1,721,036 research outputs found

    Advances on Applications of Bioactive Natural Compounds

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    Natural compounds, from terrestrial and marine sources, are the result of an evolutionary process which originated in compounds with great structural diversity, multiple biological activities and miscellaneous applications. A large and very active research field is dedicated to identifying biosynthesized compounds; to improve/develop new methodologies to produce/reuse natural compounds; to assess their potential; and to understand their mechanism of action. This Special Issue brings together excellent original and review works, focused on the most recent advances related to the secondary metabolites’ composition of natural sources, and the proposal of new applications for their constituents, such as therapeutic agents, and pesticides or food ingredients

    Advances on Applications of Bioactive Natural Compounds

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    Natural compounds, from terrestrial and marine sources, are the result of an evolutionary process which originated in compounds with great structural diversity, multiple biological activities and miscellaneous applications. A large and very active research field is dedicated to identifying biosynthesized compounds; to improve/develop new methodologies to produce/reuse natural compounds; to assess their potential; and to understand their mechanism of action. This Special Issue brings together excellent original and review works, focused on the most recent advances related to the secondary metabolites’ composition of natural sources, and the proposal of new applications for their constituents, such as therapeutic agents, and pesticides or food ingredients

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Salicornia ramosissima J. Woods: estudo fitoquímico das partes aéreas

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    Mestrado em Química - Química Orgânica e Produtos NaturaisSalicornia ramosissima J. Woods (purple glasswort na Inglaterra ou erva salada em Portugal e Espanha) é uma planta do género Salicornia L. (Chenopodiaceae). Esta planta é uma halófita que se desenvolve em zonas marinhas, sendo encontrada abundantemente no sapal da Ria de Aveiro. As plantas do género Salicornia são utilizadas pelos humanos desde a antiguidade, quer como alimento, quer na medicina tradicional. As plantas deste género são responsáveis por atividades biológicas, tais como antioxidante, anti-hiperlipidémica, anti-hiperglicémica, antiproliferativa, antifúngica, antibacteriana e moduladora do sistema imunitário. Contudo, relativamente à espécie S. ramosissima pouco se conhece. No âmbito deste trabalho estudou-se o extrato de hexano das partes aéreas de S. ramosissima, por GC-MS. Foram detetados e quantificados 57 compostos, maioritariamente, ácidos gordos saturados, insaturados, álcoois de cadeia longa e esteróis. Neste estudo avaliou-se, também, a influência que a quantidade de água utilizada na irrigação tem na produção de compostos lipofílicos. Detetou-se que, quando a planta é irrigada em excesso, há um aumento na produção de ésteres principalmente os que envolvem ácidos gordos saturados e diácidos, estando estes últimos quase exclusivamente na forma esterificada. Estudou-se também o extrato de diclorometano das partes aéreas de S. ramosissima. Foram isolados e caracterizados dois novos compostos naturais, aos quais foram atribuídos os nomes triviais saliramofenol e saliramoester. Simultaneamente foi possível isolar e caracterizar a escopoletina pela primeira vez na espécie S. ramosissima e quatro compostos pela primeira vez no género Salicornia, o 2-hidroxicinamato de etilo, o (E)- ferulato de octadecanilo, o (E)-ferulato de eicosanilo e o triglicérido do ácido tetracosanóico.Salicornia ramosissima J. Woods (purple glasswort in England or herb salad in Portugal and Spain) is a Salicornia L. genus (Chenopodiaceae) plant. It’s an halophyte that develops in marine zones, wildly spread in Ria de Aveiro. Plants of the Salicornia genus are used by humans as food or traditional medicine since ancient times. Plants of this genus are responsible for biological activities such as antioxidant, anti-hyperlipidemic, antihyperglycemic, antiproliferative, antifungal, antibacterial and immune system modulator. However, for the S. ramosissima little is known. Within this work we studied the hexane extract of the aerial parts of S. ramosissima, by GC-MS. We detected and quantified 57 compounds mainly saturated and unsaturated fatty acids, long chain alcohols and sterols. In this study was also evaluated the influence that the amount of water used in the irrigation has in the production of aliphatic compounds in the plant and, when excessively irrigated, it was detected an increase in the production of esters especially those involving saturated fatty acids and diacids, the latter being almost exclusively in esterified form. On the other hand, were also isolated from the S. ramosissima aerial parts dichloromethane extract and characterized two new natural compounds, named saliramophenol and saliramoester. Furthermore, were also isolated and characterized scopoletine for the first time in S. ramosissima and four compounds new in the Salicornia genus, ethyl 2-hydroxycinnamate, octadecanyl (E)-ferulate, eicosanyl (E)-ferulate and triacylglycerol tetracosanoic acid

    Biological Activity and Applications of Natural Compounds

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    Nature represents an amazing source of inspiration, since it produces a great diversity of natural compounds selected by evolution, which exhibit multiple biological activities and applications. A large and very active research field is dedicated to identifying biosynthesized compounds, to improve/develop new methodologies, to produce/reuse natural compounds, and to assess their potential for pharmaceutical, cosmetic and food industries, among others, and additionally, to understand their mechanism of action. This book is dedicated to presenting the most recent results on the development of natural compounds’ applications. Ten original research works, organized by applications, and two reviews are included. Each of them contributes to the knowledge advance, insofar as they present new applications for known products, new methodologies to obtain new products, or the evaluation of a given application, with the applications related to health promotion being the most frequently considered. These works are significant contributions and reinforce the dynamic field of natural products’ applications

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Avaliação 2014-16- CQ : Ana Maria Loureiro da Seca : comprovativos

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    Neste registo estão os comprovativos referentes à avaliação de docentes 2014-2016 que não cabem em nenhuma das outras coleções mas que são indispensáveis no processo de avaliação e são apenas acessíveis à Comissão de Avaliação da Unidade Orgânica DCFQE.Neste registo estão os comprovativos referentes à avaliação de docentes 2014-2016 que não cabem em nenhuma das outras coleções mas que são indispensáveis no processo de avaliação e são apenas acessíveis à Comissão de Avaliação da Unidade Orgânica DCFQE.N/

    Tabela Periódica: a composição química do universo num quadro com 18 colunas e 7 linhas

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    Coordenação e edição de Ana Teresa Alves (FCSH-UAc).De que é feito tudo o que existe no universo? Pode parecer mentira, mas a resposta a esta questão é curta: No universo existem apenas 91 elementos químicos diferentes (substâncias puras que não podem ser separadas em substâncias mais simples). Tudo o que existe no universo é composto por um ou mais elementos de entre estes 91. Queres saber quais são? Então olha para uma tabela periódica!info:eu-repo/semantics/publishedVersio
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