167 research outputs found
The Courier, Volume 34, Issue 15, February 23, 2001
No full textStories:
Affirmative Action Plan Faculty Says Plan Good, But Not Enough
2nd Time Around Jennifer Killham Takes Second Shot At Student Trustee Job
Two New Degrees Offered This Fall
More Officers And Prevention Programs For Public Safety
Administrative Computer System 17 Years Old: $5 Million To Replace
Defending Taxpayers Dangerous Meddling–Election Of Two Trustees Could Tip Balance Between Activist, Traditional Factions
Election Finds Home (Page) On The Web
Election 2001: Choosing A New Board Of Trustees–The Students’ Agenda
Ayodele Means Joy
Author Reports Underground RR Ran Through Wheaton
Napster Versus The Record Industry
Chaps Take 7th N4C Title (women’s basketball)
People:
Jennifer Killham
Denis Wright
Tomas Krieglstein
Glennette Tilly Turner
Brian Mueller
Tony Correale
Midwest Ramblers
Tom Kinsell
Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway
No full textProstaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high concentration in seminal plasma
Cognitive Function Variability and Health-related Quality of Life in Multiple Sclerosis: A Comprehensive Analysis Across Different Multiple Sclerosis Types
No full textObjective: To investigate cognitive function variability and health-related quality of life in patients with diverse types of multiple sclerosis (MS).
Materials and Methods: This study involved 780 participants diagnosed with various types of MS. Data was collected using the MS quality of life 54 questionnaire, administered online during the coronavirus disease-2019 pandemic.
Results: The cognitive function scores of the various MS types were found to be significantly distinct, with the relapsing-remitting (RR) type exhibiting the greatest variability. Repeated measures analysis of variance revealed a modest improvement in cognitive function over time in RRMS
patients. Age and health-related quality of life exhibited a highly significant negative correlation (r=-0.63, p<0.001). Heritability analysis suggested that approximately 45% of cognitive function variability is attributable to genetic factors. Specifically, RRMS patients exhibited higher cognitive function scores compared to patients with primary-progressive type and secondary-progressive type of MS (p<0.01 and p<0.05, respectively).
Conclusion: Cognitive function and health-related quality of life differ significantly among the different MS types. Age and genetic factors play critical roles in cognitive health. The findings underscore the need for conducting routine cognitive assessments in MS patients, especially for
those with RRMS, to provide early intervention and enhance patient outcomes. Comprehensive mean square care necessitates the integration of cognitive and physical health management strategies.
Keywords: Multiple sclerosis, cognitive dysfunction, quality of life, rehabilitation, mental healt
Atmospheres of brown dwarfs
No full textChH highlights financial support of the European Community under the FP7 by an ERC starting grant. SLC acknowledges financial support of University of LeicesterBrown Dwarfs are the coolest class of stellar objects known to date. Our present perception is that Brown Dwarfs follow the principles of star formation, and that Brown Dwarfs share many characteristics with planets. Being the darkest and lowest mass stars known makes Brown Dwarfs also the coolest stars known. This has profound implication for their spectral fingerprints. Brown Dwarfs cover a range of effective temperatures which cause brown dwarfs atmospheres to be a sequence that gradually changes from a M-dwarf-like spectrum into a planet-like spectrum. This further implies that below an effective temperature of ≲ 2800K, clouds form already in atmospheres of objects marking the boundary between M-Dwarfs and brown dwarfs. Recent developments have sparked the interest in plasma processes in such very cool atmospheres: sporadic and quiescent radio emission has been observed in combination with decaying Xray-activity indicators across the fully convective boundary.Peer reviewe
Spontaneous music : the first generation British free improvisers
No full textThe British free improvisation scene originated in London and Sheffield during the
mid 1960s. In groups such as AMM, the Spontaneous Music Ensemble and Joseph
Holbrooke, a distinctive and ambitious musicality developed that still occupies most
of its protagonists forty years later.
Marked stylistic contrasts developed within the genre, notably the `atomistic' and
`laminar' methods of interaction. Nonetheless, a consistency of principle and practice
was also apparent that defined British free improvisation as unique. In some respects
the genre resembled its German, Dutch and American counterparts, and also the jazz
and classical avant-gardes that had inspired them. Both conceptually and practically,
however, clear differences remained.
