79 research outputs found
Immigrants’ housing in the housing market in Russia: from the results of sociological questionnaire
No full textThe study is based on the results of an original sociological survey conducted in 25 cities of Russia from June 2017 to March 2018 by the author. This paper focuses especially on labour immigrants from Central Asia, Ukraine, Belarus and Caucasus regions into Russia. This paper argues the following points; first, the correlation between the demographic movements and regional rental housing fee in Russia, second, the multi-layered structure and its informality of Russian housing market, finally, the relation between labour migrants’ housing condition and labour productivity. In the conclusion, the author points that the Russian housing market is segregated from this research results. Migrant’s housing deals are possibly the origin or bottom of the housing market. Their activity would move the regional housing rental market. However, some of their deals also seem to be invisible in the official housing statistics, that is to say, taking place in the informal housing market. This regards as one of characters, which Russian rental housing market has. It would be hurdle for foreign direct investor, which would invest into Russian market. In addition, the quality of immigrants’ housing condition is too low to support their labour productivity sustainably. We need to consider the improvement even for labour immigrants and the creation of more open housing market in Russia
Construction of fluctuation load model and dynamic simulation with LFC control of DC power system and frequency converter interconnection
No full text
Shin-gi-tai as a guiding principle in Kōdōkan jūdō : yet, another example of historical reinvention?
No full textJudo national governing bodies in recent years through slogans, posters, cartoons, and web site information have attempted to reignite their members’ appreciation for a judo morality constructed on Japanese bushido. Similarly, several judo federations actively promote ‘shin-gi-tai’ (mind-technique-body) as a guiding principle for rank promotions and conduct allegedly in association with Kano Jigoro’s philosophy. Using translation, critical and heuristic analysis of relevant original historical Japanese sources, it is the purpose of this paper to investigate the origin, etymology and justification of shin-gi-tai as a pre-existing principle in Kodokan judo. Our results show that shin-gi-tai was first used in judo by Michigami Haku while teaching in Shanghai in the 1940s. After his arrival in France in 1953, the concept was introduced and distributed within the Western judo world. However, Michigami was not the original author. It was on the island of Kyushu, from where Michigami hailed, that the term shin-gi-tai appears to have been first used in the Heiho shingitai oboegaki (Memorandum on military arts and mind-technique-body), a text authored by Toyoda Masanaga, an 18th century Niten ichi-ryu heiho swordsman influenced by Miyamoto Musashi. A similar term, shinkitai, later entered sumo through the Yoshida family, also active in Kyushu, who became responsible for the administration of sumo in the late Meiji period. Michigami as a young man had practiced both kendo and sumo. There is no link between Kano Jigoro and shin-gi-tai. While it is acceptable to use shin-gi-tai or any other legitimate meme in coaching athletes, asserting that it represents a fundamental principle that guides rank promotions and ethics in judo is nothing but historical reinvention that lacks any basis.Los órganos nacionales rectores del judo han intentado en los últimos años, a través de eslóganes, carteles, dibujos animados e informaciones en páginas web, reavivar entre sus miembros el aprecio por la moral judo, construida sobre el bushido japonés. Asimismo, algunas federaciones de judo promueven de forma activa el “shin-gi-tai” (mente-técnica-cuerpo) como principio guía para los ascensos de grado y la conducta del practicante, supuestamente en asociación con la filosofía de Kano Jigoro. Utilizando la traducción, el análisis crítico y heurístico de fuentes japonesas históricas, originales y relevantes, este trabajo tiene el propósito de investigar