1,296 research outputs found
Effects of Moritella viscosa antigens on pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) cell line (SHK-1)
No full textMoritella viscosa is the causative agent of winter ulcer disease in salmonids reared in North-Atlantic countries. In this study the effects of selected M. viscosa antigens on cytotoxicity and pro-inflammatory gene expression in an Atlantic salmon (Salmo salar Linnaeus) macrophage-like cell line (SHK-1) were examined. SHK-1 cells were stimulated with live and heat-killed bacterial cells, extracellular products (ECP) and an extracellular vibriolysin, termed MvP1. Following incubation, cytotoxicity and expression levels of interleukin-1β (IL-1β) and interleukin-8 (IL-8) were examined at different time points. Both live M. viscosa cells and ECP were cytotoxic, but neither heat-killed cells, nor the MvP1 peptidase caused cell death. Expression levels of both IL-1β and IL-8 increased significantly after stimulation with live cells, but heat-killed cells only caused increased IL-8 expression. ECP did not affect IL-1β expression, but did stimulate IL-8 expression. The isolated MvP1 peptidase stimulated both IL-1β and IL-8 expression at the highest concentration tested. This study reveals a difference in the induction of pro-inflammatory gene expression in salmon SHK-1 cells between live and heat-killed M. viscosa cells, and also that an unknown secreted factor is the main stimulant of IL-β and IL-8 expression.ID: S1050464809000990; M3: Article; Accession Number: S1050464809000990; Author: Bryndis Bjornsdottir (a, b); Author: Mark D. Fast (b, 1); Author: Sandra A. Sperker (b); Author: Laura L. Brown (b, 2); Author: Bjarnheidur K. Gudmundsdottir (a, ∗); Affiliation: Institute for Experimental Pathology, University of Iceland, Keldur v/Vesturlandsveg, 112 Reykjavík, Iceland; Affiliation: National Research Council Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, Nova Scotia B3H 2Z1, Canada; Keyword: Moritella viscosa; Keyword: Extracellular products; Keyword: MvP1 vibriolysin; Keyword: Atlantic salmon; Keyword: SHK-1; Keyword: Gene expression; Keyword: Immune response; Keyword: Pro-inflammatory cytokine; Keyword: Interleukin-1β (IL-1β); Keyword: Interleukin-8 (IL-8); Number of Pages: 6; Language: English;Source type: Electronic(1
Thyroid hormone inhibition of IGF-1-mediated glucose uptake in L-6 myoblasts through intercation with alphaVbeta3 integrin
No full textThe Endocrine Society's 90th Annual MeetingFilename: 851334 Contact Author: Sandra Incerpi Dr. Department/Institution: Biology, University Roma TreAddress: Viale G. Marconi, 446City/State/Zip/Country: Rome, 00146, ItalyPhone: ++39-06-57336335 Fax: ++39-06-57336321 E-mail: [email protected]
Epilampra cinerascens Brunner
No full textEpilampra cinerascens Brunner von Wattenwyl, 1865 Synonymy: Epilampra adjuncta Walker, 1868. NHM, London (H). Epilampra subconspersa Walker, 1868. NHM, London (L). Geographical records. Province of Misiones: San Ignacio; prov. of Tucumán: Cañete. Type. NMW, Vienne (T)? as indicated by the author in the original publication. References. Hebard, 1921: 281; Crespo & Valverde, 2008: 174.Published as part of Iglesias, Monica Sandra, 2010, Catalogue of Blattaria (Insecta) from Argentina, pp. 1-33 in Zootaxa 2726 on page 16, DOI: 10.5281/zenodo.20001
Course grades and standardized tests as predictors of successful completion of the associate degree nursing program at Lakeshore Technical College
Get PDFPlan BDue to the increasingly severe shortage of registered nurses, Lakeshore Technical College (LTC) is now more aware of, and more determined to deal with the issues of student recruitment and retention. Successful completion of the Associate Degree Nursing Program (A.D.N.) at Lakeshore Technical College depends on many factors, both intrinsic and extrinsic to the program. Variables that affect the learner such as family concerns, health, or program related issues might lead to problems in school related areas such as retention. Student records of 174 LTC associate degree nursing students, enrolling in the program in and after January of 1997, who graduated, failed, or withdrew from the program by May 2000, will be analyzed. Grades received in specific required general education courses, pre-nursing required science courses, and scores received on the American College Test (ACT) or Assessment of Student Skills for Entry Test (ASSET) will be studied. This data will be examined to determine if a pattern exists between grades, standardized testing scores, and retention in the LTC associate degree-nursing (A.D.N.) program. Analysis of the data obtained in this research may identify factors that could alert faculty members to academic problems and potential failure of the student. It would also allow for early intervention to aid the student through the use of guidance, faculty or peer assistance, and promote successful completion of the program
Author correction: obesity and ethnicity alter gene expression in skin
