349 research outputs found
Poskus predstavitve odnosa do tujejezičnih imen slovenskih podjetij v luči statistične analize
No full textForeign names of Slovene companies are one of the current issues concerning the Slovene language and culture. The author presents a pilot study, based on statistical analysis, of the attitude which the native speakers of Slovene take towards such names.V prispevku je opisan poskus predstavitve odnosa govorcev slovenskega jezika do tujejezičnih imen slovenskih podjetij v luči statistične analize. Gre za pilotsko raziskavo, ki skozi posamezne korake izbrane statistične metode podaja analizo in interpretacijo interdisciplinarno zasnovanega raziskovalnega pristopa k aktualni j ezikovnokultur ni problematiki
Poskus kvantitativnega merjenja funkcionalne pismenosti
No full textThe article discusses the attempt to provide the quantity measurement of functional literacy, carried out in the form of a questionnaire. Making use of examples, the author shows the advantages and disadvantages ascribed to the quantity measurement of functional literacy, trying to ascertain how successfully this could be implemented, and pointing out possible improvements. Because of extensive data, only the introductory illustration of such a measurement style is illustrated in the article, and some general findings concerning measurement are presented. However, neither detailed data nor findings concerning the analysis of the questionnaire are presented at this point. The author’s intention was to show the problem of designing formulae necessary for quantity measurement; in spite of their vagueness (or because of it) they are frequently still too rigid for a flexible linguistic capability. This was done on the analysis of examples from the questionnaire, especially concerning the questionnaire’s format and layout, with some other options also pointed out which were overlooked during measurement or were not foreseen by the author, although they also need to be taken into account in further study.V članku obravnavam poskus kvantitativnega merjenja funkcionalne pismenosti, ki je bilo opravljeno z anketo. Ob primerih predstavim prednosti in pomanjkljivosti kvantitativnega merjenja funkcionalne pismenosti oz. ugotavljam, koliko je to sploh mogoče uspešno opraviti ter nakažem možne izboljšave. Na tem mestu zaradi preobsežnosti podatkov predstavim le uvodni prikaz takega načina merjenja ter nakažem splošne ugotovitve v zvezi z merjenjem, ne navajam pa niti vseh natančnih podatkov, niti vseh ugotovitev, povezanih z analizo ankete. Moj namen je bil predvsem predstaviti problematiko oblikovanja formul, potrebnih za kvantitativno merjenje, ki so kljub prenekateri ohlapnosti (ali pa prav zaradi nje) še vedno prevečkrat pretoge za prožno jezikovno zmožnost. To je bilo storjeno ob analizi primerov besedil iz ankete, zlasti pa ob analizi same oblike ankete, pri čemer so bile izpostavljene še nekatere možnosti, ki so bile pri tem merjenju spregledane oz. jih nisem predvidela, a bi jih bilo potrebno pri nadaljnjem delu upoštevati
Berlinska konferenca treh internacional - poskus oblikovanja politike "enotne fronte"
No full textThe treatise deals with the fate of the "United Front" policy (an attempt of coalition formation between the Communist Parties and the Social-Democratic Parties), initiated by the Vienna International on the occasion of its foundation (February 1921). In this context the author analyses the common conference of the delegates of three lntemationals (of Bern, Vienna and Moscow) in Berlin in April 1922, trying lo find the reasons for its fiasco.Razprava obravnava usodo politike »enotne fronte« (poskus oblikovanja koalicije komunističnih partij in socialdemokratskih strank), ki jo je pobudila dunajska internacionala ob svoji ustanovitvi (februarja 1921). V tem kontekstu avtor analizira skupno konferenco delegatov treh internacional (bernske, dunajske, moskovske) v Berlinu aprila 1922 ter išče vzroke za njen neuspeh
Predictors for Anastomotic Leak, Postoperative Complications, and Mortality After Right Colectomy for Cancer: Results From an International Snapshot Audit
No full textBACKGROUND: A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking.OBJECTIVE: This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy.DESIGN: This was a snapshot observational prospective study.SETTING: The study was conducted as a multicenter international study.PATIENTS: The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients.MAIN OUTCOME MEASURES: Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method.RESULTS: Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p > 0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041).LIMITATIONS: This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors.CONCLUSIONS: Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery. See Video Abstract at http://links.lww.com/DCR/B165
El transportador de zinc: repercusiones de su polimorfismo en la diabetes tipo 2, y en las variantes tipo 1/LADA
