201 research outputs found
Azerbaijan and Azerbaijanis in the short story book of Cihan Aktaş titled
No full textDüşünce, inceleme kitaplarıyla olduğu kadar öyküleriyle de tanınan Cihan Aktaş, 1992 – 2009 yılları arasında dokuz öykü kitabı yayımlamıştır. Özellikle Azize’nin Son Günü (1997) adlı öykü kitabında olmak üzere, öykülerinde Azerbaycan’dan ve Azeri Türklerinden bahseden yazar, bu metinlerde gerek Azeri Türklerinden ilginç portreleri edebiyatımıza kazandırmakta, gerekse Azerbaycan kültürüyle, folkloruyla, sosyal ve siyasi hayatıyla, ekonomik şartlarıyla ilgili önemli bilgiler aktarmaktadır. Ayrıca başta Baku olmak üzere Azerbaycan coğrafyasına ve çevre bölgelere ilişkin izlenimlerini öyküleştirmektedir. Bu makalede, Cihan Aktaş’ın Azize’nin Son Günü adlı öykü kitabına yansıyan Azerbaycan ve Azeri Türkü imgesi/algısı incelenmeye çalışılacaktır.Cihan Aktaş who is known by his books of thought and review as well as short stories published nine short story books between 1992 and 2009. The author, who refers to Azerbaijan and Azerbaijanis, especially in his short story book titled the Last Day of Azize (1997), either brought interesting portraits of Azerbaijani Turks in these texts or conveyed important information related to the culture, folklore, social and political life and economical conditions of Azerbaijan. He also narrated his impressions related to Azerbaijan geography and environmental area, especially to Baku. In this article, we will attempt to understand image/perception of Azerbaijan and Azerbaijanis reflecting on the book of Cihan Aktaş titled “the Last Day of Azize”
Cihan Aktaş’ın "Azize’nin Son Günü" adlı öykü kitabında Azerbaycan ve Azeriler
No full textDüşünce, inceleme kitaplarıyla olduğu kadar öyküleriyle de tanınan Cihan Aktaş, 1992 – 2009 yılları arasında dokuz öykü kitabı yayımlamıştır. Özellikle Azize’nin Son Günü (1997) adlı öykü kitabında olmak üzere, öykülerinde Azerbaycan’dan ve Azeri Türklerinden bahseden yazar, bu metinlerde gerek Azeri Türklerinden ilginç portreleri edebiyatımıza kazandırmakta, gerekse Azerbaycan kültürüyle, folkloruyla, sosyal ve siyasi hayatıyla, ekonomik şartlarıyla ilgili önemli bilgiler aktarmaktadır. Ayrıca başta Baku olmak üzere Azerbaycan coğrafyasına ve çevre bölgelere ilişkin izlenimlerini öyküleştirmektedir. Bu makalede, Cihan Aktaş’ın Azize’nin Son Günü adlı öykü kitabına yansıyan Azerbaycan ve Azeri Türkü imgesi/algısı incelenmeye çalışılacaktır.Cihan Aktaş who is known by his books of thought and review as well as short stories published nine short story books between 1992 and 2009. The author, who refers to Azerbaijan and Azerbaijanis, especially in his short story book titled the Last Day of Azize (1997), either brought interesting portraits of Azerbaijani Turks in these texts or conveyed important information related to the culture, folklore, social and political life and economical conditions of Azerbaijan. He also narrated his impressions related to Azerbaijan geography and environmental area, especially to Baku. In this article, we will attempt to understand image/perception of Azerbaijan and Azerbaijanis reflecting on the book of Cihan Aktaş titled “the Last Day of Azize”
The ongoing challenge of ventilator-associated pneumonia: epidemiology, prevention, and risk factors for mortality in a secondary care hospital intensive care unit
No full textSummary: Background: Ventilator-associated pneumonia (VAP) is a leading cause of morbidity and mortality among intensive care unit infections. Despite various preventive measures, the incidence of VAP remains high. Aims: This study aimed to explore the epidemiology and risk factors for VAP associated mortality in a secondary care hospital, comparing outcomes before and after implementing a VAP prevention bundle. Methods: This retrospective study was conducted from July 1, 2021, to June 30, 2023, at a secondary care hospital. Patients over 18 years old who underwent mechanical ventilation for more than 48 hours were included. The study compared the incidence, microbiological etiology, and outcomes of VAP before and after implementing the VAP prevention bundle and analyzed risk factors for mortality from VAP. Results: A total of 83 patients diagnosed with VAP were included. Despite