2,946 research outputs found
Neukonzeption der Verschränkung von Theorie und Praxis in der Eingangsphase der Lehramtsstudiengänge
No full textDer Beitrag beschreibt ein Konzept, das an der Pädagogischen Hochschule (PH) Weingarten die Theorie- und Praxis-Verzahnung in der Lehrer/innen-Bildung verbessern soll. Durch die theorieangebundene Ausgestaltung des Orientierungs- und Einführungspraktikums (OEP) und die frühe systematische Verankerung Forschenden Lernens werden die Studierenden bei der Aneignung grundlegender beruflicher Kompetenzen und einer forschend-reflexiven Haltung maßgeblich unterstützt. Dabei stehen bildungswissenschaftliche Reflexionen und Peer-Assessment im Mittelpunkt des Forschenden Lernens und der ersten Berufserfahrung. Gerahmt wird dies von einer Blended Learning-Umgebung, die kooperatives und individuelles Lernen unterstützt.
23.01.2013 | Markus Janssen, Katja Kansteiner, Stefanie Schnebel, Christoph Stamann, Jörg Stratmann & Thomas Wiedenhorn (Weingarten
Computational characterization of dimerization and ligand binding in biological systems
No full textThe self-association of proteins to form dimers or higher-order oligomers is a very common phenomenon in biology. Protein dimerization or oligomerization acts as a control tool for the execution of functions in many biological systems. Three systems were studied by computational methods in this thesis. Cyclic diguanylic acid (CDG) is a ubiquitous messenger involved in bacterial signaling networks. CDG can form an intercalated dimer and bind at the inhibition site of PleD. MD simulations were carried out for the CDG dimer as well as the analogue of CDG (endo-S-CDG) in solution and binding to the PleD protein. It was demonstrated, that dimeric CDG is only marginally stabilized even in high concentration. The results help the fundamental understanding of c-di-GMP and preventing biofilm formation. Insulin is a small protein that plays an eminent role in controlling glucose uptake in cells. Insulin can associate as a dimer which leads to diabetes. The key role of the B24 residue for insulin dimerization was identified. Our work provided an insight for designing analogues of human insulin and thus a therapy for diabetes
Evidence based leadership
No full textAuthor Markus PodduikinMasterarbeit Johannes Kepler Universität Linz 2024Arbeit gesperr
Improving the search for monitoring tools using recommender technology
No full textAuthor Markus Eisl BSc.Masterarbeit Universität Linz 2023Arbeit gesperr
Improving the search for monitoring tools using recommender technology
No full textAuthor Markus Eisl BSc.Masterarbeit Universität Linz 2023Arbeit gesperr
metal-organic framework 4H, 4H-octafluoroazobenezene perfluoroazobenzene
No full textauthor: Markus RödlKumulative Masterarbeit aus einem ArtikelMasterarbeit University of Innsbruck 2022Arbeit gesperr
metal-organic framework 4H, 4H-octafluoroazobenezene perfluoroazobenzene
No full textauthor: Markus RödlKumulative Masterarbeit aus einem ArtikelMasterarbeit University of Innsbruck 2022Arbeit gesperr
Strategi Pelayanan Lintas Budaya Berdasarkan Markus 4:1-34
No full textHarming & Katarina, Cross-cultural Service Strategy based on Mark 4: 1-34. The author conducted a study of the text of Mark 4: 1-34 using qualitative research literature study using the biblical hermeneutic principle. Based on the analysis of the text of Mark 4: 1-34 the authors find there are four cross-cultural service strategies namely by understanding local culture, using media. Harming & Katarina, Strategi Pelayanan Lintas budaya Berdasarkan Markus 4:1-34. Penulis melakukan penelitian terhadap teks Markus 4:1-34 dengan menggunakan penelitian kualitatif studi pustaka dengan menggunakan prinsip hermeneutik Alkitab. Berdasarkan analisis terhadap teks Markus 4:1-34 penulis menemukan ada empat strategi pelayanan lintas budaya yaitu dengan memahami budaya lokal, menggunakan media yang ada dalam budaya, memberdayakan potensi yang ada, dan menciptakan terobosan
Atomistic simulations of transition metal catalyzed reactions using specialized force fields and quantum mechanical methods
No full textIn this thesis, we utilized current computational methods for exploring molecular architectures and dynamical properties of metal-catalyzed reactions. The importance of transition metals (TM) in catalysis was our motivation to work on the development of new empirical force fields and their applications.
TM specialized force fields provide the possibility to characterize complex geometries and relate them to their reactivity. Therefore, we parametrized the VALBOND TRANS force field by refining non-bonded parameters for a large test set of octahedral iridium(III) compounds. The optimized force field allowed a successful ranking of lowest-energy diastereomers and the performance of subsequent molecular dynamic (MD) simulations. Inspired by the natural process of the photosynthesis, Ir-catalysts are also relevant for the light-induced artifical oxidation of water leading to the synthesis of dioxygen. Using parameterized force fields, we studied the role of half-sandwich iridium complexes in different proposed reaction mechanisms. The applied force fields could help to understand catalytic cycles and to establish a basis to guide experimental screenings of new effective catalysts. TM complexes are also key components in harvesting solar energy which encouraged us to investigate the function of relevant compounds such as ruthenium-tris-(2,2'-bipyridine). Its electronic excitation led to a non-equilibrium system in which excess energy was redistributed to the surrounding solvent. The determined energy transfer to the solvent and the vibrational signatures of the surrounding water supplied an explanation for experimental findings
Development of a Software Tool for Analyzing Experimental Data of a Recycling Machine
No full textAuthor DI Markus Kirchmayr, BScMasterarbeit Universität Linz 2022Arbeit nach Ablauf der Sperre auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
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