874 research outputs found

    GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database

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    Kleinbölting N, Huep G, Klotgen A, Viehöver P, Weisshaar B. GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database. Nucleic Acids Research. 2012;40(D1):D1211-D1215.T-DNA insertion mutants are very valuable for reverse genetics in Arabidopsis thaliana. Several projects have generated large sequence-indexed collections of T-DNA insertion lines, of which GABI-Kat is the second largest resource worldwide. User access to the collection and its Flanking Sequence Tags (FSTs) is provided by the front end SimpleSearch (http://www.GABI-Kat.de). Several significant improvements have been implemented recently. The database now relies on the TAIRv10 genome sequence and annotation dataset. All FSTs have been newly mapped using an optimized procedure that leads to improved accuracy of insertion site predictions. A fraction of the collection with weak FST yield was re-analysed by generating new FSTs. Along with newly found predictions for older sequences about 20 000 new FSTs were included in the database. Information about groups of FSTs pointing to the same insertion site that is found in several lines but is real only in a single line are included, and many problematic FST-to-line links have been corrected using new wet-lab data. SimpleSearch currently contains data from ∼71 000 lines with predicted insertions covering 62.5% of the 27 206 nuclear protein coding genes, and offers insertion allele-specific data from 9545 confirmed lines that are available from the Nottingham Arabidopsis Stock Centre

    Poetic metaphor in literary discourse devoted to war ("War of the beasts and the animals" by Maria Stepanova)

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    Maria Stiepanowa (1972) - rosyjska pisarka, eseistka i dziennikarka, za swój wyjątkowy talent literacki była szeroko nagradzana w Rosji i Europie. W roku 2015 opublikowała poemat Wojna bestii i zwierząt, będący poetycką reakcją na historyczne wydarzenie, jakim była aneksja Krymu przez Rosję (2014). Wyszukana poetyka i skomplikowana obrazowość utworu kryje w sobie opis odwiecznej historii starć i konfliktów dwóch narodów (Rosji i Ukrainy) mówiących wspólnym językiem. W artykule pragnę przyjrzeć się, w jaki sposób nowatorski język poetycki (metaforyka) Marii Stiepanowej ukazuje okrutne obrazy wojny i czy jej twórczość jest w stanie stać się „nowym głosem o wojnie” wypowiadanym w języku rosyjskim.Maria Stepanova (1972) is a Russian writer, essayist, and journalist, who is recognized in Russia and Europe for her outstanding literary gift. In 2015 she published a poem entitled War of the Beasts and the Animals, her poetic response to the annexation of Crimea by the Russian Federation (2014). The complicated poetics and convoluted imagery of this work describe an age-long history of conflicts between two nations (Russians and Ukrainians) being, as a matter of fact, a “civil war” (quote from the poem War of the Beasts…). In the paper, the author discusses how the innovative poetic language (metaphors) of Maria Stepanova processes the cruel images of war and tries to find the answer: whether it can become “a new voice in the war” spoken in Russian.Мария Степанова (1972) - российская писательница, публицистка и журналистка, за исключительный литературный талант получившая широкое признание в России и Европе. В 2015 году опубликовала поэму  Война зверей и животных, которая является поэтической реакцией на историческое событие, каким оказалась аннексия Крыма Россией в 2014 году. В сложной поэтике и образности произведения кроется описание извечной истории столкновений и конфликтов двух народов (России и Украины), фактически борющихся в одной общей гражданской войне и говорящих на одном и том же языке. В статье мне хотелось бы посмотреть, как новаторский поэтический язык (метафорика) Марии Степановой перевоплощает жестокие образы войны и способен ли он оказаться «новым голосом о войне», выраженным на русском языке

    La polvere della memoria. Osservazioni sul libro di M. Stepanova "Pamjati pamjati"

