148,275 research outputs found
Non-obese T2DM Machine Learning Analysis
No full textNational Family Health Survey-4 (NFHS-4):
The NFHS-4 datasets were downloaded from The Demographic & Health Surveys (DHS) Program website (https://www.dhsprogram.com/) and prepared for final analysis. The final version has been uploaded here only.
Clinical, Anthropometric and Biochemical (CAB) Survey 2014:
The CAB Survey 2014 dataset was downloaded from the Open Government Date (OGD) Platform India website (https://data.gov.in/)..The final version prepared after cleaning has been uploaded here.
Community Health Cohort:
The community health cohort included 714 subjects (257 males and 457 females) recruited from a community-based Metabolic Health Screening Program named “From Food to Nutrition Security” [Sarkar J, Maity SK, Sen A, Nargis T, Ray D, Chakrabarti P (2019) Impaired compensatory hyperinsulinemia among nonobese type 2 diabetes patients: a cross-sectional study. TherAdvEndocrinolMetab 10:204201881988902. http://doi:10.1177/2042018819889024]. 221 treatment naive T2DM patients and 493 healthy controls were recruited for blood sample collection and anthropometric measurements (Height, Weight and Waist Circumference)
Non-obese T2DM Machine Learning Analysis
No full textNational Family Health Survey-4 (NFHS-4):
The NFHS-4 datasets were downloaded from The Demographic & Health Surveys (DHS) Program website (https://www.dhsprogram.com/) and prepared for final analysis. The final version has been uploaded here only.
Clinical, Anthropometric and Biochemical (CAB) Survey 2014:
The CAB Survey 2014 dataset was downloaded from the Open Government Date (OGD) Platform India website (https://data.gov.in/)..The final version prepared after cleaning has been uploaded here.
Community Health Cohort:
The community health cohort included 714 subjects (257 males and 457 females) recruited from a community-based Metabolic Health Screening Program named “From Food to Nutrition Security” [Sarkar J, Maity SK, Sen A, Nargis T, Ray D, Chakrabarti P (2019) Impaired compensatory hyperinsulinemia among nonobese type 2 diabetes patients: a cross-sectional study. TherAdvEndocrinolMetab 10:204201881988902. http://doi:10.1177/2042018819889024]. 221 treatment naive T2DM patients and 493 healthy controls were recruited for blood sample collection and anthropometric measurements (Height, Weight and Waist Circumference)
Tegonotus fisus Chakrabarti & Sarkar, 2011, n. sp.
No full textTegonotus fisus n. sp. (Figs. 11–16.) Diagnosis. This species is distinguished by the following combination of characters: numerous irregular broken lines on prodorsal shield, frontal lobe of prodorsal shield has clear median and admedian lines, bifurcated dorsal pedipalp genual setae d, scapular tubercles much ahead of the posterior shield margin, seta on tibia I absent, 4 rayed, tarsal empodium, presence of two types of ventral annuli i.e. first 14–16 ventral annuli with microtubercles and rest of the ventral annuli with microstriations, both the coxae smooth, proximal region of female genitalia has small striations, two horn like lateral projections emerge from mid lateral margin of epigynium. FEMALE (n= 10): Body 169.9 (165.4–169.9) long, 56.0 (55.2 –56.0) wide. Gnathosoma 23.3 (22.3–23.3) long, curved down, dorsal pedipalp genual seta d bifurcated and 9.3 (9.1–9.3). Prodorsal shield 65.3 (64.8–65.3) long, 56.0 (55.2 –56.0) wide with a prominent shield lobe of 19.6 (18.6–19.6) long over the base of gnathosoma, frontal shield lobe triangular, with distinct median and admedian lines and numerous broken lines; prodorsal shield shows granulations and a prominent ‘V’ shaped mark extended from anterior shield margin up to middle encompassing prominent median line, faint impressions of median and admedian lines are found below the ‘V’ mark, numerous broken lines are also found at two lateral sides of prodorsal shield, near the base of each dorsal tubercle small semicircular arcs are found. Scapular tubercles 13.0 (12.6 –13.0) conspicuous, ahead of rear shield margin and 