384 research outputs found

    Computational Fluid Dynamics and Numeric Analysis of Aortic Wall Shear Stress Alterations Induced by Fatty Streaks

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    Atherosclerosis, a disease of the large arteries, is the primary cause of heart disease and stroke. It often begins with the formation of fatty streaks (FS). The FS consists of subendothelial accumulations of cholesterol-engorged macrophages, called ‘foam cells’. For this to happen, there needs to be a significant change in the permeability of the endothelial layer. Considering the established influence of mechanical stresses on endothelial properties, shear stress can increase the permeability of the endothelial layer. This study employs a hybrid approach, combining computational fluid dynamics (CFD) simulation with numerical analysis, on a simplified model of the aorta to Investigate Endothelial Shear Stress (ESS) changes in the FS. Our findings reveal that the presence of FS leads to quantitative changes in ESS. Further numerical analysis in MATLAB 9.14 suggests a pattern that metaphorically resembles a dam, potentially trapping ‘foam cells’. In an additional aspect of this study, our findings suggest that an increase in blood flow could potentially counteract the permeability increase, thus acting as a preventative measure against atherosclerosis progression. These results underscore the importance of early intervention strategies to mitigate atherosclerosis progression

    Author Correction: A portrait of the Higgs boson by the CMS experiment ten years after the discovery

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    In the version of this article initially published, CMS Collaboration author names, affiliations and acknowledgements were omitted and have now been included in the HTML and PDF versions of the article.Publisher versio

    A fault tolerant system using collaborative agents

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    14th Turkish Symposium on Artificial Intelligence and Neural Networks -- JUN 16-17, 2005 -- Izmir, TURKEYReplication of data or processes is an effective way to provide enhanced performance, high availability and fault tolerance in distributed systems. For instance, in systems based on the client-server model, a server may serve many clients and because of heavy loads, the server cannot respond to the requests on time. In such a case, replicating data or servers may improve performance. Moreover, data and processes can be replicated to protect against failures. However, this is a very complex procedure. In this paper, I propose a method, to make systems fault tolerant based on replication, by way of exploiting the use of collaborative agents. This method is also used to improve fault tolerance in multi-agent systems.Izmir Inst Technol, EE & CE Depts, Turkish Sci & Res Council, Izmir Branch Chamber Elect & Elect Engineer

    Erratum to: Vinpocetine and Vasoactive Intestinal Peptide Attenuate Manganese-Induced Toxicity in NE-4C Cells (Biol Trace Elem Res (2016), 10.1007/s12011-016-0742-z)

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    In the above-mentioned article, the author names Mumin Alper Erdogan and Saylav Bora were written incorrectly as Alper Mümin Erdoğan and Ejder Saylav Bora, respectively. However, these errors have been already corrected in both the referenced article and in the author listing for this article. The authors regret the oversight. © 2016, Springer Science+Business Media New York

    Bora Baruh: katalog

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    "Toliko su teškim i tragičnim životom živovali mnogi naši umjetnici i srednje i starije i još starije generacije da bi i nastanak i nestanak Bore Baruha mogao da se shvati kao uobičajena pojava. To bi značilo da je i on na određen način zahvaćen jednim od onih ciklusa koji su kod nas često nailazili i kosili u talasima, da su mogli ostaviti i ostavljali su dubljih tragova u našoj likovnoj umjetnosti. Neimaština, nesporazumi, probijanja kroz život, odlasci na studije u nepoznate, u mašti priželjkivane, zemlje, borba za održanje egzistencije, bolesti koje su odnosile mladosti, zatvori koji su na silu zaustavljali tokove, ratovi - sve su to nemilosrdni faktori koji su razrješavali i određivali decenijama tolike sudbine. Kao i mnoge druge velike i plemenite ličnosti oni nisu mimoišli ni Boru Baruha. A ipak u njegovom slučaju neke pojave su tako specifične. Događaji, koji su ga pratili tokom kratkog života i oni koji su došli poslije, bili su više nego surovi. Sve teškoće života iskusio je na sebi Bora, a djela koja su ostala iza njega kao da nastavljaju sudbinu svoga autora. Ne zna se koliko je Bora Baruh izvajao portreta, naslikao ulja, akvarela, crteža i skica. Zna se da je prije odlaska u partizane ostavio poruku da ako se ne vrati treba njegova djela predati nekoj kulturnoj ustanovi, muzeju, domu kulture. I to je učinjeno. Danas je, međutim, samo spisak od 106 ulja i akvarela u posjedu porodice, dok se za veliku većinu radova više ne zna gdje su...""Many of our artists of the middle and older and even older generations lived such a difficult and tragic life that the emergence and disappearance of Bora Baruch could be understood as a common phenomenon. This would mean that he too was in a certain way affected by one of those cycles that often came across us and cut in waves, that they could leave and did leave deeper traces in our fine art. Poverty, misunderstandings, breaking through life, going to study in unknown places, in the imagination, desired countries, the struggle to maintain existence, diseases that took away youth, prisons that forcibly stopped the flow, wars - all these are merciless factors that resolved and determined so many destinies for decades. Like many other great and noble personalities, they did not pass by even Bora Baruh. And yet in his case, some phenomena are so specific. The events, which followed him during his short life and those that came after, were more than cruel. All the hardships of life he experienced on himself Bora, and the works that remained behind him seem to continue the destiny of their author. It is unknown how many portraits, oil paintings, watercolours, drawings and sketches Bora Baruh sculpted. It is known that before leaving for the partisans, he left a message that if he did not return, his works should be handed over to a cultural institution, museum, or cultural centre. And it was done. Today, however, only a list of 106 oils and watercolours is in the family's possession, while for most artworks no longer know where they are...

