206 research outputs found
Vrioco(r)nium and Deva
No full textThe author restores the ancient name of Wroxeter, given as Viroconium in most sources, with the form Vrioconium [Cornovium]. The first element wrio-is an Indo-european name for “ stronghold”, attested in Thracian (Bria), Messapic (Uria), Tokharian (A ri, B, riye) ; any connection with Mycenian ri-jo-seems problematic.L’auteur restitue le nom antique de Wroxeter, le plus souvent Viroconium dans les sources, sous la forme Vrioconium [Cornovium]. Il dégage dans * wrio-un nom indo-européen de la forteresse, attesté en thrace (Bria), messapien (Uria), tokharien (A ri, B, riye), mais un rapport avec mycénien ri-jo-paraît problématique.Hamp Eric P. Vrioco(r)nium and Deva. In: Etudes Celtiques, vol. 36, 2008. pp. 69-74
Meningkatkan Motivasi Belajar PAHBP Materi Ajaran Avatara dan Deva Melalui Model Pembelajaran Project Based Learning di Kelas VII SMP Negeri 2 Arut Selatan Kabupaten Kotawaringin Barat Semester 1 Tahun Pelajaran 2019/2020: Improving the Motivation of PAHBP Teaching Materials Avatar and Deva Through the Project Based Learning Model in Class VII SMP Negeri 2 Arut Selatan Regency Kotawingin Barat Semester 1 for the 2019/2020 Academic Year
No full textThe low learning motivation of students is very influential on the acquisition of student achievement, especially in the matter of Avatara and deva teachings. This is evidenced by the acquisition of pre-test results for Avatara and deva teachings from 6 seventh-grade students of SMP Negeri 2 Arut Selatan. Seeing the statement above, the author is interested in researching and testing the extent to which the motivation to learn PAHBP in avatara and deva material is through a project-based learning model. This research method uses classroom action research. The research was carried out at SMP Negeri 2 Arut Selatan Class VII. The research was carried out from August 2019 to October 2019. The research subjects were Class VII students of SMP Negeri 2 Arut Selatan. Data collection techniques in this research are observation, interview, and documentation techniques. The results of the evaluation of the second cycle are known that classical learning completeness reaches (100%) with the average final score of students reaching (84.8) which previously in the pre-cycle classical learning mastery was known to reach (33.33%) with an average final test score students reached (65.95) and in the first cycle of classical learning completeness reached (75%) with an average final test score of students (74.2). From this information, it can be said that the project-based learning model can be applied to the Avatara and deva teaching materials and can increase learning motivation in Class VII semester I SMP Negeri 2 Arut Selatan
Interrelationships between heath utility measurements, disease activity and psychological factors in Behçet's disease
No full textObjective: To measure the health utilities Time Trade-Off (TTO) and Standard Gamble (SG), that ask to consider sacrifices in terms of length of life (TTO) or risk of death (SG) for improvements in quality of life in Behcet's disease (BD), and explore the interrelationships with disease activity, depression, anxiety and fatigue. Method: TTO, SG, EQ-5D-5L, EQ VAS, depression (PHQ-9), anxiety (GAD-7) and fatigue (MAF) questionnaires were administered to 103 adult BD patients. Disease activity was assessed using the Behçet's Disease Activity Index (BDAI). Results: Mean TTO was 0.72 ± SD 0.27 and mean SG 0.70 ± SD 0.34. Moderate/severe depression was identified in 55.2%, moderate/severe anxiety in 35.1% and moderate/high fatigue in 97.7% patients. TTO negatively correlated with depression (p < 0.01), anxiety (p < 0.01) and fatigue (p < 0.01) but did not correlate with BDAI. Cluster analysis revealed one cluster where psychological factors rather than disease activity may have influenced TTO and SG scores. Conclusions: TTO and SG show that BD patients would on average forgo 28% of their remaining life or run a 30% risk of death to avoid the condition. Complex interrelationships with depression, anxiety and fatigue may be more influential than disease activity in treatment decision making.</p
Multivariate Money: A statistical analysis of Roman Republican coin hoards with special reference to material from Romania
No full textThe aim of this thesis is assess the usefulness of the statistical analysis of coin hoards for the
examination of aspects of ancient societies including coin use and exchange. Special attention was
paid to various aspects of ‘formation processes.’ The thesis was divided into three parts.
Part I — Background. This Part initially reviews the history of the project and then goes
on to examine the concept of money in the light of anthropological and economic work. A brief
discussion of types of exchange (gift, barter, commodity exchange) in societies is offered. The Part
is concluded with a review of previous statistical analyses of coin assemblages.