The British free improvisers refined a method and an aesthetic of musical creativity,
which suggested an intimate perspective and a detailed analysis of that which we
accept as `music'. Its techniques and results were unconventional, but remained
consistent with music's defining concepts and experiences. As such, British free
improvisation suggested a more inclusive model of musicality than is common, and
implied a broad critique of the cultural values that define `music' at all. Though the
free improvisers themselves did not explicitly state the connection, their work may be
viewed in the context of Deconstruction: the post-structuralist analytical strategy
associated with philosopher Jacques Derrida.
British free improvisation culminated from innovations within the twentieth century
avant-garde. Referencing styles such as atonality and free jazz, it challenged the
aesthetic, technical and hierarchical standards of Western tradition in a form that was
striking and extreme, but also of logical development and focus. Free improvisation
owed explicit debt to a variety of other musics; its most singular achievement
however, was the redefinition of `rhythm' by which it disguised this fact.
The music of the first generation British free improvisers is reliant upon precise
conceptual and practical execution. But though this has enabled the genre to be
musically innovative, in the long term it has also become a logical problem. With
British free improvisation as its subject, the scrutiny of Deconstruction reveals
significant discrepancies between what `free improvisation' implies and what it
actually represents
A meta‐review of the impact of compression therapy on venous leg ulcer healing
No full textThis meta-review aimed to appraise and synthesise findings from existing systematic reviews that measured the impact of compression therapy on venous leg ulcers healing. We searched five databases to identify potential papers; three authors extracted data, and a fourth author adjudicated the findings. The AMSTAR-2 tool was used for quality appraisal and the certainty of the evidence was appraised using GRADEpro. Data analysis was undertaken using RevMan. We identified 12 systematic reviews published between 1997 and 2021. AMSTAR-2 assessment identified three as high quality, five as moderate quality, and four as low quality. Seven comparisons were reported, with a meta-analysis undertaken for five of these comparisons: compression vs no compression (risk ratio [RR]: 1.55; 95% confidence interval [CI] 1.34-1.78; P <.00001; moderate-certainty evidence); elastic compression vs inelastic compression (RR: 1.02; 95% CI: 0.96-1.08; P <.61 moderate-certainty evidence); four layer vs <four-layer bandage systems (RR: 1.07; 95% CI: 0.82-1.40; P <.63; moderate-certainty evidence); comparison between different four-layer bandage systems (RR: 1.08; 95% CI: 0.93-1.25; P =.34; moderate-certainty evidence); compression bandage vs compression stocking (RR 0.95; 95% CI 0.87-1.03; P =.18; moderate-certainty evidence). The main conclusion from this review is that there is a statistically significant difference in healing rates when compression is used compared with no compression, with moderate-certainty evidence. Otherwise, there is no statistically different difference in healing rates using elastic compression vs inelastic compression, four layer vs <four-layer bandage systems, different four-layer bandage systems, or compression bandages vs compression stockings.Full Tex
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
No full textElevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci. Experimental downregulation of gene expression in Drosophila melanogaster and Danio rerio identified 20 genes at 11 loci that are relevant for heart rate regulation and highlight a role for genes involved in signal transmission, embryonic cardiac development and the pathophysiology of dilated cardiomyopathy, congenital heart failure and/or sudden cardiac death. In addition, genetic susceptibility to increased heart rate is associated with altered cardiac conduction and reduced risk of sick sinus syndrome, and both heart rate-increasing and heart rate-decreasing variants associate with risk of atrial fibrillation. Our findings provide fresh insights into the mechanisms regulating heart rate and identify new therapeutic targets
ESLO1: entretien 091
No full textExtrait du corpus d'Orléans, réalisé dans le cadre de l'Enquête SocioLinguistique à Orléans à la fin des années 1960.01 depuis 20 ans02 travail du mari ; cadre pour élever enfants03 plus ou moins ; préfère Paris ou le Midi04 non ; Orléans ville renferméeT1 journée : promenade, cinéma ; difficulté d'alller au théâtreT2 dimanches à la campagne ; manque de distractions à OrléansT5 pour ; sauf s'il y a des enfantsL2 sortie au restaurant, promenade à la campagneT7 un fils instituteur ; un fils dans la marineE1 contente du régime actuelE8 davantage de liberté ; nouvelles méthodes (et leurs inconvénients)E9 pourrait être bienE2 contreE3 langues modernes ; exemples familiauxE4 suivant les capacitésE5 16 ans trop ; plutôt 14 ansE6 pareil ; suivant la profession visée ; toutes les professions ne conviennent pas aux femmesE9 RR pratique religieuse ; Orléans farouchement catholique ; fête de Jeanne d'Arc ; équivalences catholiques etIdentifiant du témoin : KO 376 Femme, 50 ans (née en 1919 à St Denis), sans profession. Enregistré par Bernard Vernieret Catherine Sée-Gross, le 11 avril 1969 au domicile du témoin. Questionnaires enregistrés : questionnaire sociolinguistique questionnaire ouvert (questions 01-04 ; T1-T2 ; T5 ; T7 ; L2 ; E1-E6 ; E8-E9 ; P4 ; P9-P10 ; omelette). Classe politique du témoin : pas posée (?). Acoustique : assez claire, bruits de rue
Women and independence in the nineteenth century novel : a study of Austen, Trollope and James
No full text'Women
and
independence in the nineteenth century novel : a
study
of
Austen, Trollope
and
James', begins
with the
concept of
independence
and works through the three
most common usages of
the
word.