concerted efforts to implement the VAP prevention bundle, there was no significant decrease in the VAP rate per 1000 ventilator days, early-onset VAP, secondary bloodstream infections, acute respiratory distress syndrome, and 30-day mortality. The microbiological etiology of VAP remained consistent between the two periods. A decrease in lymphocyte count and albumin level were identified as independent risk factors for 30-day mortality. Conclusions: Concerted efforts to implement a VAP prevention bundle did not significantly reduce the incidence or improve outcomes of VAP in this secondary care hospital setting. The microbiological etiology remained unchanged. Monitoring lymphocyte count and albumin level may help identify patients at high mortality risk. Further research is needed to develop more effective VAP prevention and management strategies
Clonal relationship in fluconasole resistant candida parapsilosis strains isolated from blood cultures
No full textNozokomiyal kan dolaşımı enfeksiyonlarında kandidemiler 4. sırada yer almakta ve bunların %50’den fazlasında etken olarak C. albicans saptanmıştır. Ancak son yıllarda albicans dışı Candida’lar da artmaktadır. Özellikle yenidoğan ve cerrahi yoğun bakım birimlerinde C. parapsilosis’in ve C.glabrata’nın artan sıklıkla izole edildiği bildirilmektedir. Bu durum ampirik vekanıtlanmış antifungal seçimini etkilemektedir. Son çalışmalar, C. parapsilosis kandidemi insidansının %7-24 oranında arttığını göstermiştir. Özellikle invazif girişimlerin artışı, port ve benzeri kalıcı kataterlerin kullanımının yaygınlaşması, uzun yatış süreleri, antibiyotik kullanımının artması, total parenteral nutrisyon (TPN) desteklerinin çoğalması bu insidans artışı nedenleri arasında sayılmaktadır. C. parapsilosis’e bağlı kandidemilerde mortalite diğer kandidemilere göre düşük olsa da etken hastanede salgın yapabilir, yatış süresinin uzamasına, katater değişimine neden olabilir, en kısa sürede uygun ve etkili antifungal tedavi başlanmasını gerektirir. Kandidemilerde uygun, ampirik tedavinin bir an önce başlanmasının mortalite ve yatış süresini etkilediği bilinmektedir. Bu nedenle hastalarda kandidemi riskini, mortaliteyi etkileyen faktörleri belirlemek, etkenlerin tür tayini, duyarlılık profillerinin bilinmesi yararlıdır. Hastalarda uygun ve etkili tedaviye hızla başlanması için hastane veya bölümde epidemiyolojinin bilinmesi önemlidir. Ayrıca antifungal tedavilerin giderek yaygın kullanılması, dirençli etkenlerin ortaya çıkabilmesi, hasta profillerindeki değişim bu konularda yeni çalışmalara ihtiyaç doğurmaktadır. Bu çalışmanın amacı laboratuvarımızda, kan kültürlerinden izole edilen flukonazol dirençli C. parapsilosis tür kompleksi suşları arasında genotipik ilişki ve belirlenmesi ve bu suşlarla enfekte hastaların özellikleri ve klinik seyrinin incelenmesidir. Çalışmada 1997-2019 yılları arasında, flukonazol dirençli 88 C. parapsilosis kandidemisi tanılı hasta değerlendirildi. 30. gün mortalitesi %21.5 (n=19) olarak bulundu. Risk faktörlerine bakıldığında kemoterapi almanın iii mortaliyeti arttığı görüldü. İstatistiksel olarak santral venöz kateterin (SVK) çekilmesinin ve antifungal tedavi seçiminin mortalite üzerinde etkisi anlamlı bulunmadı. 88 suştan, izole edilebilen 47 suş genotipik olarak mikrosatellit yöntemi ile analiz edildi. Bu suşlar içinde, altı farklı genotip tespit edilmiş olup, en küçük ağaç yolu çizimi ve dendogram değerlendirilmesi neticesinde esas olarak iki farklı grup halinde kümelendikleri gösterilmiştir. Aynı dönemde, aynı klinikte yatan hastalarda aynı genotipe sahip etkenler tespit edilmiş ve etkenin endojen kaynaklı olmasından ziyade, çevre kaynaklı yayıldığı düşünülmüştür. Bu sonuçlar ile C. parapsilosis’e bağlı kandidemi görülen, genel durumu kötü ve altta yatan hastalıkları fazla olan hasta grubunda kataterlerin çekilmesinin bir süre ertelenebileceği, in vitro dirençli olmasına karşın flukonazol veya ekinokandin seçeneklerinin tedavide tercih edilebileceği, C. parapsilosis salgınlarından şüphelenildiği durumlarda salgın analizinde mikrosatellit analiz yönteminin uygun bir seçenek olarak düşünülebileceği gösterilmiştir.Candidemias take the 4th place in nosocomial bloodstream infections and C. albicans has been detected as the agent in more than 