No full textDaniel Butler was omitted from the author list in the original version of this Article. The Author contributions section now reads: “J.M.W. designed, conducted, and contributed to the writing of the manuscript, prepared Fig. 1. S.G. evaluated and did statistical analysis on the skin and fat samples, prepared Figs. 2–9. J.O.A. evaluated and contributed to writing the manuscript. D.B prepared and sequenced DNA libraries for the skin microbiota data, and wrote the applicable parts of the methods section. C.M. analyzed and wrote up the skin microbiota data, prepared Fig. 10. All authors have read the manuscript and approved its contents. D.D. analyzed and wrote up the skin microbiota data. S.Z. ran and analyzed the skin metabolite data. J.S. assisted in design, analysis and wrote up the skin metabolite data. J.K. assisted in analysis write up of skin and fat data. J.L.B. assisted in analysis, interpretation and writing of the manuscript. P.R.H. designed, analyzed, interpreted the data, and was the primary author of the manuscript.” This has been corrected in the PDF and HTML versions of the Article, and in the accompanying Supplementary Information file.</p
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Crises, Inquiries and the Politics of Blame /
No full text"This study probes deeply into the dynamics of the blame games that seem now to have become an inevitable part of advanced societies' responses to negative events. Resodihardjo's forensic analysis of how such negative events get framed, investigated and accounted for significantly advances our understanding of how incidents and crises affect the reputations and political capital of public authorities, and how they can foster but also significantly impede institutional learning." -Paul 't Hart, Utrecht University, The Netherlands "The crisis is often not even over before the mud starts flying. This little gem of a book outlines causes and consequences of blame games. The author offers strategies for dealing with these blame games. An emerging scholar writing a valuable primer on surviving blame games - warmly recommended!" -Arjen Boin, Leiden University, The Netherlands "This is an important book. Crises are followed by questions and the accountability phase inevitably involves the blame game. In using in-depth case study analysis of tragic incidents at festivals, Sandra Resodihardjo explores why and how blame games start, evolve and are then influenced by a variety of factors. This is a fascinating read, when things go badly wrong the cycle of blame is often complex, involving multiple actors and organisations often battling to frame the event to their own agenda. This should be essential reading not just for scholars studying this critical area of public policy, but practitioners who would undoubtedly learn a lot from the analytical oversight and forensic detail contained in this excellent book." -Mark Bennister, University of Lincoln, United Kingdom This book furthers our understanding of blame games following a crisis event by combining theory and practice in order to answer questions such as: Who is blamed and why? How much blame is this person receiving and why? How can this person respond? And why do these responses not always work? Sandra L. Resodihardjo is Assistant Professor in Public Administration at the Institute for Management Research, Radboud University, The Netherlands.
Communication as comfort: Multiple voices in palliative care
No full textThis exceptional work explores the complexities of communication at one of the most critical stages of the life experience--during advanced, serious illness and at the end of life. Challenging the predominantly biomedical model that informs much communication between seriously ill and/or dying patients and their physicians, caregivers, and families, Sandra L. Ragan, Elaine M. Wittenberg-Lyles, Joy Goldsmith, and Sandra Sanchez-Reilly pose palliative care--medical care designed to comfort rather than to cure patients--as an antidote to the experience of most Americans at the most vulnerable juncture of their lives. With an author team comprised of three health communication scholars and one physician certified in geriatrics and palliative medicine, this volume integrates the medical literature on palliative care with that of health communication researchers who advocate a biopsychosocial approach to health care. Applying communication theories and insights to illuminate problems and to explain their complexities, the authors advocate a patient-centered approach to care that recognizes and seeks to lessen patients\u27 suffering and the many types of pain they may experience (physical, psychological, social, and spiritual) during life-threatening illness
Book Review: Siblings of Children with Autism: A Guide for Families (2nd Edition)
No full textAuthor: Sandra L. Harris & Beth A. Glasberg
Publisher: Woodbine House, 2003
Paper, ISBN: 1-890627-29-1, 180 pp.
