105,163 research outputs found
Agent-Based Query Optimization in a Grid Environment
No full textThe next generation experiments in High Energy Physics are the driving force for setting up an International Data Grid at CERN, the European Organization for Nuclear Research. Hundreds of Petabytes of data will be distributed and replicated all over the globe starting from 2005. In order to analyse this massive set of distributed data efficiently, we propose a hierarchical query optimisation architecture based on multi-agent technology. The architecture is optimised for the High Energy Physics community but is representative also for other data intensive scientific applications that use distributed data stores and mass storage system
Replica consistency in a Data Grid
No full textA Data Grid is a wide area computing infrastructure that employs Grid technologies to provide storage capacity and processing power to applications that handle very large quantities of data. Data Grids rely on data replication to achieve better performance and reliability by storing copies of data sets on different Grid nodes. When a data set can be modified by applications, the problem of maintaining consistency among existing copies arises. The consistency problem also concerns metadata, i.e., additional information about application data sets such as indices, directories, or catalogues. This kind of metadata is used both by the applications and by the Grid middleware to manage the data. For instance, the Replica Management Service (the Grid middleware component that controls data replication) uses catalogues to find the replicas of each data set. Such catalogues can also be replicated and their consistency is crucial to the correct operation of the Grid. Therefore, metadata consistency generally poses stricter requirements than data consistency. In this paper we report on the development of a Replica Consistency Service based on the middleware mainly developed by the European Data Grid Project. The paper summarises the main issues in the replica consistency problem, and lays out a high-level architectural design for a Replica Consistency Service. Finally, results from simulations of different consistency models are presented
Selective recognition of the activated form of transcription factor NF-kB by a monoclonal antibody
No full textKaltschmidt B, Henkel T, Stockinger H, Baeuerle PA, Kaltschmidt C. Selective recognition of the activated form of transcription factor NF-kB by a monoclonal antibody. Biol Chem Hoppe Seyler. 1995;376:9-16
Dörfer und Deputierte: Rezension auf HSK erschienen
No full textEine Besprechung von Andreas Fahrmeir (Goethe-Universität Frankfurt am Main, Historisches Seminar) zur Dissertation „Dörfer und Deputierte“ von Thomas Stockinger ist seit kurzem auf der geschichtswissenschaftlichen Plattform H-Soz-u-Kult abrufbar: „Auf den ersten Blick überrascht dieses Buch. Es handelt auf fast 1000 Seiten von wenigen Tagen, nämlich den Wahlterminen im Frühjahr 1848 in Frankreich und Cisleithanien. Und nicht nur der Zeitraum, sondern auch der geographische Fokus ist eng begr..
Consistency of replicated datasets in Grid computing
No full textData replication is a well-known technique used in distributed systems in order to improve fault tolerance and make data access faster. Several copies of a dataset are created and placed at different nodes, so that users can access the replica closest to them, and at the same time the data access load is distributed among the replicas. In today's Grid middleware solutions, data management services allow users to replicate datasets (i.e., flat files or databases) among storage elements within a Grid, but replicas are often considered read-only because of the absence of mechanisms able to propagate updates and enforce replica consistency. In this entry we analyze the replica consistency problem and provide hints
for the development of a Replica Consistency Service, highlighting the main issues and pros and cons of several approaches
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The CD system of leukocyte surface molecules: Monoclonal antibodies to human cell surface antigens
No full textCopyright © 2008 John Wiley & Sons, Inc.Many of the leukocyte cell surface molecules are known by "CD" numbers. In this Appendix, a short introduction describes the history and the use of CD nomenclature and provides a few key references to enable access to the wider literature. This is followed by a table that lists all human molecules with approved CD names, tabulating alternative names, key structural features, cellular expression, major known functions, and usefulness of the molecules or antibodies against them in research or clinical applications.Alice Beare, Hannes Stockinger, Heddy Zola and Ian Nicholso
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
The construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
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