No full textLa diabetes autoinmune resulta de una pérdida progresiva de células del islote pancreático, en donde los linfocitos T adquieren fundamental protagonismo. Es una enfermedad tejido-específica, en la cual la autoinmunidad se limita a una serie de moléculas expresadas en las células β pancreáticas. La identificación de esas moléculas, blanco del sistema inmune, proporciona información relevante acerca del mecanismo patogénico y abre el panorama para el desarrollo de futuros agentes terapéuticos. El principal autoantígeno descubierto en los últimos diez años es el transportador de zinc 8 (ZnT8). Es una proteína de 369 aminoácidos codificada por el gen SLC30A8 localizado en el cromosoma 8 en la posición q24.11. Presenta seis dominios de transmembrana y un dominio rico en histidina entre la cuarta y la quinta hélice (importante esta mención ya que es uno de los sitios conocidos a los que se une la molécula de zinc). Su principal función es la de transportar zinc desde el citoplasma de la célula beta al interior del gránulo de secreción. La ausencia experimentalmente provocada del ZnT8 en ratones knock out produce disminución de las concentraciones del catión en la célula β, generando gránulos de almacenamiento atípicos, vacíos e inmaduros y un aumento de la relación plasmática proinsulina/insulina. En efecto, el ZnT8 es la principal herramienta con la que cuenta la célula β pancreática para proveer el zinc destinado al procesamiento, maduración y almacenamiento de la insulina, y en consecuencia, presenta un rol activo en la regulación de la homeostasis de la glucosa.Fil: Figueredo, Carolina Paola. Provincia del Chaco. Clínica San Ramón; ArgentinaFil: Poskus, Edgardo. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Houssay. Instituto de Estudios de la Inmunidad Humoral "Profesor R. A. Margni"; Argentina. Provincia del Chaco. Clínica San Ramón; Argentin
Imperij: poskus utemeljitve mnoštva
No full textThe article exposes two conceptions of politics in postmodernism: following the decline of the classical figure of authority, political thought faces a radical crisis on the level of the possible foundation of political community, although on the other hand, through the promotion of biopolitics, it proclaims the proliferation of the political on the level of life itself. On the basis of the Empire of M. Hardt and A. Negri the author develops three forms of the political subject and argues for the possibility of political emancipation based on the notion of the singular universal.Članek izhaja iz dveh koncepcij politike v postmodernizmu: po eni strani se politična misel po zatonu pojma avtoritete, Drugega, sooča z radikalno krizo glede možnosti utemeljitve politične skupnosti in torej priča o določenem »koncu politike«, po drugi strani pa predvsem skozi promocijo pojma biopolitike, nasprotno, razglaša proliferacijo političnega na ravni samega življenja. V navezavi na delo M. Hardta in A. Negrija Imperij avtorica razvije tri podobe političnega subjekta in poskuša z njihovo pomočjo odgovoriti na vprašanje o možnosti politične emancipacije, ki sloni na pojmu singularnega univerzalnega
Effectiveness of experimental adhesives modified by carbodiimide and solvated by differents solvents
No full textO objetivo deste estudo foi avaliar a influência da incorporação do 1-etil-3- (3-dimetilaminopropil) carbodiimida – EDC (C) no grau de conversão (GC%), na estabilidade da união resina-dentina, na degradação do colágeno e na inativação de MMP de sistemas adesivos experimentais solvatados em acetona (A), etanol (E) ou tetra-hidrofurano (T). O EDC (0,5M) foi adicionado aos primers experimentais constituídos por HEMA, PMGDM e água, solvatados em A, E ou T, formando seis
grupos (A, AC, E, EC, T, TC). O adesivo foi constituído por BISGMA, HEMA, canforoquinona e EDMAB. O GC% foi avaliado por espectroscopia FT-IR e a resistência de união resina-dentina foi avaliada por meio do teste de microtração (RU), imediatamente e após um ano de armazenamento em saliva artificial a 37oC. Os dados foram analisados por meio de análise de variância e o teste de Tukey (α =
0,05) foi aplicado para contraste. Não houve diferença estatística no GC% entre todos os sistemas adesivos (p> 0,05). Os sistemas adesivos contendo EDC mantiveram a estabilidade da RU após armazenagem de um ano (p> 0,05). A incorporação de EDC em primers de sistemas adesivos solvatados principalmente em acetona e etanol parece ser uma estratégia eficaz para melhorar a longevidade das estruturas adesivas ao longo do tempo, uma vez que contribuiu para a estabilidade da adesão resina-dentina.The aim of the present study was to evaluate the influence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide – EDC (C) on the degree of conversion (DC%),
resin-dentin bonding stability, collagen degradation, and MMP inactivation produced
by experimental adhesive systems solvated in acetone (A), ethanol (E) or
tetrahydrofuran (T). EDC (0,5M) was added to experimental primers consisting of
HEMA, PMGDM, and water, solvated in A, E, or T, performing six groups (A, AC, E,
EC, T, TC). The adhesive consisted of BISGMA, HEMA, camphorquinone, and
EDMAB. DC% was evaluated by FT-IR spectroscopy. The μTBS was evaluated
immediately and after one year of artificial saliva storage at 37oC. Data were
analysed using ANOVA and Tukey’s HSD test (α = 0.05). No statistical significance in
DC% was found among all adhesive systems (p > 0.05). The incorporation of EDC
into primers of etch-and rinse adhesives systems solvated mainly in acetone and
ethanol seems to be an effective strategy to improve the longevity of the adhesive
structures over time, as the resin-dentin bonding stability was preserved.34f
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