1,720,975 research outputs found

    Less than 1% cerebrospinal fluid leakage in 1,803 translabyrinthine vestibular schwannoma surgery cases.

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    OBJECTIVE: To determine the incidence rate of cerebrospinal fluid (CSF) leak after translabyrinthine vestibular schwannoma surgery since the alteration of the surgical procedure. To compare with previous series and other series in literature. STUDY DESIGN: Database analysis. SETTING: Tertiary referral neurotologic private practice. PATIENTS: A series of 1,803 patients who underwent translabyrinthine vestibular schwannoma surgery between 1993 and 2009. The result of this group was compared with corresponding series. INTERVENTION: Translabyrinthine and extended translabyrinthine vestibular schwannoma surgery. Literature review and comparison. MAIN OUTCOME MEASURES: Rates of CSF leak in this series and historical perspective of the outcome. RESULTS: Fifteen patients (0.8%) of 1,803 cases had CSF leaks. The method used since 1993 has shown a significant improvement compared with major case series of the last 10 years. CONCLUSION: The methods used in translabyrinthine vestibular schwannoma surgery in our center can reduce CSF leakage to an absolute minimum. Compared with all large series, this could be a new era of translabyrinthine vestibular schwannoma surgery

    Specific Microbial Communities Are Selected in Minimally-Processed Fruit and Vegetables according to the Type of Product

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    Fruits and vegetables (F&V) products are recommended for the daily diet due to their low caloric content, high amount of vitamins, minerals and fiber. Furthermore, these foods are a source of various phytochemical compounds, such as polyphenols, flavonoids and sterols, exerting antioxidant activity. Despite the benefits derived from eating raw F&V, the quality and safety of these products may represent a source of concern, since they can be quickly spoiled and have a very short shelf-life. Moreover, they may be a vehicle of pathogenic microorganisms. This study aims to evaluate the bacterial and fungal populations in F&V products (i.e., iceberg lettuces, arugula, spinaches, fennels, tomatoes and pears) by using culture-dependent microbiological analysis and high-throughput sequencing (HTS), in order to decipher the microbial populations that characterize minimally-processed F&V. Our results show that F&V harbor diverse and product-specific bacterial and fungal communities, with vegetables leaf morphology and type of edible fraction of fruits exerting the highest influence. In addition, we observed that several alterative (e.g., Pseudomonas and Aspergillus) and potentially pathogenic taxa (such as Staphylococcus and Cladosporium) are present, thus emphasizing the need for novel product-specific strategies to control the microbial composition of F&V and extend their shelf-life

    Petrous bone cholesteatoma: classification, management and review of the literature.

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    OBJECTIVE: To discuss the classification of petrous bone cholesteatoma (PBC) and add a subclassification; to review the existing literature and to propose the ideal surgical management of PBC based upon the experience of the largest series published in the literature until now. STUDY DESIGN: Retrospective analysis. SETTING: Quaternary referral neuro-otologic private practice. MATERIALS AND METHODS: The data of 129 patients who underwent surgery for PBC between 1979 and 2008 were analyzed with respect to the classification, type of the approach used, facial nerve lesion and its management, recurrences and outcome. RESULTS: Out of the 129 PBC cases 64 were supralabyrinthine, 9 infralabyrinthine, 7 infralabyrinthine-apical, 48 massive and 1 apical. The facial nerve was involved in 95% of the cases. Hearing could not be preserved in 82% of the cases due to the extent of the lesions and the surgical approaches used. The internal carotid artery, jugular bulb and the lower cranial nerves were infrequently involved, but demanded careful identification and meticulous care to avoid complications. Obliteration of the cavities provided a safe solution for protection of the exposed dura and the vital neurovascular structures. Recurrences were observed in 5 cases. CONCLUSION: The classification of PBC is fundamental to choose the appropriate surgical approach; the facial nerve is involved in almost all the cases, radical removal takes priority over hearing preservation and cavity obliteration is important to protect the vital neurovascular structures which may be exposed

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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