el origen, la etimología y la justificación del shin-gi-tai como principio preexistente en el judo Kodokan. Los resultados muestran que el shin-gi-tai fue utilizado por primera vez en el judo por Michigami Haku mientras enseñaba en Shanghái en la década de 1940. Tras su llegada a Francia en 1953, el concepto fue introducido y difundido en el judo occidental. Sin embargo, Michigami no fue el autor original. Fue en la isla de Kyushu, de donde procedía Michigami, donde el término shin-gi-tai parece haber sido utilizado por primera vez en el Heiho shingitai oboegaki (Memorándum sobre las artes militares y la mente-técnica-cuerpo), un texto cuyo autor fue Toyoda Masanaga, un espadachín heiho de la Niten ichi-ryu del siglo XVIII influenciado por Miyamoto Musashi. Un término similar, shinkitai, entró más tarde en el sumo a través de la familia Yoshida, también activa en Kyushu, que se hizo responsable de la administración del sumo a finales del periodo Meiji. Michigami, de joven, había practicado tanto el kendo como el sumo. No existe ningún vínculo entre Kano Jigoro y el shin-gi-tai. Si bien es aceptable usar el término o cualquier otro meme legítimo en el entrenamiento de atletas, afirmar que representa un principio fundamental que guía los ascensos de rango y la ética en el judo no es más que una reinvención histórica que carece de toda base.Os órgãos governamentais nacionais de judo nos últimos anos, por meio de slogans, pôsteres, desenhos animados e informações de sites, tentaram reacender a apreciação de seus membros por uma moralidade judo construída no bushido japonês. Do mesmo modo, várias federações de judo promovem ativamente o “shin-gi-tai” (mente-técnica-corpo) como princípio orientador das promoções de categoria e da conduta, alegadamente em associação com a filosofia de Kano Jigoro. Utilizando a tradução, a análise crítica e heurística de fontes históricas japonesas originais relevantes, o objetivo deste artigo é investigar a origem, a etimologia e a justificação do shin-gi-tai como um princípio pré-existente em Kodokan judo. Os nossos resultados mostram que o shin-gi-tai foi usado pela primeira vez no judo por Michigami Haku enquanto ensinava em Xangai na década de 1940. Após a sua chegada a França em 1953, o conceito foi introduzido e distribuído no judo ocidental. No entanto, Michigami não foi o autor original. Foi na ilha de Kyushu, de onde Michigami era originário, que o termo shin-gi-tai parece ter sido usado pela primeira vez no Heiho shingitai oboegaki (Memorando sobre artes militares e mente-técnica-corpo), um texto da autoria de Toyoda Masanaga, um espadachim heiho de Niten ichi-ryu do século XVIII influenciado por Miyamoto Musashi. Um termo semelhante, shinkitai, entrou mais tarde no sumo através da família Yoshida, também ativa em Kyushu, que se tornou responsável pela administração do sumo no final do período Meiji. Michigami, quando jovem, praticou tanto kendo quanto sumo. Não existe qualquer ligação entre o Kano Jigoro e o shin-gi-tai. Embora seja aceitável utilizar o shin-gi-tai ou qualquer outro meme legítimo no treino de atletas, afirmar que representa um princípio fundamental que orienta as promoções de categoria e a ética no judo não passa de uma reinvenção histórica sem qualquer fundamento.Judo national governing bodies in recent years through slogans, posters, cartoons, and web site information have attempted to reignite their members’ appreciation for a judo morality constructed on Japanese bushido. Similarly, several judo federations actively promote ‘shin-gi-tai’ (mind-technique-body) as a guiding principle for rank promotions and conduct allegedly in association with Kano Jigoro’s philosophy. Using translation, critical and heuristic analysis of relevant original historical Japanese sources, it is the purpose of this paper to investigate the origin, etymology and justification of shin-gi-tai as a pre-existing principle in Kodokan judo. Our results show that shin-gi-tai was first used in judo by Michigami Haku while teaching in Shanghai in the 1940s. After his arrival in France in 1953, the concept was introduced and distributed within the Western judo world. However, Michigami was not the original author. It was on the island of