68 research outputs found

    Estudo da viabilidade de inserção da empresa Tonello Artefatos de Couro no comércio internacional

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    O mercado internacional se mostra uma alternativa vantajosa para expansão comercial para pequenas empresas. A Tonello Artefatos de Couro atua no mercado interno há 20 anos, evidenciando interesse para incorporar-se ao comércio internacional por meio de exportações dos artigos de couro. Para tal, utilizam-se conceitos de internacionalização de empresas, processos iniciais de exportações e estratégias de marketing. Averiguou-se com a pesquisa de mercado que o Uruguai é o país ideal para o início dos trabalhos de exportação. Esta pesquisa constituiu-se em uma investigação qualitativa de nível exploratório, utilizando métodos de estudo de caso e pesquisa-ação, a fim de aprimorar os setores da empresa e prepará-la para o comércio internacional. Para entender os processos da internacionalização realizou-se entrevistas, contatos com o proprietário da companhia e demais profissionais das áreas envolvidas. Identificou-se através dos dados coletados e de pequenos investimentos realizados que é viável internacionalizar a empresa. [resumo fornecido pelo autor]The international market is an advantageous alternative for small business expansion. The company Tonello Artefatos de Couro has been operating in the domestic market for 20 years, and there is an opportunity to join international trade through exports of leather items. For this purpose, the concepts of company internationalization, initial export processes and marketing strategies are used. It was found through a market research that Uruguay is the ideal country to start exporting. This research consisted of a qualitative exploratory investigation, using case study and action research methods, in order to improve the company's sectors and prepare it for international trade. In order to understand the internationalization processes, the company's manager and other professionals in the areas involved were identified and contacted. It was identified through the data collected and small investments made that it is feasible to internationalize the company. [resumo fornecido pelo autor

    Jugular veins in transient global amnesia: innocent bystanders.

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    Background and Purpose—Transient global amnesia (TGA) has been associated with an increased prevalence of internal jugular valve insufficiency and many patients report Valsalva-associated maneuvers before TGA onset. These findings have led to the assumption of hemodynamic alterations in intracranial veins inducing focal hippocampal ischemia. We investigated this hypothesis in patients with TGA and control subjects. Methods—Seventy-five patients with TGA and 75 age- and sex-matched healthy subjects were enrolled into a cross-sectional study. Extracranial and transcranial high-resolution venous echo-color-Doppler sonography was performed blindly in all patients and control subjects. Blood flow direction and velocities were recorded at the internal jugular veins, basal veins of Rosenthal, and vein of Galen, both at rest and during Valsalva-associated maneuvers. Results—Mean age of patients with TGA was 60.38.0 years (median, 60 years; range, 44–78 years); 44 (59%) were female (female/male ratio: 1.42). Internal jugular valve insufficiency (left, right, or bilateral) was found to be more frequent in patients with TGA than in control subjects: 53 (70.7%) versus 22 (29.3%; P0.05). Blood flow velocities in the deep cerebral veins of patients with TGA did not differ from control subjects both at rest and during Valsalva-associated maneuvers. Intracranial venous reflux was neither observed in patients with TGA nor in control subjects despite unilateral or bilateral internal jugular valve insufficiency during prolonged and maximal Valsalvaassociated maneuvers. Conclusions—This study, although confirming the association between TGA and internal jugular valve insufficiency, challenges the hypothesis that cerebral venous congestion plays a significant role in the pathogenesis of TGA

    Educational intervention to improve the safety medication process. a review using the GRADE approach

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    Objectives Medication errors are frequent and affect patient safety in all the world. This review using the GRADE approach aims to identify the educational intervention which improves nursing medication competences and knowledge.Methods According to PRISMA statement, a review was conducted.Key findings In this review of nine studies, we determined that there is a lot of educational intervention aimed to improve nursing knowledge, such as traditional classroom training, simulation, e-learning, slide show presentations and the use of posters and pamphlets or mobile application. All of these can improve the medication process and nursing skills. Only three studies reached moderate, and two studies reached low-quality ratings.Conclusions Our findings show that all educational interventions can lead to medication without harm.This work will inform regulators, public health initiatives and policy makers considering the nursing educational intervention for increasing patient safety and improve medication competence and knowledge