The first, financial independence (not
needing to
earn one's
livelihood)
appears to be
a necessary prerequisite
for the
second
and third forms
of
independence,
although it is by
no means an
unequivocal good
in
any of
the
novels.
The
second,
intellectual
independence (not
depending
on others
for
one's opinion or conduct;
unwilling
to be
under obligation
to
others),
is
a matter of asserting independence
while employing
terms
which society recognizes.
The third,
of
being independent, is
exemplified
by
an
inward
struggle
for
a
knowledge
of self.
In
order
to trace the development
of
the idea
of self
during the
nineteenth century,
I have
chosen a group of novels which seem
to be
representative of
the beginning, the
middle, and the
end of
the period.
Particular
attention
is
given
to the
characterizations of
Emma
Woodhouse, Glencora Palliser, Isabel Archer, Milly Theale and
Maggie
Verver. Whereas in Jane Austen's
novels
the self
has a
definite shape
which the heroine
must
discover, and
in Anthony Trollope's
novels
the
self
(reflecting
the idea
of socially-determined man) must
learn to
accommodate social and political changes,
in Henry James's
novels
the
self
determined by
external manifestations
(hollow
man)
is
posed
against
the exercise of
the free
spirit or soul.
Jane Austen's
novels
look backward,
as she reacts against
late
eighteenth century romanticism, and
forward,
with
the development
of
the heroine
who exemplifies
intellectual independence. Anthony
Trollope's
women characters are creatures of social and political
adaptation; although
they do
not
derive their
reason
for being
from
men,
they
must accommodate
themselves to
men's wishes.
And
Henry James looks backward,
wistfully, at
Austen's
solid, comforting,
innocent
self and
forward, despairingly, to the dark,
unknowable self
of
the twentieth
century
A.W.N. Pugin's English residential architecture in its context
No full textThis Dissertation investigates all of A.W.N. Pugin’s known English residential
architecture for the first time, placing it in the context of the domestic and institutional
architecture of comparable small buildings, particularly Anglican parsonages, of the
period in which he lived and worked.
The Dissertation is preceded by a summary of the theoretical issues that architects
were addressing from the beginning of the nineteenth century, in particular those
which Pugin was later to make a central part of his own theoretical writings.
Following an examination of the conventions of the domestic architecture of the
period, the Dissertation analyses Pugin’s own buildings, primarily categorising them
by plan type. Pugin’s attitude to the orientation, location and landscape of his work is
then considered, followed by an analysis of his preferred building forms, their
materials, their detailing, and their decoration. In addition, the Dissertation
investigates the extent to which Pugin’s architecture was actually historicist, reviving
English or Continental Gothic forms and details.
The Dissertation further investigates Pugin’s professional practice as a domestic
architect, defining the nature of his partnership with his favoured building contractor,
George Myers, in the context of contemporary contracting practice. The practical
problems of Pugin’s constructions, and the character of his professional relationship
with his clients are also assessed.
The thesis proposes that elements of Pugin’s architectural theory existed previous to
his career amongst English architectural writers and critics, but that medium and
small houses designed between 1800 and the mid-1840s were overwhelmingly based
on a limited number of conventionalised plans. It will show that Pugin’s residential
planning was inherently different from that of these conventional buildings, and that it
is classifiable into a number of distinct categories. This thesis furthermore argues that
Pugin’s residential architecture was often far from functional and was not essentially
historicist.
This thesis will show that the planning of medium and small houses changed radically
from the 1840s, incorporating aspects of planning which Pugin had pioneered; a
conclusion suggests to what extent Pugin’s architectural creativity was expressive of
cultural change and preoccupation beyond the realm of architecture.
An Appendix is attached which summarises the chronology of all of Pugin’s known
residential works
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