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    La polvere della memoria. Osservazioni sul libro di M. Stepanova Pamjati pamjati Il libro di M. Stepanova, Pamjati pamjati (2017), definito dai critici “il miglior romanzo russo degli ultimi anni”, è entrato dopo pochi giorni dalla sua pubblicazione nelle classifiche dei libri più ven-duti, dando grande notorietà a una poetessa e saggista, nota e apprezzata nei circoli intellettuali pro-gressisti. L’opera si basa sul desiderio dell’autrice di raccogliere e salvare i ricordi e le testimonian-ze dei propri cari sullo sfondo della grande storia. Metaromanzo, storia d’amore, resoconto di viag-gio, riflessione sulla fotografia o tutte queste cose insieme, in Pamjati pamjati, il fenomeno della memoria si sovrappone ad altri temi, diventa ampio e molteplice: la memoria e la storia, la memoria e la catastrofe, la memoria e il suono, la memoria e gli oggetti, la memoria e l’etica. L’autrice porta alla luce i suoi morti e sono loro che la aiuteranno a cambiare il suo linguaggio. A scrivere quello che è in sostanza un necrologio alla memoria la aiuta uno degli autori che le sono più vicini, W. G. Sebald, i cui libri, a prescindere dal tema trattato, sono sempre scritti dalla parte dei morti. Partendo dall’idea di scrivere la storia della propria famiglia ebrea – russa – europea, composta da medici, architetti, bibliotecari, ragionieri e ingegneri che aspirano a condurre una vita tranquilla in un mondo violento e incivile, l’autrice tocca il problema della memoria del passato, dei piccoli e grandi avvenimenti del XX secolo, e di come essi possano sopravvivere nella memoria personale del singolo. L’ebraismo costituisce uno dei punti focali della narrazione, segna il destino dei personaggi anche se non tragicamente, perché quasi tutti riescono a sfuggire all’olocausto, al terrore staliniano. Non di meno la fragilità e l’insignificanza delle loro vite appaiono vulnerabili. Diviso in tre parti, la prima di nove capitoli, la seconda di dieci e la terza di quattro, il libro mescola nelle prime due parti lettere di parenti, documenti, che conservano le loro voci. Intorno alle lettere, ci sono fotografie, oggetti quotidiani che l’autrice non si limita a descrivere al lettore, bensì mostra, trascrive, ingloba nel suo testo, perché ha sfiducia nelle immagini, nei selfi che pretendono di ripro-durre la vita senza riuscirci. La definizione “romance”, romanza, che leggiamo in copertina caratte-rizza perfettamente l’opera, tanto che alla fine Stepanova confessa a se stessa di aver dedicato il suo tempo non ad un’occupazione rispettabile, a una ricerca o a uno studio, bensì a un romanzo familia-re “freudiano”, a una “romanza sentimentale sul passato”.The Dust of Memory. A few remarks on M. Stepanova’s book Pamjati pamjati The present article deals with M. Stepanova’s book Post-Memory published in 2017 with great suc-cess, a book which has no analogues not only in Russian but also in world literature. A meta-novel, a great literary reconstruction, which has created a whole new genre and sounds the relation be-tween memory, time, and history. Stepanova had the idea of this writing at ten or eleven years. The project started as an exploration of how our memory works. When she started working on the book, she meant linear narrative —a sto-ry of search and finding. Go there, go here, find out, describe. It seemed her then that a large part of the hiatus and failures that have been family history will be easy to fill in accurate knowledge; but it turned out that the story is mostly from hiatus and is neither to find nor to make up for really any-thing. Only when she began to disassemble the family archive, she found, among other things, let-ters, photos, horoscopes, childhood souvenirs, things that the author examines in astonishment. Who were these people who travelled all throughout Europe yet lived in Russia? Who did their best to remain anonymous and who made little effort to make history seem interesting? But it is precise-ly the unspectacular nature of the find which turns the author’s research in the Russian context into something new: «Everyone else had a family made up of people participating in history; mine was made up only of their tenants». Destined to become victims of persecution and repression, they all still managed to survive the 20th century. How was that possible? This is the question and point of departure for Marija Stepanova’s first great work of prose. In dialogue with W.G. Sebald, imbued with a passion for thought and a wonderfully soft, poetic voice derived from sensual as well as intellectual observations, Stepanova assembles her found pieces into a panorama of an entire age. At its heart lives a large family of doctors, architects, librar-ians, accountants, and engineers, unheroic individuals who did not attach themselves to any great project but who in uncivilized, violent times attempted to live quiet, civilized lives