50% of them. However, in recent years, non-albicans Candida are also on the increase. It has been reported that C. parapsilosis and C. glabrata are isolated with increasing frequency, especially in neonatal and surgical intensive care units. This affects empirical and proven antifungal selection. Recent studies have shown that the incidence of C. parapsilosis candidemia increases by 7-24%. Especially the increase in invasive interventions, widespread use of ports and similar permanent catheters, long hospitalization periods, increased use of antibiotics, and the increase in total parenteral nutrition (TPN) support are among the reasons for this increase in incidence. Although mortality in candidemia due to C. parapsilosis is lower than other candidemias, the agent may cause an epidemic in the hospital, prolong the hospitalization period, cause catheter change, and require appropriate and effective antifungal treatment as soon as possible. It is known that initiating appropriate empirical treatment as soon as possible affects mortality and length of stay in candidemias. For this reason, it is useful to determine the risk of candidemia, the factors affecting mortality, the determination of the factors and their susceptibility profiles. It is important to know the epidemiology in the hospital or department for the rapid initiation of appropriate and effective treatment in patients. In addition, the widespread use of antifungal treatments, the emergence of resistant agents, and the change in patient profiles call for new studies on these issues. The aim of this study is to determine and determine the genotypic relationship between fluconazole-resistant C. parapsilosis strains isolated from v blood cultures in our laboratory, and to examine the characteristics and clinical course of patients infected with these strains. Eighty-eight fluconazole-resistant patients diagnosed with C. parapsilosis candidemia between 1997 and 2019 were evaluated in the study. 30th day mortality was found as 21.5% (n = 19). Considering the risk factors, it was seen that the mortality of receiving chemotherapy increased. Statistically, the effect of withdrawal of central venous catheter (CVC) and choice of antifungal therapy on mortality was not significant. 47 strains that can be isolated from 88 strains were genotypically analyzed by microsatellite method. Six different genotypes were identified among these strains, and it was shown that they were clustered in two different groups as a result of the smallest tree path drawing and dendogram evaluation. In the same period, factors with the same genotype were identified in patients hospitalized in the same clinic and it was thought that the agent was spread by environmental rather than endogenous origin. With these results, the withdrawal of catheters may be delayed for a while in the patient group with candidemia due to C. parapsilosis, whose general condition is poor and with high underlying diseases, fluconazole or echinocandin treatment may be preferred for treatment despite in vitro resistance, and in epidemic analysis in cases where C. parapsilosis outbreaks are suspected. It has been shown that microsatellite analysis method can be considered as a suitable option
Evaluation of YouTube Videos on HIV/AIDS: A Critical Analysis of Content Quality and Reliability
No full textHIV and AIDS remain as significant global health issues, with misinformation and stigma surrounding the diseases still being prevalent. Accurate and reliable information is crucial for promoting prevention, early detection, and effective management of the disease. YouTube has emerged as a popular platform for sharing and consuming health-related content, but the quality and reliability of its videos on various health topics have been questioned. Objective: This study aims to systematically review and evaluate the quality and reliability of YouTube videos on HIV/AIDS. Methods: We searched for videos on YouTube using two search terms, "HIV" and "AIDS," and evaluated the top 100 videos for each search term. We recorded video features such as length, likes, comments, views, and upload date. Two independent evaluators assessed the videos' quality and reliability using the Global Quality Scale and the