4,827 research outputs found
Long-term outcomes of elective surgery for diverticular disease: A call for standardization
No full textTo date, the appropriate management of diverticular disease is still controversial. The American Society of Colon and Rectal Surgeons declared that the decision between conservative or surgical approach should be taken by a case-by-case evaluation. There is still lack of evidence in literature about long-term outcomes after elective sigmoid resection for diverticular disease. Considering the potentially key role of the surgical technique in long-term outcomes, there is the need for surgeons to define strict rules to standardize the surgical technique. Currently there are 5 areas of debate in elective surgery for diverticular disease: laparoscopic versus open approach, the site of the proximal and distal colonic division, the vascular approach and the mobilization of the splenic flexure. The purpose of this paper is to review existing knowledge about technical aspects, which represent how the surgeon is able to affect the long-term results
Totally laparoscopic right colectomy versus laparoscopically assisted right colectomy: a propensity score analysis
No full textIntroduction: The aim of this study is to compare short- and long-term outcomes of totally laparoscopic right colectomy (TLRC) and laparoscopically assisted right colectomy (LARC), using propensity score matching (PSM) analysis. Materials and methods: A retrospective analysis of patients who underwent laparoscopic right colectomy between January 2006 and July 2016 was conducted. PSM analysis was performed to overcome patient selection bias between the two surgical techniques. Results: A total of 116 patients were reviewed. After PSM, 54 patients for the TLRC group and 54 patients for the LARC group were compared. TLRC was associated with shorter post-operative hospital stay (6.81 vs. 4.79 days; p < 0.001) with no difference in 30-day morbidity and mortality. A lower incidence of long-term incisional hernia was observed in the TLRC group (1.9 vs. 21.2%; p = 0.002). TLRC showed better oncological accuracy as demonstrated by a greater number of lymph node achieved (19.21 vs. 15.19; p = 0.001) and higher vascular pedicle length (131.81 vs. 114.76 mm; p = 0.014). Discussion: TLRC is a safe and feasible technique with similar results of LARC in terms of short-term morbidity and mortality. Major advantages related to TLRC are represented by shorter post-operative hospital stay and lower incidence of long-term incisional hernias. Further investigations are needed to assess the oncological outcomes for this technique
ASO Author Reflections: Risk Factors for Anastomotic Leakage in Advanced Ovarian Cancer Surgery-What We Know and Future Perspectives
No full textN/
Prognostic Indicators in Stage IV Surgically Treated Gastric Cancer Patients: A Retrospective Multi-Institutional Study
No full textIntroduction: The role of gastric resection in treating metastatic gastric adenocarcinoma is controversial. In the present study, we reviewed the short- and long-term outcomes of stage IV patients undergoing surgery. Methods: A retrospective review was conducted that assessed patients undergoing elective surgery for incurable gastric carcinoma. Short-and long-term results were evaluated. Results: A total of 122 stage IV gastric cancer patients were assessed. Postoperative mortality was 5.7%, and the overall rate of complications was 35.2%. The overall survival rate at 1 and 3 years was 58 and 19% respectively; the median survival was 14 months. Improved survival was observed for the factors age less than 60 years (p = 0.015), site of metastases (p = 0.022), extended lymph node dissection (p = 0.044), absence of residual disease after surgery (p = 0.001), and administration of adjuvant chemotherapy (p = 0.016). Multivariate analysis showed that residual disease and adjuvant chemotherapy were independent prognostic factors. Conclusions: The results of this study suggest that surgery combined with systemic chemotherapy in selected patients with stage IV gastric cancer can improve survival. (C) 2018 S. Karger AG, Base
Francesco Scorza Barcellona o della passione agiografica
No full textL'autrice traccia, sul filo dei ricordi, il profilo scientifico ed umano di Francesco Scorza Barcellona ed introduce gli studi raccolti nel volume.The author traces, on the thread of memories, the scientific and human profile of Francesco Scorza Barcelona and introduces the studies collected in the book
Delle lodi di don Francesco Medici de' principi di Toscana : orazione /
