1,720,971 research outputs found
Effects of n-Octyl-β-D-Glucopyranoside on Human and Rat Erythrocyte Membrane Stability against Hemolysis
Full text linkThe practical importance for the pharmaceutical and cosmetics industries of the interactions between biological membranes and surfactant molecules has led to intensive research within this area. The interactions of non-ionic surfactant n-octyl-β-D-glucopyranoside (OG) with the human and rat erythrocyte membranes were studied. The in vitro hemolytic and antihemolytic activities were determined by employing a method in which both erythrocytes were added to the hypotonic medium containing OG at different concentrations, and the amount of haemoglobin released was determined. n-octyl-β-D-glucopyranoside was found to have a biphasic effect on both types of erythrocyte membrane. We also investigated the interactions of OG with the erythrocyte membrane in isotonic medium; the dose-dependent curves show similar behaviour in both human and rat erythrocytes. Our results showed that OG has greater antihemolytic potency on rat than on human erythrocytes; furthermore, rat erythrocytes were more sensitive than human erythrocytes to hypotonic shock. How the different lipoprotein structure of these erythrocytes determines a difference in antihemolytic activity is discussed
Liver antioxidant enzyme stimulation by acute cadmium intoxication is independent of lipid peroxidation
No full textEffect of cadmium or manganese administration on liver glutathione-S-transferase activity and alpha GST levels
No full textEffect of cadmium or manganese administration on liver glutathione S-transferase activity and alpha GST levels
No full textANTIOXIDANT EFFECT OF HYDROXYTYROSOL (DPE) AND MN2+ IN LIVER OF CADMIUM-INTOXICATED RATS
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Antioxidant effect of hydroxyltyrosol (DPE) and Mn2+ in liver of cadmium-intoxicated rats
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