modified DISCERN tool. We classified the videos into two groups based on the source that uploaded the video, professional and non-professional, and analyzed the data using statistical methods. Results: Of the 159 videos evaluated, the most common content categories were HIV transmission routes, basic information and definition of HIV, and HIV/AIDS activism and awareness. Non-professional videos tended to be shorter, but there were no significant differences in views, likes, and likes per day counts. Comments were significantly higher in non-professional videos. Professional videos had higher quality and reliability scores than non-professional videos. Conclusion: Accurate and reliable information on HIV/AIDS is critical for promoting prevention, early detection, and effective management of the disease. YouTube has the potential to disseminate this information, but the quality and reliability of its videos must be improved. Our study highlights the need to prioritize professional, high-quality, and reliable video content on HIV/AIDS on YouTube to improve the public health outcome
Estimation of Exterior Parameters of Sensor Combination for Efficient 3D Modeling
No full textISPRS-Commission V Mid-Term Symposium on Close Range Image Measurement Technique -- JUN 21-24, 2010 -- Newcastle upon Tyne, ENGLANDLaser scanning is the latest method to collect 3D spatial data and modelling. It becomes more and more popular in engineering applications such as 3D modeling, deformation analysis, reverse engineering and urban planning. However, laser scanners are not sufficient on their own for 3D surveying and modeling. It should be used together with the photogrammetric data especially in the orientation of point clouds, measurement of the non-scanning areas, and texture mapping. This task needs the combination of range sensor and image sensor. The sensor combination like this is a very efficient and flexible system for close-range measurement applications. Most of the laser scanners include integrated camera but most of them are low resolution and they can not be removed independent from the scanner. Therefore high resolution camera should be mounted to the laser scanner. In this study we consider mounting a camera onto laser scanner and estimating exterior parameters with strong control methods. We also made experimental studies by using exterior parameters.ISPRS CommissScientific and Technological Research Council of Turkey ( TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); "Foreign Research Scholarship Program" to Cihan ALTUNTAS; Vienna University of Technology; Scientific Research Found of The Selcuk University ( BAP)We would like to thank The Scientific and Technological Research Council of Turkey ( TUBITAK) for the financial support they have provided as a part of "Foreign Research Scholarship Program" to Cihan ALTUNTAS to the carried out this study in Vienna University of Technology. In addition author Cihan ALTUNTAS thanks Scientific Research Found of The Selcuk University ( BAP) to financial support to attend this scientific event
Phase transitions, elastic and electronic properties of hydrogen storage Na2PdH4
No full textHydrogen can be absorbed by some materials at specific pressures and temperatures. This is extremely important in terms of creating carbon-free and sustainable society. In this work hydrides are good candidates to fulfill these aims. Electronic and magnetic properties of hydrides are investigated. This study considers Na2PdH4 as solid storage of hydrogen material. Hydrogen is highly soluble in palladium and can be stored in large amounts at ambient conditions. The structural evolution, electronic and elastic properties of Na2PdH4 has been investigated by means of density functional theory. The SIESTA software package is used with the generalized gradient approximation for the exchange-correlation functional and norm-conserving Troullier-Martins pseudopotentials. High-pressure computations have been carried out to reveal phase transitions. Na2PdH4 is transformed from I4/mmm tetragonal structure to Immm orthorhombic structure at 100 GPa. The electronic band structures and density of states are obtained for both phases. Mechanical stability is analyzed using the elastic constants. Moreover, several parameters such as Young's modulus, shear modulus, and their ratios are obtained and discussed. © 2021 Author(s)