Kyushu, from where Michigami hailed, that the term shin-gi-tai appears to have been first used in the Heiho shingitai oboegaki (Memorandum on military arts and mind-technique-body), a text authored by Toyoda Masanaga, an 18th century Niten ichi-ryu heiho swordsman influenced by Miyamoto Musashi. A similar term, shinkitai, later entered sumo through the Yoshida family, also active in Kyushu, who became responsible for the administration of sumo in the late Meiji period. Michigami as a young man had practiced both kendo and sumo. There is no link between Kano Jigoro and shin-gi-tai. While it is acceptable to use shin-gi-tai or any other legitimate meme in coaching athletes, asserting that it represents a fundamental principle that guides rank promotions and ethics in judo is nothing but historical reinvention that lacks any basis.Los órganos nacionales rectores del judo han intentado en los últimos años, a través de eslóganes, carteles, dibujos animados e informaciones en páginas web, reavivar entre sus miembros el aprecio por la moral judo, construida sobre el bushido japonés. Asimismo, algunas federaciones de judo promueven de forma activa el “shin-gi-tai” (mente-técnica-cuerpo) como principio guía para los ascensos de grado y la conducta del practicante, supuestamente en asociación con la filosofía de Kano Jigoro. Utilizando la traducción, el análisis crítico y heurístico de fuentes japonesas históricas, originales y relevantes, este trabajo tiene el propósito de investigar el origen, la etimología y la justificación del shin-gi-tai como principio preexistente en el judo Kodokan. Los resultados muestran que el shin-gi-tai fue utilizado por primera vez en el judo por Michigami Haku mientras enseñaba en Shanghái en la década de 1940. Tras su llegada a Francia en 1953, el concepto fue introducido y difundido en el judo occidental. Sin embargo, Michigami no fue el autor original. Fue en la isla de Kyushu, de donde procedía Michigami, donde el término shin-gi-tai parece haber sido utilizado por primera vez en el Heiho shingitai oboegaki (Memorándum sobre las artes militares y la mente-técnica-cuerpo), un texto cuyo autor fue Toyoda Masanaga, un espadachín heiho de la Niten ichi-ryu del siglo XVIII influenciado por Miyamoto Musashi. Un término similar, shinkitai, entró más tarde en el sumo a través de la familia Yoshida, también activa en Kyushu, que se hizo responsable de la administración del sumo a finales del periodo Meiji. Michigami, de joven, había practicado tanto el kendo como el sumo. No existe ningún vínculo entre Kano Jigoro y el shin-gi-tai. Si bien es aceptable usar el término o cualquier otro meme legítimo en el entrenamiento de atletas, afirmar que representa un principio fundamental que guía los ascensos de rango y la ética en el judo no es más que una reinvención histórica que carece de toda base.Os órgãos governamentais nacionais de judo nos últimos anos, por meio de slogans, pôsteres, desenhos animados e informações de sites, tentaram reacender a apreciação de seus membros por uma moralidade judo construída no bushido japonês. Do mesmo modo, várias federações de judo promovem ativamente o “shin-gi-tai” (mente-técnica-corpo) como princípio orientador das promoções de categoria e da conduta, alegadamente em associação com a filosofia de Kano Jigoro. Utilizando a tradução, a análise crítica e heurística de fontes históricas japonesas originais relevantes, o objetivo deste artigo é investigar a origem, a etimologia e a justificação do shin-gi-tai como um princípio pré-existente em Kodokan judo. Os nossos resultados mostram que o shin-gi-tai foi usado pela primeira vez no judo por Michigami Haku enquanto ensinava em Xangai na década de 1940. Após a sua chegada a França em 1953, o conceito foi introduzido e distribuído no judo ocidental. No entanto, Michigami não foi o autor original. Foi na ilha de Kyushu, de onde Michigami era originário, que o termo shin-gi-tai parece ter sido usado pela primeira vez no Heiho shingitai oboegaki (Memorando sobre artes militares e mente-técnica-corpo), um texto da autoria de Toyoda Masanaga, um espadachim heiho de Niten ichi-ryu do século XVIII influenciado por Miyamoto Musashi. Um termo semelhante, shinkitai, entrou mais tarde no sumo através da família Yoshida, também ativa em Kyushu, que se tornou responsável pela administração do sumo no final do período Meiji. Michigami, quando jovem, praticou tanto kendo quanto sumo. Não existe qualquer ligação entre o Kano Jigoro e o shin-gi-tai. Embora seja aceitável utilizar o shin-gi-tai ou qualquer outro meme legítimo no treino de atletas, afirmar que representa um princípio fundamental que orienta as promoções de categoria e a ética no judo não passa de uma reinvenção histórica sem qualquer fundamento.A
