406 research outputs found
Effect of laser temporal intensity skew on enhancing pair production in laser - electron-beam collisions
Get PDFRecent high-intensity laser experiments (Cole et al 2018 Phys. Rev. X 8 011020; Poder et al 2018 Phys. Rev. X 8 031004) have shown evidence of strong radiation reaction in the quantum regime. Experimental evidence of quantum effects on radiation reaction and electron-positron pair cascades has, however, proven challenging to obtain and crucially depends on maximising the quantum parameter of the electron (defined as the ratio of the electric field it feels in its rest frame to the Schwinger field). The quantum parameter can be suppressed as the electrons lose energy by radiation reaction as they traverse the initial rise in the laser intensity. As a result the shape of the intensity temporal envelope becomes important in enhancing quantum radiation reaction effects and pair cascades. Here we show that a realistic laser pulse with a faster rise time on the leading edge, achieved by skewing the temporal envelope, results in curtailing of pair yields as the peak power is reduced. We find a reduction in pair yields by orders of magnitude in contrast to only small reductions reported previously in large-scale particle-in-cell code simulations (Hojbota et al 2018 Plasma Phys. Control. Fusion 60 064004). Maximum pairs per electron are found in colliding 1.5 GeV electrons with a laser wakefield produced envelope 7.90 × 10-2 followed by a short 50 fs Gaussian envelope, 1.90 × 10-2, while it is reduced to 8.90 × 10-5, a factor of 100, for an asymmetric envelope
Erratum to "The perception of emotion and social cues in faces" [Neuropsychologia 45 (2007) 1] (DOI:10.1016/j.neuropsychologia.2006.11.001)
No full text[Correction Notice: An erratum for this article was reported in Vol 45(10) of Neuropsychologia (see record 2007-06958-027). The publisher regrets that in the above referenced Guest Editorial, published in special issue 45/1: The perception of emotion and social cues in faces, one of the author names was represented incorrectly. The correct representation is M.I. Gobbini.
The role of subjective social status in living well for carers of people with dementia: findings from the IDEAL programme
No full text‘Improving the experience of Dementia and Enhancing Active Life: living well with dementia. The IDEAL study’ was funded jointly by the Economic and Social Research Council (ESRC) and the National Institute for Health Research (NIHR) through grant ES/L001853/2. Investigators: L. Clare, I.R. Jones, C. Victor, J.V. Hindle, R.W. Jones, M. Knapp, M. Kopelman, R. Litherland, A. Martyr, F. Matthews, R.G. Morris, S.M. Nelis, J. Pickett, C. Quinn, J. Rusted, J. Thom. ESRC is part of UK Research and Innovation (UKRI). ‘Improving the experience of Dementia and Enhancing Active Life: a longitudinal perspective on living well with dementia. The IDEAL-2 study’ is funded by Alzheimer’s Society, grant number 348, AS-PR2-16-001. Investigators: L. Clare, I.R. Jones, C. Victor, C. Ballard, A. Hillman, J.V. Hindle, J. Hughes, R.W. Jones, M. Knapp, R. Litherland, A. Martyr, F. Matthews, R.G. Morris, S.M. Nelis, C. Quinn, J. Rusted. The views expressed are those of the author(s) and not necessarily those of the ESRC, UKRI, NIHR, the Department of Health and Social Care, the National Health Service, or Alzheimer’s Society. The support of ESRC, NIHR and Alzheimer’s Society is gratefully acknowledged
2006 Author Recognition Bibliography
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Unexplained macrocytosis
No full textOBJECTIVES: Macrocytosis is a relatively common finding in adult patients undergoing blood cell counting. Approximately 10percent of patients will have unexplained macrocytosis after laboratory evaluation. Data on the approach to patients with unexplained macrocytosis are limited. METHODS: To investigate this topic and help delineate an approach to this condition, the records of 9779 patients diagnosed in our institution between 1995 and 2005 as having macrocytosis were reviewed. Patients with evidence of liver disease, alcohol abuse, hypothyroidism, folate or vitamin B12 deficiency, hemolysis, or use of any drugs known to cause macrocytosis were excluded. RESULTS: Forty-three patients were found to have unexplained macrocytosis. The median follow-up was 4 years. A total of 11.6percent patients developed a primary bone marrow disorder (two B-cell lymphomas, two with myelodysplastic syndrome, one plasma cell disorder), 16.3percent developed worsening cytopenias, 69.7percent had stable disease, and 2.3percent resolved. The median time to first cytopenia was 18 months, and the mean time to diagnosis of bone marrow disorder was 31.6 months. The outcomes were not significantly different when comparing patients with or without anemia upon diagnosis. The probability of a bone marrow biopsy to establish a diagnosis of a primary disorder was 33.3percent in patients with macrocytosis without anemia compared with 75percent in patients with macrocytosis with anemia. CONCLUSIONS: Patients with unexplained macrocytosis still require close follow-up. We suggest a strategy of follow-up with blood cell counting every 6 months. Bone marrow biopsy should be performed when cytopenias are present because this approach may provide