132,613 research outputs found
"Frank Meining, Harvey Crist, Rufus Shultz (Salem Band)"
No full textThis portrait of three members of the Salem Band captures Frank Meinung, Harvey Crist, and Rufus Shultz
Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction in Diabetic Patients
No full textIntroduction: The cause of erectile dysfunction (ED) in diabetic patients is complex and involves both neurogenic and vasculogenic components and is often hard to treat. Aim: To study the effect of low-intensity extracorporeal shock wave therapy (Li-ESWT) therapy on a subgroup of diabetic patients with ED who are responders (PDE5I-R) and non-responders (PDE5I-NR) to phosphodiesterase 5 inhibitors (PDE5I). Methods: Analysis of pooled data from 5 double-blind, sham-controlled trials was performed. In this sub-analysis, of 350 patients in the PDE5I-R group and with vasculogenic ED, we found 61 patients with diabetes mellitus who underwent LI-ESWT. Another 48 patients (of 53) belonged to the PDE5I-NR group. Baseline efficacy was evaluated with the International Index of Erectile Function–Erectile Function domain questionnaire (IIEF-EF) for the PDE5I-R and with Erection Hardness Score, IIEF-EF, and flow-mediated dilation technique for the PDE5I-NR. Main Outcome Measures: Change in the IIEF-EF score after treatment of diabetes-induced ED with Li-ESWT in the PDE5i-R group vs the PDE5i-NR group. Results: LI-ESWT therapy was found to be effective in both subgroups of diabetic patients. Minimally clinical important difference in IIEF-EF score was achieved in 50%, 79.5%, 77.3%, and 65.9% of the subjects in the active group in after the sixth shockwave (SW) treatment evaluation (just before initiating the seventh SW session) and at 1 month, 6 months, and 12 months after the last SW treatment, respectively. The difference among the groups was significant (P < .05) after the sixth treatment and in all the follow-up periods. In the PDE5I-NR group, 55% of the active group were converted to PDE5I-5-R after LI-ESWT. The difference between the active and sham groups was statistically significant in all the tested measures (P < .001). Conclusion: LI-ESWT is safe and effective for the treatment of ED in PDE5I-R and PDE5I-NR groups. Spivak L, Shultz T, Appel B, et al. Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction in Diabetic Patients. Sex Med Rev 2019;XX:XXX–XXX
Reframing Agribusiness: Moving from Farm to Market Centric
No full textAgribusiness is moving from farm to market centric, where effective activities anticipate and respond to customers, markets, and the systems in which they function. This evolution requires a broader conceptualization and more accurate definition, to convey a more dynamic, systemic, and integrative discipline, which increasingly is committed to value creation and the sustainable orchestration of food, fiber, and renewable resources. We discuss the forces driving this shift to the market, offer a new and more representative definition of agribusiness, provide models to illustrate some of the most compelling trends, and articulate key elements and implications of those models.agribusiness definition, conceptual models, market centric, market systems, Agribusiness, Marketing, Production Economics,
New constituents from Mikania laevigata Shultz Bip. ex Baker
No full textA new phenylpropanoid and two new diterpenes were isolated from the leaves of the plant Mikania laevigata Shultz Bip. ex Baker. The structures of these compounds were established by 1D- and 2D-nuclear magnetic resonance spectroscopic techniques and mass spectrometry data. Taraxerol, lupeol, coumarin, syringaldehyde, trans-melilotoside, cis-melilotoside, adenosine, patuletin 3-O-beta-D-glucopyranoside, kaempferol 3-O-beta-D-glucopyranoside, quercetin 3-O-beta-D-glucopyranoside, methyl 3,5-di-O-caffeoyl quinate, and 3,3`,5-trihydroxy-4`,6,7-trimethoxyflavone were isolated too. In addition, the compounds dihydrocoumarin, spathulenol, caryophyllene oxide, kaurenoic acid, beyerenoic acid, and lupeol acetate were identified by GC-MS. (C) 2010 Elsevier Ltd. All rights reserved.FAPESPCAPESCNP
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
A Social Network Analysis of Global Citizenship Education in Europe and North America
No full textIn the last decade GCED has developed in Europe and North America (EUNA) through conceptual, political and pedagogical negotiations among policymakers, educators, and community members. Working from the geographic area understood as “the global north”, EUNA actors are positioned within complex global relations. Drawing on the results of a Social Network Analysis, this chapter is a contribution towards understanding patterns of relationships among key GCED actors across the region. Adopting a whole network approach, the study discusses the structural characteristics of the system following the investigation of three one-mode networks, based on direct ties: collaboration, information exchange, and meetings
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
“The system is rigged against me:” exploring a white supremacist community on 4Chan and perceptions of white supremacy at the University of Pittsburgh
No full textDigital technologies have provided people with new tools to interact and build community. With the rise of the internet in the 1960s, and the World Wide Web in the 1990s, people with access to the internet have communicated across large distances at faster speeds than ever before. In the present digital era, people form meaningful communities in chat rooms, online games, and through social media. The web has also provided tools for racially-based communities to grow and thrive. This study examines one such online community: the white supremacist message board “Politically Incorrect” on the website 4Chan.org. I conducted Participant Observation in this community to understand how this community defines membership and belonging, and I analyzed one discursive symbol that is important to them: the “redpill.” This symbol represents community members’ belief in white genocide, and the way they cope with the negative emotions that are intertwined with this belief. Through my analysis of the redpill symbol, I explore the complex and emotional nature of ideology, and how it works to build our identities and sense of community, while also empowering us to act. This research exemplifies one way that white people are making sense of their whiteness online, especially whiteness centered around white supremacy.
The online portion of my research is supplemented with interviews conducted at the University of Pittsburgh. I interviewed five students and two administrators to gain a sense of how those in my community are thinking about and dealing with white supremacy in their own lives, as well as how the University handles discrimination. I then compare the ways Left-leaning students and people against white supremacy think about and discuss dealing with white supremacy, with the feelings of social isolation expressed by those on “Politically Incorrect.” Through my analysis, I show that the immediate backlash to white supremacy may be fueling the emotions that lead white people to build community through white supremacy. This study concludes with suggestions for future research inquiries in the name of understanding, and ultimately decreasing, white supremacy, as well as an analysis of my own emotional experiences in conducting this research
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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