26.1 (26.1–26.9) apart, scapular seta sc 2.8 (2.1–2.8) and directed upward and centrad. Leg I from base of trochanter 25.2 (24.2–25.2); femur 10.2 (10.2–11.2), basiventral femoral seta bv 9.3 (8.9–9.3); genu 3.7 (3.7–4.2) with antaxial genual seta 1 ʺ 28.0 (27.0–28.0); tibia 6.5 (5.6–6.5) without paraxial tibial seta 1 ʹ; tarsus 4.6 (3.7–4.6); two identical tarsal setae-paraxial fastigial tarsal setae ft ʹ and antaxial fastigial tarsal seta ft ʺ 14.0 (11.3 –14.0); paraxial unguinal tarsal seta u ʹ 3.7 (2.6–3.7), tarsal solenidion ω curved, knobbed and 4.6 (3.7–4.6), 4 rayed, tarsal empodium em 3.7 (3.7–4.4). Leg II from base of trochanter 24.2 (23.2–24.2); femur 10.2 (10.2–11.2), basiventral femoral seta bv 9.3 (8.9–9.3), genu 3.7 (3.7–4.2) with antaxial genual seta 1 ʺ 28.0 (27.0–28.0); tibia 5.6 (4.5–5.6) without paraxial tibial seta 1 ʹ; tarsus 3.7 (3.7–4.2) with two identical tarsal setae-paraxial fastigial tarsal setae ft ʹ and antaxial fastigial tarsal seta ft ʺ 14.0 (11.3 –14.0), paraxial unguinal tarsal seta u ʹ 2.8 (2.1–2.8), tarsal solenidion ω curved, knobbed and 4.6 (4.1–4.6); 4 rayed, tarsal empodium em 3.7 (3.7–4.4). Coxae I 18.6 (17.5–18.6) long, smooth and contiguous with a mid sternal line, seta 1 b 6.5 (5.6–6.5) and 5.9 (5.1–5.9) apart; 1 a tubercles with seta present a little ahead of line across the 2 a tubercles; seta 1 a 14.0 (13.0–14.0) and 6.9 (6.1–6.9) apart, the distance between setae 1 a and 1 b is 6.2 (6.2–6.4); coxa II smooth, 13.0 (13.0– 13.8), seta 2a 29.8 (28.8–29.8) and 23.6 (22.8–23.6) apart. Opisthosoma with 29 (28–29) smooth dorsal annuli and 56 (56–57) narrow ventral annuli, micro tubercles rounded and located on first 15 (14–16) ventral annuli; rest of the ventral annuli starting from posterior margin of genitalia up to last ventral annulus have microstriations, seta c 2 15.8 (14.9–15.8) on annulus 15 (14–15), seta d 52.2 (52.2–53.2) on annulus 23 (23–24); seta e 4.6 (4.6–5.6) on ventral annulus 29 (28–29); seta f 14.0 (14.0– 14.9) on ventral annulus 49 (48–49); seta h 1 absent, seta h 2 42.0 (42.0– 43.2). Epigynium 16.8 (16.8– 17.5) long, 19.6 (19.6–21.1) wide; smooth except small striations at anterior margin, two horn like lateral projections emerge from mid lateral margin of epigynium; seta 3a 12.1 (10.2–12.1). MALE. Not observed. Type material. Holotype: Female (marked) on slide (no. 1378 / 91 / 2006), India: West Bengal: Malda, Amriti, Latitude: 24 ° 20 ʹ 38 ʺ N and Longitude: 87 °05ʹ 29 ʺ E, 24 December, 2006 from Mangifera indica (L.) (Anacardiaceae), Coll. S. Sarkar. Paratypes: 8 females on slide bearing holotype and 49 females on 6 slides (nos. 1376- 1377 / 91 / 2006 and 1379-1382 / 91 / 2006); collection data same as in holotype. Relation to host. Pinkish brown, fusiform mites are vagrants on the undersurface of the leaves. Etymology. The specific epithet ‘ fisus ’, a Latin word, meaning split, and refers to the bifurcate dorsal pedipalp genual seta. Remarks. The new species resembles T. schleicherae Ghosh & Chakrabarti, 1985, T. ferrugeniae Mohanasundaram, 1985, T. tricarinatus Fletchmann, 1996 in having 4 rayed tarsal empodium and scapular tubercles much above the shield margin. However, it differs from T. schleicherae by not having granulated prodorsal shield, from T. ferrugeniae by not having lateral spine of dorsal annuli and from T. tricarinatus in overall prodorsal shield structure, shorter setae 3 a and smooth coxae. The new species also closely resembles T. convolvuli (Channabasavanna, 1966) in location of scapular seta well ahead of rear margin of prodorsal shield and having 4 rayed tarsal empodium but differs from it by having numerous irregular broken lines on prodorsal shield besides bifurcated dorsal pedipalp genual setae and not having seta on tibia I.Published as part of Chakrabarti, Samiran & Sarkar, Sanjay, 2011, Three new species of eriophyoid mites (Acari: Eriophyoidea) infesting fruit yielding plants from India, pp. 28-36 in Zootaxa 2988 on page 34, DOI: 10.5281/zenodo.20372
Aculops spodiasis Chakrabarti & Sarkar, 2011, n. sp.