Decentralized multi-agent path finding framework and strategies based on automated negotiation
No full textThis paper introduces a negotiation framework to solve the Multi-Agent Path Finding (MAPF) Problem for self-interested agents in a decentralized fashion. The framework aims to achieve a good trade-off between the privacy of the agents and the effectiveness of solutions. Accordingly, a token-based bilateral negotiation protocol and two negotiation strategies are presented. The experimental results over four different settings of the MAPF problem show that the proposed approach could find conflict-free path solutions albeit suboptimally, especially when the search space is large and high-density. In contrast, Explicit Estimation Conflict-Based Search (EECBS) struggles to find optimal solutions. Besides, deploying a sophisticated negotiation strategy that utilizes information about local density for generating alternative paths can yield remarkably better solution performance in this negotiation framework.Interactive Intelligenc
A Pedagogical Stylistic Study of “Eleven” by Sandra Cisneros
No full textKnowing about the linguistic and stylistic features of any literary texts in general and the aspect of lexical pattern in particular, concerning the way through which the author uses adjectives, verbs, nouns and adverbs provide us with precious information that can be helpful in judging about the appropriateness of the text to be used for a specific purpose such as teaching to EFL students in a specific level. Therefore, according to the importance of this issue, and based on the checklist of linguistic and stylistic categories proposed by Leech and Short (2000), the stylistic analysis of the short story entitled “Eleven” written by Sandra Cisneros was performed in this study from the lexical category dimension. In the end, the results and findings of the study are elaborated and discussed, with the conclusion that the author was successful in using the appropriate diction and linguistic features to express her main points from the tongue of an Eleven-year-old kid who is also ten, nine, eight, seven, six, five, four, two and one year old.
Key words: Lexical category, Eleven, Stylistic analysis, EFL, Short stor
Risk factors and outcome for bloodstream infections due to fluconazole-resistant <i>candida parapsilosis</i>: A 22-year single-center retrospective study
No full textCandidemia ranks among the top causes of nosocomial bloodstream infections, significantly increasing hospital stays and costs. Rapid and effective empirical antifungal therapy is crucial. The Candida parapsilosis species complex, the second most common cause of candidemia, has shown rising fluconazole resistance globally and in our country. Additionally, echinocandins exhibit higher minimum inhibitory concentrations (MICs) for C. parapsilosis, complicating empirical treatment decisions. This retrospective study analyzed 173 C. parapsilosis candidemia cases over 22 years in a tertiary care hospital. We compared 88 fluconazole non-susceptible (minimum inhibitory concentration [MIC] = 4 mu g/mL: susceptible dose dependent; MIC >= 8 mu g/ml resistant) and 85 fluconazole susceptible cases, examining demographics, clinical characteristics, risk factors, and 28-day mortality. Independent risk factors for fluconazole non-susceptibilty included age >= 66 years (p = 0.016), central venous catheter use (p < 0.001), total parenteral nutrition (p = 0.003), and colostomy (p = 0.049). Fluconazole non-susceptible cases had lower microbiological cure rates and higher mortality. Mortality in this group was independently associated with microbiological cure failure (p < 0.001). This study highlights the importance of identifying risk factors to estimate the likelihood of resistant pathogens, initiating targeted antifungal therapy, and providing individualized management. Monitoring local resistance patterns is essential to guide empirical therapy. Further multicenter research is needed to validate findings and optimize treatment for fluconazole resistant candidemia
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