    Bora event variability and the role of air-sea feedback

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    Author Posting. © American Geophysical Union, 2007. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 112 (2007): C03S18, doi:10.1029/2006JC003726.A two-way interacting high resolution numerical simulation of the Adriatic Sea using the Navy Coastal Ocean Model (NCOM) and Coupled Ocean/Atmosphere Mesoscale Prediction System (COAMPS®) was conducted to improve forecast momentum and heat flux fields, and to evaluate surface flux field differences for two consecutive bora events during February 2003. (COAMPS® is a registered trademark of the Naval Research Laboratory.) The strength, mean positions and extensions of the bora jets, and the atmospheric conditions driving them varied considerably between the two events. Bora 1 had 62% stronger heat flux and 51% larger momentum flux than bora 2. The latter displayed much greater diurnal variability characterized by inertial oscillations and the early morning strengthening of a west Adriatic barrier jet, beneath which a stronger west Adriatic ocean current developed. Elsewhere, surface ocean current differences between the two events were directly related to differences in wind stress curl generated by the position and strength of the individual bora jets. The mean heat flux bias was reduced by 72%, and heat flux RMSE reduced by 30% on average at four instrumented over-water sites in the two-way coupled simulation relative to the uncoupled control. Largest reductions in wind stress were found in the bora jets, while the biggest reductions in heat flux were found along the north and west coasts of the Adriatic. In bora 2, SST gradients impacted the wind stress curl along the north and west coasts, and in bora 1 wind stress curl was sensitive to the Istrian front position and strength. The two-way coupled simulation produced diminished surface current speeds of ∼12% over the northern Adriatic during both bora compared with a one-way coupled simulation.The research support for J. Pullen, J. D. Doyle, and T. Haack was provided by the Office of Naval Research (ONR) program elements 0602435N and 0601153N

    Optimal maintenance of semi-markov missions

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    Çekyay, Bora (Dogus Author)We analyze optimal replacement and repair problems of semi-Markov missions that are composed of phases with random sequence and durations. The mission process is the minimal semi-Markov process associated with a Markov renewal process. The system is a complex one consisting of non-identical components whose failure properties depend on the mission process. We prove some monotonicity properties for the optimal replacement policy and analyze the optimal repair problem under different cost structures

    EXPLOITING THE USE OF COOPERATION IN SELF-ORGANIZING RELIABLE MULTIAGENT SYSTEMS

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    In this paper, a novel and cooperative approach is exploited introducing a self-organizing engine to achieve high reliability and availability in multiagent systems. The Adaptive Multiagent Systems theory is applied to design adaptive groups of agents in order to build reliable multiagent systems. According to this theory, adaptiveness is achieved via the cooperative behaviors of agents and their ability to change the communication links autonomously. In this approach, there is not a centralized control mechanism in the multiagent system and there is no need of global knowledge of the system to achieve reliability. This approach was implemented to demonstrate its performance gain in a set of experiments performed under different operating conditions. The experimental results illustrate the effectiveness of this approach

    Implementing Fault-Tolerant Services in Goal-Oriented Multi-Agent Systems

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    In this paper, findings and analysis detail the implementation of fault tolerance services into a goal-oriented multi-agent systems development platform. Fault tolerance services are used to provide replication-based fault tolerance policies (i.e. static and adaptive) to multi-agent systems. This approach provided flexibility and reusability to multi-agent systems because fault tolerance policies were implemented as reusable plan structures. Thus, whenever an agent was needed to be made fault-tolerant, plans for fault tolerance policies were simply activated by sending a request message

    High-resolution mapping of Bora winds in the northern Adriatic Sea using synthetic aperture radar

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    Author Posting. © American Geophysical Union, 2010. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 115 (2010): C04020, doi:10.1029/2009JC005524.The Adriatic Sea is regularly subjected to strong Bora wind events from the northeast during winter. The events have a strong effect on the oceanography in the Adriatic, driving basin-scale gyres that determine the transport of biogeochemical material and extracting large amounts of heat. The Bora is known to have multiple surface wind jets linked to the surrounding orography and have been the focus of many studies, but it has not been possible to describe the detailed spatial structure of these jets by in situ observations. Using high-resolution spaceborne RADARSAT-1 synthetic aperture radar (SAR) images collected during an active Bora period (23 January–16 February 2003), we created a series of high-resolution (300 m) maps of the wind field. The obtained winds show reasonable agreement with several in situ wind observations, with an RMS wind speed error of 3.6 m/s, slightly higher than the 2–3 m/s errors reported in previous studies. These SAR images reveal the spatial structure of the Bora wind in unprecedented detail, showing several new features. In the Senj region of Croatia, several images show rhythmic structure with wavelengths of 2–3 km that may reflect Bora pulsation seen at fixed locations by previous investigators. Along the Italian coast, several images show a wide (20–30 km) band of northwesterly winds that abruptly change to the northeasterly Bora winds further offshore. Meteorological model results suggest that these northwesterly winds are consistent with those of a barrier jet forming along the Italian Apennine mountain chain
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