117,413 research outputs found

    Settling in aggregating colloidal suspension : influence of volume fraction and tank inclination

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    Senis D., Allain C., Gorre-Talini L. Settling in aggregating colloidal suspension : influence of volume fraction and tank inclination. In: Transferts dans les systèmes sédimentaires : de l'échelle du pore à celle du bassin. Réunion spécialisée SGF-TRABAS/CNRS, Paris 27-28 septembre 1999. Résumés. Strasbourg : Institut de Géologie – Université Louis-Pasteur, 1999. pp. 131-133. (Sciences Géologiques. Mémoire, 99

    Effect of indacaterol on arterial blood gases in patients suffering from acute exacerbation of COPD

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    SummaryAimThe administration of β2-agonists to patients with airways obstruction often results in transient decrease in PaO2 despite concomitant bronchodilation. This effect is potentially dangerous for patients suffering from acute exacerbation of COPD (AECOPD). In this study, we investigated the effect of indacaterol 150 μg and 300 μg on the arterial blood gas tensions of hospitalised patients with AECOPD.MethodsWe explored the acute effects on arterial blood gases and spirometry of two doses of indacaterol Breezhaler (150 and 300 μg) in 12 patients hospitalised because of an AECOPD in 2 non-consecutive days under open-label, randomized, crossover conditions, with blind evaluation. Blood specimens were taken just before the inhalation and at 15, 30, 60, 120, 240 and 360 min after inhalation of each treatment, and spirometry was performed at the same time points.ResultsBoth doses of indacaterol did not cause significant changes in blood gases, although some patients with relatively well-preserved PaO2 presented transient episodes of oxygen desaturation that normalize spontaneously in a very short time. Moreover, they induced a significant mean increase in FEV1 and FVC, although the improvement caused by indacaterol 300 μg was larger.ConclusionsIndacaterol up to 300 μg is a potent bronchodilator that may induce small, transient decrease in PaO2 mainly in patients with relatively well-preserved PaO2. There appeared to be no clinical consequences of these PaO2 abnormalities in patients suffering from AECOPD

    Vats lung reduction in patients with advanced emphysema

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    We prospectively analyzed the intermediate-term results of thoracoscopic lung reduction performed unilaterally or bilaterally in selected patients with advanced emphysema. Unilateral lung reduction was performed intentionally in patients with asymmetric emphysema (n=21). Overall, among 39 patients operated on unilaterally, 13 subsequently underwent contralateral treatment during the follow-lip. One-stage bilateral lung reduction was intentionally performed in 8 patients with symmetric emphysema. Mortality rate was 2.1% (n=1) and morbidity rate was 36% (n=17). Mean hospital stay was 10.5 days. At 6 months, significant improvement was achieved as regards FEV1, FVC, dyspnea index, and six minute walk test, indipendently by the surgical approach. In particular FEV1 improved of 40% in unilaterally treated patients, whereas in the bilateral group FEV1 improved of 57% and 42% after one-stage or two-stage reduction, respectively. Both unilateral and bilateral thoracoscopic lung reduction can produce significant improvement in dyspnea, lung function and quality of life in properly selected patients

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?

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    In this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Letter from unknown writer to Jesse L. Boyce

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    Letter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
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