    A worldwide bibliometric analysis of published literature on medication errors

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    Objectives: The aim of the study was to map the recent literature on medication error to monitor the state of research and explore emerging research fronts. Specifically, the co-occurrences analysis aimed to research the conceptual structure of the medication errors, whereas the coauthorship analysis aimed to research the "authorities" that influenced the academic and political discussion on medication errors. Methods: The search for relevant studies was carried out through the Scopus. To map and monitor the state of research on medication error, a preliminary analysis was conducted through the year of publication, type of article, and language. The count of citation shows the most relevant work among those included. Bibliometric analyses were conducted, such as coauthorship analysis and co-occurrences analysis. Results: The search strategy yielded 5393 articles. Of these, 1267 articles were included. Four main themes emerged from this bibliometric analysis: (a) the exploration of human factors related to health care professionals that increase the risk of medication error, (b) the investigation of behaviors and strategies that can prevent the error in the preparation and administration stage, (c) the analysis of the benefits related to the presence of the pharmacist in hospital settings, and (d) the exploration of the consequences of a medication error and/or adverse effects of drugs. Conclusions: For the first time, a bibliometric analysis of medication errors research in the world has been conducted and demonstrated that there is a wealth of contributions already being made that are well aligned to the World Health Organization challenge

    Endothelial dysfunction in carotid elongation

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    A b s t r a c t BACKGROUND AND PURPOSE Internal carotid artery (ICA) elongation (coiling and kinking) has been suggested as a risk factor for carotid dissection. Since vasomotion is known to be impaired in spontaneous cervical vessel dissection, we investigated whether endothelial-dependent vasodilation in subjects with carotid coiling and kinking is compromised. METHODS We undertook a case-control study using high-resolution ultrasound and measured flow mediated dilation (FMD) of the brachial artery in 80 subjects with carotid elongation and in 80 age- and sex-matched healthy controls (HC). The hemodynamic impact of carotid elongation was taken into consideration subdividing mild/moderate kinking from severe kinking according to a peak systolic blood flow velocity >150 cm/s. RESULTS FMD did not differ among subjects with coiling (14.51 ± 7.86%), mild/moderate kinking (14.38 ± 9.58%) and HC (15.53 ± 8.48%), while subjects with a severe kinking had a significantly lower FMD (8.38 ± 3.26). CONCLUSIONS Among subjects with carotid elongation, those with severe kinking have an impaired endothelial-dependent vasodilation and might be prone to carotid dissection

    Early Diagnosis of Type-2 Cardio-renal Syndrome by Doppler Sonographic Evaluation of Renal Vasoconstriction

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    Renal failure of type-2 cardio-renal syndrome is due to renal hypoperfusion secondary to heart failure and is mediated by an imbalance between vasoconstrictors and vasodilators. The decrease in glomerular filtration rate does not correlate with left ventricular ejection fraction. Aim of this study was to evaluate, by Doppler sonography, renal hemodynamic alterations in heart failure. Thirty patients (age: 51±15yr) with dilated cardiomyopathy (DCM) and 20 normal subjects (C) were studied. Cardiomyopathy was essential in 36.6%, post-ischemic in 36.6%, alcoholic in 16.7%, post-myocarditis in 10% of patients. All patients were hemodynamically stable. In each patient, echocardiography and renal Doppler sonography (interlobar arterial pulsatility index, PI-K) were performed the same day, together with BUN, creatinine, NT-proBNP measurement. Patients with DCM had normal kidneys morphology and volume. LVEF was 26±6.8%. PI-K was increased compared to C (1.74±0.71 vs 0.95±0.19, p<0.001) and also renal function was impaired (creatinine 128.5±84 vs 70±30 umol/L, p<0.01, BUN 11.6±5.8 vs 7±1.5 mmol/L, p<0.01). Prevalence of renal failure was 36.6% (NYHA 1-2: 23%, NYHA 3-4: 52.9%) while prevalence of increased PI-K was 83.3% (NYHA 1-2: 69.2%, NYHA 3-4: 94.1%). PI-K was increased already in mild heart failure (NYHA 1-2) (PI-K: 1.37±0.3 p<0,01), but more so in patients with more severe heart dysfunction (NYHA 3 e 4) (PI-K: 2,1±0,8 p<0.01) without significant correlation with LVEF or right atrial pressure. There were no differences in creatinine or BUN among patients with different severity of heart dysfunction (creatinine 105±23 vs 140±104 umol/L, urea 10.3±5.7 vs 12.3±6 mmol/L). NT-proBNP was increased in patients with DCM (6249.61±3.963 ng/L) and did not correlate with LVEF, PI-K, renal function, right atrial pressure. In conclusion, in patients with chronic heart failure renal vasoconstriction can be demonstrated by Doppler-sonography in the early stage, when renal function is still normal, and increases with the worsening of heart failure. Renal Doppler resistance indices may be used for early diagnosis of type-2 cardiorenal syndrome and for prevention of acute, diuretic-induced, renal failure. Author Disclosures: D. Sacerdoti: None. S. Gaiani: None. S. Tonello: None. E. Franceschini: None. P. Pesce: None. P. Bizzotto: None. G. Bombonato: None. C. Sarais: None. M. Bolognesi: None. Key Words: Heart failure • Renal circulation • Renal function • Doppler ultrasoun