No full textAculops spodiasis n. sp. (Figs. 1–6.) Diagnosis. This species is distinguished by the following combination of characters: scapular tubercles with setae located almost at posterior margin of prodorsal shield, presence of incomplete median line, non granular prodorsal shield margin, prodorsal shield shows symmetrical cells and lines, presence of 7 columnar cells at anterior margin of prodorsal shield, 5 rayed tarsal empodium, smooth dorsal annuli, h 1 seta present, surface of coxa I ornamented with curved lines where as that of coxa II is almost smooth except two curved parallel lines at distal ends, 1 b tubercles with setae located ahead of anterior coxal approximation, epigynium is almost smooth except a median sinuate line. FEMALE (n= 10): Body 140.9 (139.8–140.9) long, 60.6 (58.3–61.2) wide. Gnathosoma 17.2 (15.2–17.2) long, curved down, dorsal pedipalp genual seta d 5.6 (5.3–5.9). Prodorsal shield 40.1 (40.1–41.2) long, 56.0 (55.3 –56.0) wide, nongranular and with an acuminate shield lobe; anterolateral region of prodorsal shield shows 7 columnar cells running parallel to each others, between the lateral margin of prodorsal shield and submedian line there are 2 cells of unequal size, median line incomplete and present only on rear end, two carinae from the admedian line meet the anterior tip of the median line, admedian lines complete, sinuate and connected with each others at two sites by transverse lines, the transverse connection between admedian line at middle region has two lateral extensions, submedian lines sinuate, diverge and bifurcate above the base of dorsal tubercles, dorsal tubercles almost on rear shield margin, scapular seta sc 4.5 (4.5–5.6). Leg I from base of trochanter 43.8 (43.8–44.8); femur 10.2 (10.2–11.2), basiventral femoral seta bv 11.2 (9.3–11.2); genu 5.6 (5.1–5.6), antaxial genual seta 1 ʺ 14.9 (14.9–15.8); tibia 5.6 (5.6–6.5), paraxial tibial seta 1 ʹ 3.7 (3.7–4.1); tarsus 6.5 (5.6–6.5); paraxial fastigial tarsal setae ft ʹ 17.7 (16.9–17.7), antaxial fastigial tarsal seta ft ʺ 14.0 (13.9 –14.0); paraxial unguinal tarsal seta u ʹ 3.7 (3.7– 4.4), tarsal solenidion ω highly curved, knobbed and 7.4 (6.8–7.4), 5 rayed, tarsal empodium em 6.5 (5.6–6.5). Leg II from base of trochanter 40.1 (39.2–40.1); femur 9.3 (8.4–9.3), basiventral femoral seta bv 5.6 (5.6–6.5), genu 4.5 (4.1–4.5), antaxial genual seta 1 ʺ 9.3 (9.3–9.8); tibia 10.2 (9.8–10.2) without paraxial tibial seta 1 ʹ; tarsus 6.5 (5.6– 6.5), paraxial fastigial tarsal setae ft ʹ 19.6 (18.4–19.6), antaxial fastigial tarsal seta ft ʺ absent, paraxial unguinal tarsal seta u ʹ 4.5 (4.1–4.5), tarsal solenidion ω strongly curved, knobbed and 7.4 (6.8–7.4); 5 rayed, tarsal empodium em 6.5 (6.5 – 5.6). Coxae I 18.6 (17.9–18.6) and contiguous; coxal surface ornamented with curve lines; 1 b tubercles and seta present well above the sternal line; seta 1 b 7.4 (7.4–8.4) and 10.1 (9.4–10.1) apart, 1 a tubercles with seta present a little ahead of line across the 2 a tubercles; seta 1 a 13.0 (13.0–14.0) and 6.9 (6.9–7.3) apart; the distance between setae 1 a and 1 b is 8.1 (7.9–8.2); coxa II comparatively smooth except two curve lines along the anterior margin of coxae and 14.9 (14.0– 14.9), seta 2a 39.2 (37.3–39.2) and 18.2 (17.2–18.2) apart. Opisthosoma with 39 (37–39) smooth dorsal annuli and 72 (70–72) ventral annuli; microtubercles rounded and located on first 63 annular lines; last 9 ventral annuli have microstriations, seta c 2 30.8 (28.0– 30.8) present on annulus 14 (13–14), seta d 42.0 (41.0–42.0) on annulus 28 (28–29); seta e 27.0 (26.1 –27.0) on ventral annulus 40 (38–40); seta f 26.1 (25.9–26.1) on ventral annulus 61 (59–62); seta h 1 1.8 (1.2–1.8), seta h 2 39.2 (39.2 – 37.3). Epigynium 9.3 (8.4– 9.3) long, 14.9 (13.8–14.9) wide, smooth except a median sinuate line and semi circular in shape; seta 3a 22.4 (19.6–22.4). MALE: Not observed Type material. Holotype: Female (marked) on slide (no. 1300 / 19 / 2006), India: West Bengal: Malda, Englishbazar, Latitude: 24 ° 50 ʹ 40 ʺ N and Longitude: 87 ° 55 ʹ 50 ʺ E, 23 June, 2006 from Spondias pinnata Kurz (Anacardiaceae), Coll. S. Sarkar. Paratypes: 11 females on slide bearing holotype and 42 females on 5 slides (nos. 1301- 1305 / 85 / 2006); collection data same as in holotype. Relation to host. Light brown, fusiform mites are found as under surface leaf vagrants. Etymology. The specific epithet derived from ‘ Spondias ’ genus of the host plant. Remarks. The new species