T Cell-Association of Carboxy-Terminal Dendrimers with Different Bound Numbers of Phenylalanine and Their Application to Drug Delivery
No full textT cells play important roles in various immune reactions, and their activation is necessary for cancer immunotherapy. Previously, we showed that polyamidoamine (PAMAM) dendrimers modified with 1,2-cyclohexanedicarboxylic acid (CHex) and phenylalanine (Phe) underwent effective uptake by various immune cells, including T cells and their subsets. In this study, we synthesized various carboxy-terminal dendrimers modified with different bound numbers of Phe and investigated the association of these dendrimers with T cells to evaluate the influence of terminal Phe density. Carboxy-terminal dendrimers conjugating Phe at more than half of the termini exhibited a higher association with T cells and other immune cells. The carboxy-terminal Phe-modified dendrimers at 75% Phe density tended to exhibit the highest association with T cells and other immune cells, which was related to their association with liposomes. A model drug, protoporphyrin IX (PpIX), was encapsulated into carboxy-terminal Phe-modified dendrimers, which were then used for drug delivery into T cells. Our results suggest the carboxy-terminal Phe-modified dendrimers are useful for delivery into T cells
ChemInform Abstract: HF—Pyridine: A Versatile Promoter for Monoacylation/Sulfonylation of Phenolic Diols and for Direct Conversion of t‐Butyldimethylsilyl Ethers to the Corresponding Acetates.
No full textDevelopment of a multi-segmented linear Paul trap and reduction of ion micromotion towards quantum-state manipulation
No full textNovel mutation in the ALPL gene with a dominant negative effect in a Japanese family
No full textIntroduction Hypophosphatasia (HPP) is caused by mutations in the ALPL gene encoding tissue nonspecific alkaline phosphatase (TNSALP) and inherited in either an autosomal recessive or autosomal dominant manner. It is characterized clinically by defective mineralization of bone, dental problems, and low serum ALP levels. In the current report, we demonstrate a novel mutation in the ALPL gene (c.244G > A p.Gly82Arg) in a Japanese family with low serum ALP levels. Materials and methods The ALPL gene analysis using hybridization capture-based next-generation sequencing was performed. The expression plasmids of the wild type and mutated TNSALP were introduced into COS-7 cells. The enzymatic activity of ALP in the cell lysates was measured using p-nitrophenylphosphate as a substrate. Results TNSALP with the novel ALPL mutation (c.244G > A p.Gly82Arg) completely lost its enzymatic activity and suppressed that of wild-type TNSALP, corroborating its dominant negative effect. The diagnosis of autosomal dominant HPP was confirmed in three members of the family. Conclusion Our approach would help to avoid the inappropriate use of bone resorption inhibitors for currently mis- or under-diagnosed HPP, given that the presence of further, yet undetected mutations of the ALPL gene are plausible
NMR signal analysis in the large COMPASS NH target
No full textIn the large COMPASS polarized proton target the 1508 cm of irradiated granular ammonia is polarized with dynamic nuclear polarization method using 4 mm microwaves in 2.5 T eld. The nuclear polarization up to 90 - 93 % is determined with cw NMR. The properties of the observed ammonia proton signals are described and spin thermodynamics in high elds is presented. Also the second moment of the NMR line is estimated
Novel mutations in the a3 subunit of vacuolar H+-adenosine triphosphatase in a Japanese patient with infantile malignant osteopetrosis
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