    Placebo effect in acupuncture

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    reservedIn questo elaborato si affronta la questione della pratica di agopuntura come medicina per un gran numero di condizioni cliniche. Questa terapia è infatti dibattuta a causa dei potenziali effetti placebo da cui viene influenzata. Diversi studi scientifici hanno cercato di indagare nel corso degli anni questa tecnica, utilizzando gruppi di controllo per evidenziare gli effetti specifici dell’agopuntura. Per questa ragione, in questa tesi di laurea viene proposto un protocollo sperimentale innovativo, progettato per valutare l’efficacia dell’agopuntura come trattamento rilassante. Nel primo capitolo viene innanzitutto descritta la pratica dell’agopuntura e le sue storiche origini. Vengono anche introdotti gli effetti analgesici e terapeutici supportati da alcune evidenze che questa terapia può procurare. Infine, vengono esposti i possibili meccanismi neurobiologici sottostanti alla generazione di questi effetti. Il secondo capitolo approfondisce l’effetto placebo e le sue conseguenze nella pratica di agopuntura. In relazione a questo vengono quindi trattati alcuni metodi a cui si è fatto ricorso per controllare questo effetto nelle condizioni sperimentali. In conclusione, il terzo capitolo si concentra sulla descrizione del nuovo protocollo sperimentale. Esso prevede uno studio condotto in doppio cieco e con tre gruppi di controllo per evidenziare al meglio le differenze nell’induzione del rilassamento tra le varie condizioni di trattamento. Viene perciò descritta la procedura che verrà seguita e la strumentazione che verrà utilizzata per misurare e confrontare i risultati

    The literary canon on television: An analysis of Borges por Piglia on Argentinian TV Pública

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    Distintos autores han ubicado a Jorge Luis Borges como la figura central del canon literario argentino del siglo XX, con una gravitación que se extiende hacia escritores de toda América Latina. El objetivo del presente artículo es analizar uno de los más recientes y relevantes actos de canonización de Borges: el programa Borges por Piglia de la Televisión Pública Argentina, producido en 2013. Se trata de cuatro conferencias transmitidas por televisión, con gran circulación masiva posterior en internet, a cargo del escritor Ricardo Piglia. El presente trabajo propone una indagación de los aspectos discursivos y comunicativos de las conferencias para comprender en qué consiste este gesto de producción de valor sobre la obra de Borges. Se analizará el ethos de Piglia como locutor, la centralidad de la calidad literaria en su argumentación y los esfuerzos de volver a Borges un escritor cercano a un público general. A su vez, será una estrategia analítica clave establecer comparaciones con otras intervenciones realizadas por otros críticos que también indagan la obra de Borges. El trabajo se propone así pensar nuevas reconfiguraciones del canon literario argentino, enmarcadas en una política cultural pública.Several authors have placed Jorge Luis Borges as the most relevant author in Argentinian 20th century literary cannon, whose influence can be traced in many other Latin American writers. This study aims to tackle one of most recent and relevant Borges’ canonization act: the television programme Borges por Piglia by the TV Pública Argentina made in 2013. It consists of four conferences transmitted massively via television and internet websites, held by the writer Ricardo Piglia. This study set out to examine discourse and communication aspects in these conferences in order to understand value production related to Borges’ work. The paper will analyze Piglia’s discursive ethos, the importance of aesthetic value and the critic’s aim to turn Borges into a close figure for the audience. A comparative strategy will be undertaken to explore Piglia’s conference in relation to other critics’ interventions on Borges. Te present results provide solid evidence to discuss contemporary configurations in Argentinian literary cannon, framed in official cultural policies.Fil: Salas Tonello, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales; Argentin