Part II—Analysing Hoards A large database of Roman Republican coin hoards was collected
for this project. The problems with this type of data, its storage and retrieval are discussed. The
database is then analysed in great detail in order to answer a series of numismatic, archaeological
and statistical questions.
Correspondence analysis was used on twenty-two subsets of the data to reveal patterning in
the data-set which is discussed. A new variant of cluster analysis was developed to subdivide
the data set whilst minimising the time series element. The results are compared to principal coordinates
and detrended correspondence analyses. The analyses reveal aspects of the use and supply
of Roman coinage over Europe and show clearly the unique nature of the Romanian data.
An attempt is made to estimate the speed of circulation of coin in Italy. It is shown that the
nature of coin supply leads to variation between periods which is the result of simple probability
and sampling theory, not changes in the speed of circulation of coin as has been suggested by other
authors.
Simulation studies are used to examine the validity of estimates of coin production and annual
coin loss.
The results are summarised. The usefulness of the techniques used is discussed. In the light of
the formation processes examined, the patterns in coin hoard data are tentatively interpreted.
Part III — Romania. It is argued that to attempt a detailed interpretation of the patterns
revealed above the material must be seen in its archaeological context. This case study is offered as
one such attempt. Romania was chosen for two reasons: 1) the exceptional quantity of hoards found
in an area outside Roman control; 2) the unique evidence for the copying of coins. After reviewing
various aspects of Romanian archaeology, a detailed analysis of the problem of copies is offered
including the results of a large scale archaeometallurgical study conducted under the direction of
the author. Estimates of the quantities of coins copied are given. A brief review of the settlement
evidence in the counties of Sibiu, Alba and Hunedoara, of special settlement and structure types,
and of hoards of silverware is presented. The thesis concludes by discussing the nature of Dacian
society and its use of coin in the light of the theoretical discussions in Part I, the evidence for coin
supply discussed in Part II and the results of the analyses in Part III in the context of the wider
archaeological evidence
Communication with patients of South Asian origin:problems and solutions in the context of rheumatoid arthritis
No full textRheumatoid arthritis is a common chronic disease associated with significant morbidity and mortality. As with all chronic conditions, active participation by the patient, in areas ranging from accepting the diagnosis and its treatment to the implementation of coping strategies, is essential for effective management. Involving any patients in these process can be difficult; however patients of South Asian origin can present particular challenges. Many patients of South Asian origin have beliefs about disease causation and the utility of pharmacological and non‐pharmacological treatments that differ from those held by other patients. Communication difficulties can make it difficult for health care professionals to address these issues. We discuss strategies to support patients and encourage their involvement including linguistically appropriate educational material, peer support and telephone helplines
PENERAPAN 3D FLUID ATTENUATION INVERSION RECOVERY ISOTROPIC SEBAGAI ALTERNATIF PENINGKATAN KUALITAS CITRA, INFORMASI ANATOMI DAN EFISIENSI WAKTU PEMERIKSAAN MRI BRAIN
No full textPENERAPAN 3D FLUID ATTENUATION INVERSION RECOVERY ISOTROPIK SEBAGAI ALTERNATIF PENINGKATAN KUALITAS CITRA, INFORMASI ANATOMI DAN EFISIENSI WAKTU PEMERIKSAAN MRI BRAIN Luh Deva Wedayanti1, Lina Choridah2, Darmini31Program Pascasarjana Imaging Diagnostik Magister Terapan Kesehatan, Poltekkes Kemenkes Semarang, Indonesia2Fakultas Kedokteran Universitas Gaja Mada Yogyakarta, Indonesia3Jurusan Teknik Radiodiagnostik dan Radioterapi Poltekkes Kemenkes Semarang, IndonesiaCoresponden author : [email protected] Isotropic Turbo spin echo Acquisition (VISTA) merupakan suatu teknik pada sekuen Fast Spin Echo (FSE)/Turbo Spin Echo (TSE) dengan modifikasi khusus yang dioptimalkan untuk pencitraan Isotropic 3D. Istilah isotropic berarti bahwa voxel yang dihasilkan oleh akuisisi tiga dimensi (3D) mengukur hal yang sama disetiap arah. Sehingga kemungkinan gambar dapat dilakukan format ulang dengan resolusi yang sama kesegala arah. 3D isotropic adalah salah satu dari data 3D volumetric imaging yang memiliki besaran size pixel sama x, y dan z sehingga memiliki keuntungan kualitas gambar yang sama pada saat merubah view dari axial ke sagital dan dari sagital ke coronal karena dari manapun dilihat akan memiliki size pixel yang sama. Data 3D isotropic memberikan evaluasi