    Implementation of potential of the transdisciplinary approaches in economic studies

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    The relevance of the researched problem is caused by the increasing interest in using potential of transdisciplinary approaches, and mathematical methods, which include the game theory in analysis of public and economic processes. The aim of the article is studying a possibility of implementation of the transdisciplinary approaches in economic researches. The leading approach is institutional and evolutionary, which allows to reveal such tendencies of relationship development and interrelations of individuals that remain hidden and implicit. It also allows to receive new and quite unexpected important results, significant for practice. In the article the hypothesis is proved. According to it, innovations, its generation and autopoiesis itself are structural units. In the innovative environment it assumes various forms. The materials of the article can be useful for development of the theory of the system analysis, and also when developing macroeconomic forecasts of social and economic development. © 2016 Stepanova et al

    Implementation of potential of the transdisciplinary approaches in economic studies

    No full text
    The relevance of the researched problem is caused by the increasing interest in using potential of transdisciplinary approaches, and mathematical methods, which include the game theory in analysis of public and economic processes. The aim of the article is studying a possibility of implementation of the transdisciplinary approaches in economic researches. The leading approach is institutional and evolutionary, which allows to reveal such tendencies of relationship development and interrelations of individuals that remain hidden and implicit. It also allows to receive new and quite unexpected important results, significant for practice. In the article the hypothesis is proved. According to it, innovations, its generation and autopoiesis itself are structural units. In the innovative environment it assumes various forms. The materials of the article can be useful for development of the theory of the system analysis, and also when developing macroeconomic forecasts of social and economic development. © 2016 Stepanova et al

    Regional Control Over Compliance with the Requirements of the Legislation of the Russian Federation in the Field of Children’s Recreation and Health

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    This article discusses issues related to the emergence of a new type of control from January 1, 2017, namely, regional control over compliance with the requirements of the legislation of the Russian Federation in the field of organization of recreation and rehabilitation of children. The subjects of control are identified. It is noted that the lack of a clear wording of the subject of control impedes the effective implementation of the activities of its entities and creates the possibility of double control of children's recreation organizations and their recovery by officials of various public authorities. The author formulated a proposal to eliminate a gap in the legislation related to the absence of a Code of the Russian Federation on Administrative Offense, which provides for administrative liability for violation of the requirements of the legislation of the Russian Federation in the field of organization of recreation and recreation for children

    Економічна політика Російської імперії як фактор розвитку промислового винокуріння в Україні в першій половині XIX століття

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    The article is devoted to the analysis of the legislation of the Russian empire in the field of the distillery industry in the first half of the XIX century. The object of research is the socio-economic factors of the formation of the distillery industry. The subject of the study is the measures of state power of the Russian empire in the field of distilling as the main factor in its development. Тhe link between government measures and the development of the distillery industry has been established. The effectiveness of the state economic policy of the Russian empire in the field of distillery industry is investigated. The factors of functioning of enterprises for the production of alcohol and vodka are determined. The assessment of the activity of tax intermediaries between the state and industrialists is given. An author reached to the conclusion in relation to the necessity of appeal to historical experience of overcoming of the crisis phenomena in the economy.Стаття присвячена аналізові законодавства Російської імперії в галузі винокурної промисловості в першій половині XIX століття. Визначено фактори функціонування підприємств з виробництва спирту та горілки. Досліджено економічні заходи державної влади та їх вплив на становлення винокурної індустрії. Встановлено зв’язок між змінами в законодавстві та розвитком галузі. Дається оцінка діяльності податкових посередників між державою та промисловцями

