che coprono sia la parte generale che la parte speciale del codice penale ed alcuni settori extracodicistici
Il diritto penale nel canone di Mario Romano
No full textThis paper deals with the extension and the extraordinary scientific value of the works written by a great Master in Criminal Law, such as Mario Romano. The Author briefly presents some of the most relevant contributions given by Professor Mario Romano to the Criminal Science, first of all his "Commentario sistematico del codice penale" (Systematic Commentary on the penal code), a unique work. Finally, the paper talks about some topics which have been developed inside the work "Studi in onore di Mario Romano" (Studies in Honour of Mario Romano)
Deliberation and journalism
No full textThe first chapter in 'International Journalism and Democracy' re-examines current ideas about the role of journalism in promoting democracy, introducing the concept of "deliberative journalism". 'Deliberation and Journalism' lists the ways in which journalists can assist deliberation and politics in communities around the world. The chapter defines deliberation as a specific form of conversation that precedes and promotes decision-making and action by members of a community. The author recognises the difficulty of engaging in deliberation in communities that are divided by different interests, identities, backgrounds, resources and needs. She provides examples of strategies that journalists can use to encourage inclusive and productive deliberation in the face of community diversity.\ud
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The chapter introduces examples of types of deliberative journalism that have emerged around the globe. These include strategies that have been sometimes been labeled as public journalism, civic journalism, peace journalism, development journalism, citizen journalism, the street press, community journalism, environmental journalism, and social entrepreneurism. The chapter also includes models of journalism that have not yet been given any particular name. Although the book identifies problems surrounding the theory and practice of these forms of journalism, the author notes that this is to be expected. Most models of deliberative journalism are relatively new, with none being more than a few decades old. The author concludes that resolution of these problems will only occur incrementally
Reati contro la persona, Tomo III, Reati contro la libertà individuale, a cura di B. Romano, nel Trattato di diritto penale, diretto da C.F. Grosso-T. Padovani-A. Pagliaro, Giuffrè, Milano, 2016, pp. 235-321.
No full textTrattazione, in chiave sistematica, dei delitti contro l'autodeterminazione sessuale
The emerging role of FKBP51 in melanoma: characterization of a promising molecular target for innovative therapies
No full textMelanoma is a malignant skin cancer with high metastatic potential. The
number of melanoma cases worldwide is increasing faster than any other cancer. The prognosis is bad in the advanced stages of the disease due to resistance to conventional anti-cancer treatments. Patients diagnosed with advanced stage melanoma continue to pose a significant challenge for clinicians. Although many therapeutic regimens for metastatic melanoma have been tested, very few achieve response rates greater than 25%. There is much hope for targeted therapies and promising agents include those that act on apoptosis-regulating molecules. Very recently, we have identified that an immunophilin, namely FK506 binding protein (FKBP) 51 controls response of melanoma to DNA damaging agents, such as anthracyclines compounds. The aim of this study was to investigate the possible role of FKBP51 in the control of response to ionizing radiation (IR) in malignant melanoma. FKBP51-silenced cells showed reduced clonogenic potential after irradiation compared with non-silenced cells. After IR, we observed apoptosis in FKBP51-silenced cells and autophagy in non-silenced cells. FKBP51 was required for the activation of Rx-induced NF-kappaB, which in turn inhibited apoptosis by
stimulating X-linked inhibitor of apoptosis protein and promoting authophagymediated Bax degradation. Using a tumor-xenograft mouse model, the in vivo pretreatment of tumors with FKBP51-siRNA provoked massive apoptosis after irradiation. Immunohistochemical analysis of 10 normal skin samples and 80 malignant cutaneous melanomas showed that FKBP51 is a marker of melanocyte malignancy, correlating with vertical growth phase and lesion thickness. Moreover, we provided evidence that FKBP51 targeting radiosensitizes cancer stem/initiating cells. Finally, we expanded the study to other types of cancer, including ovarian, pancreatic, prostate, colon, breast and lung cancer and found a strong correlation between the protein expression and malignity of the tumoral lesions. In conclusion, our study identifies a possible molecular target for radiosensitizing therapeutic strategies against malignant melanoma and a potential novel tumoral biomarker
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