data yang berpotensi mengevaluasikan bagian tubuh terkecil, karena mengingat bahwa scan 2D tidak dapat secara optimal mengevaluasi beberapa struktur kompleks dikepala.Tujuan Penelitian ini yaitu untuk menganalisis pengaruh penerapan 3D FLAIR isotropic sebagai alternatif peningkatan kualitas citra, informasi anatomi dan efisiensi waktu pemeriksaan pada pemeriksaan MRI brain sekuen 2D FLAIR konvensional.Kesimpulan yang didapatkan dalam penelitian ini yaitu terdapat perbedaan kualitas citra antara sekuen 2D FLAIR konvensional dan 3D FLAIR isotropic pada pemeriksaan brain. Didapatkan perbedaan SNR (Signal to noise Rasio) yang bermakna secara statistik dengan P-Value 0,000 antara sekuen 2D FLAIR konvensional dan 3D FLAIR isotropic pada sampel MRI brain keseluruhan, karena nilai SNR sekuen 2D FLAIR konvensional dan 3D FLAIR isotropic
The Behçet's centres of excellence: A new paradigm for care delivery in complex diseases
No full textGenetics of Behçet's disease
No full textPURPOSE OF REVIEW: This article discusses recent genetic and epigenetic associations involved in the pathogenesis of Behçet's disease.RECENT FINDINGS: Genetic studies have supported the strong association of human leukocyte antigen-B and Behçet's disease, and high production of tumour necrosis factor and low production of interleukin (IL)-10, which have led to therapy based on controlling these effects. Polymorphisms that affect the response to pathogens (TLR and FUT2) are leading to increased interest in responses to microbiomes. Inflammation in Behçet's disease results in vascular damage and several single nucleotide polymorphisms in chemokine and adhesion molecules may be involved in this process. Increased levels of inflammatory cytokines including IL-1β and IL-17 have been linked to altered expression of microRNAs, miR155, miR21 and miR23b. DNA methylation changes in monocytes and lymphocytes have been described that affect the function of these cells.SUMMARY: Genetic and epigenetic changes affecting cells and molecules involved in Behçet's disease offer new pathways for research, including cytoskeletal protein function, that will provide new targets for therapy, and potentially address the ethnic differences seen in validation of gene studies.</p
Design and Melting Behavior of the MSFR Freeze Plug
No full textThe freeze plug is a key safety component of the molten salt fast reactor (MSFR), one of six next-generation nuclear reactor technologies being developed under the Generation IV International Forum (GIF). It should be designed to melt if an accident occurs, allowing the MSFR to drain before it incurs structural damage.Two freeze plug concepts have been considered in recent years, in which the plug is melted either through the decay heat produced in the core, or through heat generated by special heating rings and stored in steel blocks adjacent to the freeze plug. Variations consisting of both a single freeze plug, and multiple smaller plugs contained in a metal plate, have been proposed. This work seeks to evaluate the feasibility of these designs and study how parameters such as the sub-cooling of the plug affect melting times. Additionally, an alternative, wedge-shaped freeze plug design is proposed for increased reliability. Simulations performed in COMSOL showed that the decay heat plug melts within 600 s only if placed within 0.01 m of the mixed core flow. Because such a placement makes the plug vulnerable to temperature and velocity fluctuations in the core during regular operation of the reactor, this design is considered unfeasible and is not recommended for further study. On the other hand, melting times under 600 s were possible with the heating ring design for a range of sub-cooling amounts and plug configurations, suggesting that thisdesign is promising. A thin frozen layer was shown to form on top of the metal grate in the multi-plug configurations, preventing heat transfer through the top of the plate. Although the melting behavior of this layer warrants further investigation, its insulating effect was found to generally cause the single-plug designs to melt faster than the multi-plug designs.A simplified, isothermal model of the wedge-shaped plug was simulated using the enthalpy-porosity approach to account for convection. To model the sinking of the wedge, an extended Darcy term approach was developed based on an analytical solution which was validated experimentally, with good agreement. This model shows that melting of the wedge is unsteady, and that melting times depend linearly on the wedge angle and sub-cooling. Unfortunately, melting times of the wedge plug could not be estimated with realistic, non-isothermal, time-dependent boundary conditions. For future study, a customizable numerical solver such as OpenFOAM is recommended, which would allow the sinking of the solid phase to be modeled more robustly through an immersed boundary method
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