    ПУБЛІЦИСТИЧНА СПАДЩИНА ОЛЕСЯ ДОСВІТНЬОГО

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    This paper was conceived as a critical examination of the journalistic works by Oles Dosvitniy. Stressing theimportance of the writer’s journalistic works in tracing back the sources of his literary creativity, the author givesmuch attention to the social, political and cultural matters which are at issue in O. Dosvitniy’s articles, pointsout the specifi cs of their genre, thereby classifying them into several groups and subgroups, and also takesnotice of the modes of dialogue with the reader as well as of polemic, stylistic and rhetoric devices. A specialemphasis is made on O. Dosvitniy’s contributions to the literary discussion in 1925-28.Стаття становить собою спробу критичного розгляду публіцистичної спадщини О.Досвітнього, яка насьогодні маловивчена. Акцентуючи важливість дослідження публіцистики письменника для простеженнявитоків його художньої творчості, авторка приділяє значну увагу соціально-політичній і культурнійпроблематиці його статей, їхній жанровій специфіці, розділяючи їх відповідно на кілька груп та підгруп, атакож засобам побудови діалогу із читачем, полемічним і стилістичним прийомам. Окремо розглядаєтьсяпитання участі О.Досвітнього в літературній дискусії 1925 – 1928 рр

    Організація цукрового виробництва в Чернігівській губернії в роки Першої світової війни

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    The article is devoted to the analysis of the sugar industry in the Chernihiv province in the period from the beginning of the First World War to the October Revolution. A comparative analysis of the dynamics of the sugar industry in the prewar and war periods was carried out. The regional features of the sugar industry development of Chernihiv province during the years of the First World War were determined. The factors of appearance of crisis tendencies in the industry are defined and attention is focused on the economic policy of the government. The activity of the monopolistic association of sugar entrepreneurs was explored. The directions of activity of specialized government agencies that privided the functioning of sugar factories in wartime are determined. An author reached to the conclusion in relation to the necessity of appeal to historical experience of overcoming of the crisis phenomena in the economy. For an analysis of the question the regional and statistical collections of the second half of the ХІХth – the beginning of the ХХth century were used.Стаття присвячена аналізові стану цукрової промисловості Чернігівської губернії в період від початку Першої світової війни до Жовтневого перевороту. Визначені фактори появи кризових тенденцій у галузі та акцентовано увагу на економічній політиці уряду. Зроблено порівняльний аналіз динаміки розвитку виробництва цукру у передвоєнний і воєнний час. Відзначено регіональні особливості розвитку цукрової промисловості в Чернігівській губернії. Особливу увагу приділено політиці уряду щодо стимулювання цукрового виробництва. Розкрито питання щодо виникнення цукрових монополій наприкінці ХІХ – на початку ХХ ст

    THE PUBLIC MEZZANINE CAPITAL: FEASIBILITY STUDY

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    A growing number of financial institutions are unable to raise the required amount of equity and have to raise their own funds by means of public mezzanine. If these problems continue, the role of hybrids may become more significant, as they may be considered as a replacement of common equity for the purpose of counter-cyclical buffers, capital surcharges and so on. Thus, the importance of mezzanine capital for the financial system is already established and has a potential for further growth, while regulatory aspects and risk assessment of these relatively new instruments remain unsolved. In the article, the author analyses key regulatory concerns of Basel Accords in regards to mezzanine instruments, assesses the methodology of rating agencies to evaluate the risks incorporated in hybrid securities and compares the risk profiles of traditional convertible and recently developed contingent convertible bonds. The results articulate that measures applied by both Basel Committee members and rating agencies (Fitch, Moody’s, etc.) are not sufficient to manage risks incorporated in hybrid securities. The latter may contribute to the growth of financial failures we have observed in recent years
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