1,721,766 research outputs found

    Rupture de la tolérance au soi : de l'immunité innée aux maladies auto-immunes

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    Séminaire FSER organisé par Jean-François Bach (Académie des Sciences), Jules Hoffmann (IBMC, Strasbourg) et Antonio Coutinho (Gulbenkian Science Institute, Oeiras, Portugal) du 26 au 31 juillet 2010 Participants Shizuo Akira, Jean-François Bach, Bruce Beutler, Jeffrey Bluestone, Lucienne Chatenoud, Robert L. Coffman, Max Cooper, Antonio Coutinho, Jonathan Ewbank, Siamon Gordon, Jules A. Hoffmann, Tasuku Honjo, John F. Kearney, Juan Jose Lafaille, Ann Marshak-Rothstein, Fiona Powrie, Jeffrey ..

    Non-self RNA sensing in virus infected cells and activation of antiviral immunity

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    Colloque organisé par Jean-Luc Imler (Université de Strasbourg) et Raul Andino (UCSF, USA) du 27 août au 1er septembre 2012 Participants Shizuo Akira, Raul Andino, Bruce Beutler, Stephen Cusack, Ding Shou-Wei, Takashi Fujita, Akira Tajima-Goto, Otto Haller, Jules Hoffmann, Veit Hornung, Jean-Luc Imler, Karim Majzoub, Carine Meignin, Eric Miska, Jan Rehwinkel, Carla Saleh, Rotem Sorek, Volker Thiel, Joao Trindade Marques, Ronald van Rij, Olivier Voinnet, Friedemann Weber -- Abstract Innate imm..

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Perspective phylogénétique de l’immunité innée / Phylogenetic Perspectives of Innate Immunity

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    Colloque organisé par Jules Hoffmann, Alan Ezekowitz et Fotis Kafatos du 21 au 27 mai 2004 Participants Shizuo Akira, Frederick Ausubel, Bruce Beutler, Jean-Laurent Casanova, Jeffery Dangl, Louis Du Pasquier, Jonathan Ewbank, Alan Ezekowitz, Tomas Ganz, Siamon Gordon, Akira Goto, Charles Hetru, Jules Hoffmann, Fotis C. Kafatos, Michael Karin, Elena Levashina, Cosimo Martinelli, Alexei Matskevitch, Mike Osta, Paola Ricciardi-Castagnoli, Olivier Voinnet, Stefan Wyder, Wayne M. Yokoyama Compte-r..

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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