5,175 research outputs found
RDLS-SS-DWT v. 0.9
No full textThis fileset contains the implementation of RDLS-DWT and SS-DWT in JPEG 2000 (RDLS-SS-DWT v. 0.9), which was used in a research described in: R. Starosolski, “Application of reversible denoising and lifting steps to DWT in lossless JPEG 2000 for improved bitrates,” Signal Processing: Image Communication, Vol. 39, Part A, pp. 249-63, DOI: 10.1016/j.image.2015.09.013, 2015 and R. Starosolski, “Skipping selected steps of DWT computation in lossless JPEG 2000 for improved bitrates,” submitted. This software is intended for research purposes only; it is provided "as is"; author makes no warranty of any kind, either express or implied, with respect to this software. <br
SS Northland Echo
No full textPhotograph - A view of the steamboat, SS Northland Echo on the Athabasca River. Athabasca, Albert
SS Athabasca River - 02
No full textPhotograph - A view of the SS Athabasca River paddle steamer on the river, Athabasca, Albert
RIC-HSCT for MF/SS
No full textAdvanced-stage mycosis fungoides and Sezary syndrome (MF/SS) have a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT), particularly using a reduced-intensity conditioning (RIC) regimen, is a promising treatment for advanced-stage MF/SS. We performed RIC-HSCT in nine patients with advanced MF/SS. With a median follow-up period of 954days after HSCT, the estimated 3-year overall survival was 85.7% (95% confidence interval, 33.4-97.9%) with no non-relapse mortality. Five patients relapsed after RIC-HSCT; however, in four patients whose relapse was detected only from the skin, persistent complete response was achieved in one patient, and the disease was manageable in other three patients by the tapering of immunosuppressants and donor lymphocyte infusion, suggesting that graft-versus-lymphoma effect and "down-staging" effect from advanced stage to early stage by HSCT improve the prognosis of advanced-stage MF/SS. These results suggest that RIC-HSCT is an effective treatment for advanced MF/SS
SS Northland Sun at Mirror Landing, AB
No full textPhotograph - The paddle-wheeler, SS Northland Sun, docked at shore in Mirror Landing, Albert
SS Northland Light at Sawridge, AB
No full textPhotograph - Paddle-wheeler, SS Northland Light, docked at the shore. Sawridge, A
Bioactive alkaloids from Nepalese Corydalis chaerophylla D.C. acting on the regulation of PCSK9 and LDL-R in vitro
No full textFour new alkaloids Chaeronepaline-A (1), Chaeronepaline-B (2), Chaeronepaline-C (3), and Chaeronepaline-D (4) were isolated from Corydalis chaerophylla D.C. collected from Nepal and their structures were elucidated by spectroscopic data, 1D, 2D NMR and mass spectrometry. The structures were established as 3,12- Dimethoxy-5,6-dihydroisoquinolino [2,1-b] isoquinolin- 7- ium- 2, 9- diol (1), 7-Methyl-2,3 : 11,12-bis(methylenedioxy)-7,13a-secoberbin-13-14-epoxide (2), 7- methyl-5, 6, 7, 8- tetrahydro- 8H-spiro-9,14-dihydroxy-11,12-methylenedioxy-indane-isoquinoline (3) and 7- methyl-5, 6, 7, 8- tetrahydro- 8H-spiro-9,14-dihydroxy-11,12-methylenedioxy-indane-isoquinoline-N-oxide (4). The new alkaloids were tested in human hepatoma cell line to assess their ability to modulate the expression of low-density lipoprotein receptor (LDL-R), of proprotein convertase subtilisin/kexin 9 (PCSK9) and to affect cellular cholesterol biosynthesis with the aim to evaluate their potential hypocholesterolemic effect. Results indicated that compounds 2 and 3 upregulate the LDLR, and inhibited the cholesterol biosynthesis with compound 2, which also reduced the secretion of PCSK9 by Huh7 cells. These in vitro data indicated a potential hypocholesterolemic effect of compound 2 that requires further in vivo validation
VacStockpile; a tool to estimate the potential impacts for stockpiling vaccines for vaccine-preventable diseases of children
No full text"The VacStockpile has been designed to help planners and policy makers evaluate the potential health and cost impacts of stockpile decisions for each type of pediatric vaccine for an array of scenarios regarding possible vaccine shortages. The consequences of a vaccine shortage evaluated include potential doses of vaccine shortage, replenishment costs to replace stockpile doses that are used for shortages or discarded because of expiry of shelf life, and a number of potential health consequences (e.g., number of cases, hospitalizations and deaths) that may occur under various vaccine shortage scenarios. Although VacStockpile has been designed for use in the United States, it can be applied to other situations or locations where vaccine stockpiles are being maintained or considered."[authors, Sundar S. Shrestha, Martin I. Meltzer, Gregory S. Wallace,"Revised on: 03/30/2009."Mode of access: Internet.Suggested citation for manual: Shrestha SS, Meltzer MI, Wallace GS. VacStockpile V1.0: A manual to aid users in estimating the potential impacts of stockpiling vaccines for vaccine-preventable diseases of children (Beta test version). Atlanta: Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services; 2008.2009677
MedCon pre-event
No full text"The MedCon:Pre-Event has been designed to estimate the baseline medical care requirements (i.e., the number of persons that would require medical care) of a displaced population following a disaster due to pre-existing medical conditions. Users of MedCon:PreEvent should note that the MedCon:Pre-Event has not been designed for estimating the medical care requirements due to direct impact of the event (e.g., injuries and illness) or additional medical care requirements resulting from the aggravation of the existing medical condition. The intended users of the MedCon:Pre-Event model are public health preparedness planners at local, state, and federal levels involved in addressing the large scale medical care requirements resulting from man-made and natural disasters."[authors, Sundar S. Shrestha, Martin I. Meltzer, Daniel M. Sosin]."Revision date: 07/06/2009."MedCon:Pre-Event uses the Microsoft Windows operating system (Microsoft Windows 2000 or higher) and Excel (Microsoft Office 2000 or higher). We recommend using a computer with at least a 486 Pentium processor and at least 128MB RAM. MedCon:Pre-Event requires at least 2 megabytes of storage space on the computer's hard drive.Suggested citation for manual: Shrestha SS, Meltzer MI, Sosin DM. MedCon: Pre-Event V1.0 A manual to aid users to estimate pre-event the population at risk of medical consequences in a disaster (Beta test version). Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Atlanta, GA, 2009: 49 pp.20091085
That's 'é' not 'þ' '?' or '☐': a user-driven context-aware approach to erroneous metadata in digital libraries
No full textIn this paper we present a novel system for user-driven integration of name variants when interacting with web-based information systems. The growth and diversity of online information means that many users experience disambiguation and collocation errors in their information searching. We approach these issues via a client-side JavaScript browser extension that can reorganise web content and also integrate remote data sources. The system is illustrated through three worked examples using existing digital libraries
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