    Análise comparativa de custos na viticultura familiar: um estudo de caso em Bento Gonçalves - RS

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    A agricultura familiar tem um papel fundamental na economia da Serra Gaúcha, especialmente no cultivo da uva, sendo responsável por manter tradições e movimentar a economia local. Diante disso, este trabalho teve como objetivo realizar o diagnóstico organizacional de uma propriedade rural familiar localizada na Linha Buratti, em Bento Gonçalves (RS), a fim de identificar uma oportunidade de melhoria para ela. Para isso, foi realizado um diagnóstico da propriedade com base em áreas da administração, como finanças, marketing, operações, materiais e gestão de pessoas, permitindo compreender os principais desafios enfrentados na rotina produtiva. A proposta de melhoria apresentada consistiu na aplicação prática da análise de custos por variedade, com o intuito de tornar as decisões mais técnicas e estratégicas. Portanto, o objetivo deste trabalho foi realizar análise comparativa de custos na viticultura em uma propriedade rural familiar. O levantamento de dados ocorreu por meio de visitas à propriedade, entrevistas com os gestores e análise de documentos internos, possibilitando a coleta de informações detalhadas sobre o funcionamento da produção. A partir disso, implementou-se o custeio por absorção e foram calculados indicadores financeiros, como margem de contribuição, ponto de equilíbrio e retorno sobre o investimento (ROI), com a finalidade de avaliar o desempenho econômico das variedades cultivadas. Os resultados obtidos demonstraram a relevância da gestão de custos como instrumento de apoio à tomada de decisão, reforçando a importância de um sistema contínuo de acompanhamento econômico para o fortalecimento da sustentabilidade financeira da atividade agrícola familiar. [resumo fornecido pelo autor

    Schede biografiche delle maestranze

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    Biografie degli imprenditori e delle maestranze edili: 1. Domenico Castelli (Fontanino) 2. Tommaso Damino 3. Niccolò Scala 4. Giovanni Battista Caccia 5. Antonio Paleari 6. Bernardo Tonello e Pietro Alberti 7. Giuseppe Bernascone 8. Andrea Bianchi 9. Franciscus de Ordinis 10. Donato Mazzi 11. Antonio Nuvolone 12. Pietro Sassi 13. Stefano Castagna da Lugano 14. Bartolomeo de Giudici 15. Francesco Fedele 16. Giacomo Lambruzzi 17. Rocco Porcaro 18. Domenico Tavolaccio 19. Francesco Massari 20. Matteo Albertini 21. Domenico De Rossi 22. Ercole Boselli 23. Lorenzo Dini 24. Venantio Costantini 25. Giovan Battista Lucatelli 26. Giovanni Pietro Gianni 27. Giulio Cianchi 28. Giovanni Battista Bolla 29. Paolo Cassetti 30. Fabio Cristofari 31. Carlo Piervissani 32. Bernardo Borromini 33. Gio. Antonio Roncaioli 34. Carlo Galli 35. Lazzaro Massari 36. Lorenzo Barbi 37. Antonio Raggi 38. Giovanni Cesare Dona 39. Francesco Antonio Fontana 40. Simone e Giovanni Battista Giorgini 41. Sillano Sillani 42. Vincenzo Corallo 43. Francesco Frontone 44. Pietro Gargiust
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