Cost: $16.95 USD
Reviewer: Rhonda S. Blac
Twenty-First Century Middle Schooling in New York: Teachers Share Experiences and Perspectives on Remote Teaching and Learning Early in the Global Pandemic
Get PDFIn early 2020, the Covid-19 virus hit many places, including New York City, with such a force that nobody could have foreseen the events following its spread. The education system was pushed to transition itself to meet with 21st century technology. This study explores this disruption in the education system and how middle school teachers in several New York counties responded. What are middle school teachers’ perspectives and practices during the rapid switch to remote teaching? Professor and graduate students in a Curriculum, Instruction, and Assessment class on middle level schooling designed the interview protocol focused on five related areas of the remote learning endeavor: 1) Preparation, 2) Teaching, Learning, and Participation, 3) Social and Emotional effects on Students, 4) Monitoring and Assessment, 5) Looking forward. The findings demonstrate a primarily reactive response and limited preparation. Teachers express a mixed review of successes and struggles with online teaching and the challenges of engagement, participation, and meeting the social emotional needs of restless students who sometimes do not have the parent support or the technological devices that could further assist their success with online learning. Each teacher had their own unique experiences and challenges teaching students through a computer screen
The face of empire: the cultural production of U.S. imperialism in the Panama Canal Zone and California, 1904–1916
Get PDF"The U.S. government's construction of the Panama Canal (1904–1914) presented a template for expansive imperialism in Latin America in the twentieth century. After the highly publicized atrocities of the Philippine–American War (1899–1902) and the popular anti-imperialist movement at the turn of the century, imperial boosters required a new strategy. The U.S. government’s Isthmian Canal Commission (ICC) thus sold the Panama Canal project to the American public as a peaceful, beneficent development project rather than a coercive occupation. Imperial boosters continuously reinforced this message from the construction era onward through the cultural production of attractive, reassuring images that profoundly influenced media coverage of the canal project and the resulting public perceptions of U.S. imperialism in the American-run Panama Canal Zone (PCZ). Visually appealing images of canal construction highlighted the technological wonders of its engineering and made the canal a metaphor for the proclaimed superiority of American civilization in the jungle. The PCZ emerged as an unprecedented model for imperial occupation, in that boosters packaged the annexed territory as an Edenic civilian enclave rather than a militarized zone. The cultural production of this publicity, particularly visual images of technology and white settler life in the PCZ, worked to neutralize popular resistance to U.S. imperial expansion in the early twentieth century.
The publicity triumph of the PCZ was consolidated by corollary mainland initiatives, the two world’s fairs in California in 1915–1916 commemorating the opening of the Panama Canal. Panama, San Diego, and San Francisco became three points on a circuit of imperial power, bound together inextricably with the opening of the canal. San Diego organized the Panama-California Exposition (PCE) in 1915–1916, and San Francisco staged the Panama-Pacific International Exposition (PPIE) in 1915. These two expositions significantly advanced the publicity efforts of empire boosters, while furthering the imperial aspirations of the two cities. San Diego used its fair to exert control over the U.S. Southwest in an effort to forge an inland empire that would position the city as an imperial hub. The PCE employed scientific racism to justify white supremacy, Indian removal, and imperial expansion, both ""at home"" in the U.S. West and ""abroad"" in the PCZ, as imperial boundaries between ""the domestic"" and ""the foreign"" blurred. Fair exhibits and publications celebrated hydraulic engineering in both California and Panama as critical to expanding white American settler societies, and justified the dislocation of indigenous peoples in both locations in the name of progress, modernity, and civilization.
San Francisco’s imperial boosterism also served local needs, as the city used the PPIE to stage a renaissance from the cataclysmic 1906 earthquake and fire and position itself as an imperial metropole on a global stage, a vital outpost on the Pacific Rim. San Francisco boosters strove to turn the fair into a wider celebration of imperialism in the tradition of Western Civilization. The PPIE claimed the legacy of Imperial Rome and the Greek Empire of city-states, which San Francisco aspired to imitate. The PPIE created a spectacle for millions of fairgoers who were dazzled and spellbound by the architecture, landscaping, sculpture, color design, and the unprecedented lighting shows. Fairgoers were lulled into a state of political quiescence by the fair’s sublime beauty and thus consented to imperialism without critically analyzing it. Visiting the fair became an aesthetic experience, one that fostered acquiescence and discouraged dissent. From Panama in 1904 to California in 1916, promoters made the expanding U.S. empire appear peaceful, consensual, beneficent, and beautiful, a marketing strategy that was difficult to argue with."Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2018-05-01The student, Sandra Henderson, accepted the attached license on 2016-04-03 at 19:39.The student, Sandra Henderson, submitted this Dissertation for approval on 2016-04-03 at 20:32.This Dissertation was approved for publication on 2016-04-11 at 07:44.DSpace SAF Submission Ingestion Package generated from Vireo submission #9141 on 2016-07-07 at 14:16:25Made available in DSpace on 2016-07-07T21:14:33Z (GMT). No. of bitstreams: 3
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