a higher yield of diagnosis and aid with therapeutic decisions.Copyright © 2013 The Southern Medical Association.ANTTILA P, 1995, BRIT J HAEMATOL, V90, P797, DOI 10.1111-j.1365-2141.1995.tb05198.x; BREEDVELD FC, 1981, ACTA MED SCAND, V209, P319; COLONOTERO G, 1992, MED CLIN N AM, V76, P581; DAVIDSON RJL, 1978, J CLIN PATHOL, V31, P493, DOI 10.1136-jcp.31.5.493; DONOFRIO G, 1995, BLOOD, V85, P818; HATTERSL.PG, 1971, AM J CLIN PATHOL, V55, P442; Hoffbrand V, 1997, BRIT MED J, V314, P430; Horstman AL, 2005, EUR J HAEMATOL, V75, P146, DOI 10.1111-j.1600-0609.2005.00441.x; Khalife MA, 2010, BLOOD, V116, P1925; LINDENBAUM J, 1983, BLOOD, V61, P624; Ma X, 2007, CANCER, V109, P1536, DOI 10.1002-cncr.22570; Mahmoud MY, 1996, AGE AGEING, V25, P310, DOI 10.1093-ageing-25.4.310; National Cancer Institute, SEER CANC STAT REV 1; WYMER A, 1990, J GEN INTERN MED, V5, P192, DOI 10.1007-BF02600531; YOUNG M, 1975, J CLIN PATHOL, V28, P12, DOI 10.1136-jcp.28.1.1211
LASER INDUCED EMISSION FROM NFC1 RADICALS ISOLATED IN LOW TEMPERATURE ARGON MATRICES
No full text1. J.V. Gilbert, A. M. Zarubaiko, and S. Lantz. Chem. Phys. Lett. 220, 19 (1994).Author Institution: University of Denver, Denver, Colorado 80208The spectrum and lifetime of laser induced emission from NFCl radicals isolated in low temperature argon matrices is reported. The spectrum is compared to emission observed following the photolysis of gas phase , and the tentative assignment of the gas phase emission to NFCl is The lifetime of the NFCl emission in the matrix is ns. A mechanism involving the ability of different vibrational modes of predissociated electronic states to couple in the low temperature matrix environment is discussed, and used to explain the difference in lifetimes observed for the gas phase and the matrix emission
Polymer microparticle arrays from electrodynamically focused microdroplet streams
Get PDFWe describe instrumentation for forming two-dimensional arrays of polymer microparticles produced from electrodynamically focused microdroplet streams. A single-stage linear quadrupole was used to focus droplets/particles onto silanated glass slides mounted on a computer-driven two-dimensional translation stage. Center-to-center position stability was on the order of 1 mu m. Applications to molecular sorting with polymer particles as host carriers are discussed. (C) 2000 American Institute of Physics. [S0034-6748(00)01506-9].The following article appeared in Review of Scientific Instruments Vol. 71, No. 6, June 2000 and may be found at dx.doi.org/10.1063/1.1150642. This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.https://doi.org/10.1063/1.115064
Unmet care needs of patients with advanced cancer and their relatives: multicentre observational study
No full textObjectives: The care needs of patients with advanced cancer and their relatives change throughout the disease trajectory. This study focused on the care-related problems and needs of patients with advanced cancer and their relatives. This was done from the perspective of centres for information and support. Methods: This cross-sectional study used data from the eQuiPe study: an observational cohort study in which 40 Dutch hospitals participated. All adult patients with a diagnosis of a metastasised tumour and their relatives were eligible. Measures included information on the patients' and relatives' care problems and needs, assessed by the short version of the Problems and Needs in Palliative Care questionnaire. Socioeconomic demographics were also collected. Results: 1103 patients with advanced cancer and 831 relatives were included. Both patients (M=60.3, SD=29.0) and relatives (M=59.2, SD=26.6) experienced most problems in the domain of â € psychological issues'. Both patients (M=14.0, SD=24.2) and relatives (M=17.7, SD=25.7) most frequently reported unmet needs within this domain. The most often reported unmet need by patients was â € worrying about the future of my loved ones' (22.0%); for relatives this was â € fear for physical suffering of the patient' (32.8%). There was no clear relationship between socioeconomic demographics and the experienced unmet needs. Conclusions: The most often mentioned unmet needs consisted of fears and worries, followed by a broad range of topics within multiple domains. Centres for information and support may play a role in reducing the unmet needs of (potential) visitors as these centres provide support on a broad range of topics.Methodologie en Organisatie van Desig
Infrared Spectrum of NFCl Radicals in Low Temperature Argon Matrices
No full text. Gilbert, J.V., Hofsetz, B.D., to be published, J. Phys. Chem., 1992.Author Institution: Department of Chemistry, University of DenverLow temperature argon matrices were prepared by passing in argon through a heated stainless steel metering valve and depositing the effluent on a KCl window maintained at 10K. Peaks at 920 and which could not be assigned to , or to other known species (eg., NF, NCl, , , CLF, ), appeared in the FTIR spectrum of the matrix. In previous radicals had been produced in this manner from , and the assumption was made in these studies that the 920 and peaks were from NFCl. Normal mode calculations, carried out in a reiterative fashion, support this assignment
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