shows similarities with A. morindae Ghosh & Chakrabarti, 1989 by having ornamented coxae, 5 rayed tarsal empodium, incomplete median line, and 1 b tubercles ahead of anterior coxal approximation, but differs from the latter by having smooth epigynium and in location of scapular tubercles. The new species also resembles A. privae Mohanasundaram, 1980 by incomplete median line on prodorsal shield, ornamented coxae and presence of h 1 setae but differs from the latter by its smooth prodorsal shield margin and dorsal annuli.Published as part of Chakrabarti, Samiran & Sarkar, Sanjay, 2011, Three new species of eriophyoid mites (Acari: Eriophyoidea) infesting fruit yielding plants from India, pp. 28-36 in Zootaxa 2988 on pages 29-31, DOI: 10.5281/zenodo.20372
Financial amplification mechanisms and the Federal Reserve’s supply of liquidity during the crisis
No full textNew York Fed economists Asani Sarkar and Jeffrey Shrader examine the Federal Reserve’s recent liquidity actions in the context of studies on financial amplification mechanisms, whereby an initial financial sector shock triggers substantially larger shocks elsewhere in the sector and in the broader economy. Presented at "Central Bank Liquidity Tools and Perspectives on Regulatory Reform" a conference sponsored by the Federal Reserve Bank of New York, February 19-20, 2009.Federal Reserve System ; Liquidity (Economics) ; Financial crises
Definition, Convention, and Simultaneity: Malament's Result and Its Alleged Refutation by Sarkar and Stachel
No full textThe question whether distant simultaneity (relativized to an inertial frame) has a factual or a conventional status in special relativity has long been disputed and remains in contention even today. At one point it appeared that Malament (1977) had settled the issue by proving that the only non-trivial equivalence relation definable from (temporally symmetric) causal connectability is the standard simultaneity relation. Recently, though, Sarkar and Stachel (1999) claim to have identified a suspect assumption in the proof by defining a non-standard simultaneity relation from causal connectability. I contend that their critique is based on a misunderstanding of the criteria for the definability of a relation, a misunderstanding that Malement's original treatment helped to foster. There are in fact a variety of notions of definability that can be brought to bear. They all, however, require a condition that suffices to secure Malament's result. The non-standard relation Sarkar and Stachel claim to be definable is not so definable, and, I argue, their proposal to modify the notion of ``causal definability'' is misguided. Finally, I address the relevance of Malament's result to the thesis of conventionalism
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis
No full textMutations in the cathepsin D (CTSD) gene cause an aggressive neurodegenerative disease (congenital neuronal ceroid lipofuscinosis) that leads to early death. Recent evidence suggests that presynaptic abnormalities play a major role in the pathogenesis of CTSD deficiencies. To identify the early events that lead to synaptic alterations, we investigated synaptic ultrastructure and function in presymptomatic CTSD knockout (Ctsd) mice. Electron microscopy revealed that there were significantly greater numbers of readily releasable synaptic vesicles present in Ctsd mice than in wild-type control mice as early as postnatal day 16. The size of this synaptic vesicle pool continued to increase with disease progression in the hippocampus and thalamus of the Ctsd mice. Electrophysiology revealed a markedly decreased frequency of miniature excitatory postsynaptic currents (mEPSCs) with no effect on paired-pulse modulation of the evoked excitatory post synaptic potentials in the hippocampus of Ctsd mice. The reduced mEPSCs frequency was observed before the appearance of epilepsy or any morphologic sign of synaptic degeneration. Taken together, these data indicate that CTSD is required for normal synaptic function and that a failure in synaptic trafficking or recycling may bean early and important pathologic mechanism in Ctsd mice; these presynaptic abnormalities may initiate synaptic degeneration in advance of subsequent neuronal loss
Quantum spin pumping at a fractionally quantized magnetization state for a system with competing exchange interactions
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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