1,043 research outputs found
Synthesis of Highly Ordered Mesoporous Alumina Thin Films and Their Framework Crystallization to γ-Alumina Phase.
No full textCellulose-to-HMF Conversion Using Crystalline Mesoporous Titania and Zirconia Nanocatalysts in Ionic Liquid Systems.
No full textSynthesis of continuous mesoporous Alumina films with large-sized cage-type mesopores by using diblock copolymers.
No full textThermally stable polymer composites with improved transparency by using colloidal mesoporous silica nanoparticles as inorganic fillers.
No full textEvaporation-induced Coating of Hydrous Ruthenium Oxide on Mesoporous Silica Nanoparticles to Develop High-performance Supercapacitors.
No full text真空紫外１光子イオン化質量分析法を用いた有機ガスのリアルタイム計測技術の開発
Get PDF学位論文 要旨Abstract/要約Outline 以下に掲載：ISIJ International 63(3) pp.534-542 2023. The Iron and Steel Institute of Japan. 共著者：Norihiro TSUJI, Tetsuya SUZUKI,Yasuhiro TOBU,Yuki HATA, Masaaki SUGIYAMA, Masayuki NISHIFUJI, Koji KANEHASH
Supplemental material for The randomized study of endovascular therapy with versus without intravenous tissue plasminogen activator in acute stroke with ICA and M1 occlusion (SKIP study)
No full textSupplemental Material for The randomized study of endovascular therapy with versus without intravenous tissue plasminogen activator in acute stroke with ICA and M1 occlusion (SKIP study) by Kentaro Suzuki, Kazumi Kimura, Masataka Takeuchi, Masafumi Morimoto, Ryuzaburo Kanazawa, Yuki Kamiya, Keigo Shigeta, Norihiro Ishii, Yohei Takayama, Yorio Koguchi, Tomoji Takigawa, Mikito Hayakawa, Takahiro Ota, Seiji Okubo, Hiromichi Naito, Kazunori Akaji, Noriyuki Kato, Masato Inoue, Teruyuki Hirano, Kazunori Miki, Toshihiro Ueda, Yasuyuki Iguchi, Shigeru Fujimoto, Toshiaki Otsuka and Yuji Matsumaru in International Journal of Stroke</p
Mesoporous Carbon Incorporated with In2O3 Nanoparticles as High-Performance Supercapacitors.
No full textRegulation of Cerebral Microcirculation. Update.
No full textThe present symposium during Brain 99 was convened to explore the current aspects of the neural (extrinsic and intrinsic) and chemical control of the microvasculature in the brain with specific relevance to stimuli and rapid flow responses. N. Suzuki demonstrated the presence of neurokinin-1 receptors along the axons of vasoactive intestinal polypeptide-containing cerebrovascular parasympathetic nerves. Since the receptors were activated by substance P, calcitonin gene-related peptide and neurokinin released from coexisting sensory nerve fibers, the parasympathetic (vasodilating) fibers could effect rapid local flow increases. N. Suzuki, however, considered this as part of an elaborate defensive network protecting the brain from invasions by noxious substances. E. Hamel discussed the responses of the microvessels to neurotransmitters and suggested that nitric oxide (NO) released from intrinsic neurons may serve as a relay in the flow activation responses by intracerebral cholinergic fibers originating in the basal forebrain nuclei. D. Busija summarized a vasodilating system of activated N-methyl-D-asparate receptors located on neurons involving Ca influx-NO production, and activated ATP-sensitive potassium channels located in the vascular system. According to Busija, such interactions were disrupted during hypoxia and ischemia due to cyclooxygenase-derived superoxide anion. M. Lauritzen observed a 10 times larger increase in blood flow on stimulation of the climbing nerve as compared with that following the parallel nerve stimulation. The former transmitters are considered by him to be NO and K, and the latter NO and adenosine. Each speaker singled out NO as a common mediator for the microvasculature in the rapid local flow increases.</p
Nicotine directly affects milk production in lactating mammary epithelial cells concurrently with inactivation of STAT5 and glucocorticoid receptor in vitro
Get PDFNicotine from tobacco smoke is absorbed into the bloodstream and transferred into breast milk in breastfeeding mothers. Smoking causes a decrease in breast milk volume, adverse changes to the milk composition, and a shortened lactation period. Breast milk is produced by mammary epithelial cells (MECs) in mammary glands during lactation. However, it remains unclear whether nicotine directly affects milk production in lactating MECs. To address this issue, we prepared a culture model with high milk production ability and less-permeable tight junctions (TJs) by seeding mouse MECs on a cell culture insert. Lactating MECs showed expression of α2, α3, β2, and β4 of nicotinic acetylcholine receptors. The high concentration of nicotine at 10-100 μM inhibited β-casein secretion and caused abnormal localization of TJ proteins. We subsequently investigated whether nicotine at a physiological concentration could affect lactating MECs. Nicotine at 1.0 μM directly inhibited α- and β-casein secretion in lactating MECs concurrently with inactivation of STAT5 and glucocorticoid receptor without affecting the TJ barrier. Nicotine treatment also induced MEC apoptosis concurrently with inactivation of Akt. These results support the adverse effects of nicotine on breastfeeding in smoking mothers
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