No full textEngraved t.p. vignette of Medici arms. On recto of 2nd leaf is Callot's full-page engraved port. of Francesco de' Medici, son of Grand Duke Ferdinand I. It is in Lieure's 1st state. The port. also appeared the same year in Alessandro Adimari's Esequie dell' ill.mo & ecc.mo principe don Francesco Medici (Florence : Gio. Donato & Bernardino Giunti); see Lieure. Large woodcut Giunti device on p. [31].Lieure, J. Jacques Callot,Mode of access: Internet.At head of front pastedown is bookplate of Francesco Riccardi de Vernaccia (Florence, ca. 1780; see Gelli, p. 387). Below it is the label of Horatius (Orazio) Landau, with stamped shelfmark 53021. At foot is the bookplate of U. Manganelli, signed with the initials SER. A dedicatory inscription at foot of t.p. has been scratched out.Binding: modern marbled paper, backed in green vellum. Date, author & title writte on spine.Port. trimmed into the image at right margin and foot
Frankenstein
No full text@inproceedings{orsini2015graph,
title={Graph invariant kernels},
author={Orsini, Francesco and Frasconi, Paolo and De Raedt, Luc},
booktitle={IJCAI Proceedings-International Joint Conference on Artificial Intelligence. IJCAI},
year={2015}
Extended or limited lymph node dissection? A gastric cancer surgical dilemma
No full textWe read with great interest the article by Memon and coworkers reporting the outcome of a meta-analysis of randomized controlled trial evaluating the efficacy and drawbacks of limited (D1) versus extended (D2) lymphadenectomy for proven gastric carcinoma. This is a very excellent article; the basic organization of this report is clear and convincing, and the associated conclusions and recommendations are based on a review by investigators with long-standing interest in gastric disorders
Le prime missioni dei Gesuiti in Giappone e la prima ambasceria giapponese in Italia
No full textQuesta tesi di laurea cerca di definire le fasi più importanti della storia delle prime missioni dei Gesuiti in Giappone avvenute nella seconda metà del 16 secolo. Le prime conoscenze più dettagliate sul Giappone si devono al Gesuita Francesco Saverio che fu il fondatore della missione giapponese. In Giappone, Francesco Saverio cercò di allacciare rapporti di reciproca fiducia con le popolazioni locali cercando, seppure in maniera goffa, di adattarsi ai loro costumi. 30 anni dopo la morte di Padre Francesco Saverio, il Visitatore Alessandro Valignano, riprese l'idea di adattamento di padre Francesco Saverio. Il Visitatore durante gli anni del suo mandato si impegnò costantemente per promuovere la fratellanza fra fratelli europei e fratelli giapponesi e capì che se voleva far avvicinare le due culture doveva dimostrare ai giapponesi la raffinatezza e bellezza della cultura europea. Valignano con questa idea formò una delegazione di quattro giapponesi cristiani che avrebbero avuto l'obiettivo di vedere e riferire le bellezze e i costumi dell'Europa
Transanal Total Mesorectal Excision vs Laparoscopic Total Mesolectal Excision in the Treatment of Low and Middle Rectal Cancer: A Propensity Score Matching Analysis.
No full textBACKGROUND:
Transanal total mesorectal excision is a novel and promising technique in the treatment of low and middle rectal cancer.
OBJECTIVE:
This study aimed to compare the safety and feasibility of transanal total mesorectal excision versus laparoscopic total mesorectal excision.
DESIGN:
This was a retrospective study using propensity score matching analysis.
SETTINGS:
This study was conducted in a single high-volume university hospital.
PATIENTS:
Patients with low and middle rectal cancer who underwent total mesorectal excision with curative intent between 2007 and 2017 were recruited.
INTERVENTIONS:
Laparoscopic total mesorectal excision and transanal total mesorectal excision had been performed.
MAIN OUTCOME MEASURES:
Intraoperative, pathological, and 30-day postoperative outcomes were compared between the transanal and laparoscopic groups.
RESULTS:
Overall, 105 patients were selected from the whole sample of 316 patients with rectal cancer. After propensity score matching analysis, 46 patients for each group were compared. Laparoscopic total mesorectal excision was associated with a higher conversion rate to open surgery (19.6% vs 0%, p = 0.002). Transanal total mesorectal excision showed a longer distal resection margin (15 mm vs 25 mm; p < 0.001), and similar results regarding the completeness of mesorectal excision and circumferential resection margin involvement, compared to laparoscopy. There were no statistically significant differences between the 2 groups in terms of postoperative complications.
LIMITATIONS:
The study was limited by its retrospective design and the small size of the sample.
CONCLUSIONS:
Transanal total mesorectal excision is a safe and feasible technique that results in a high-quality rectal cancer resection specimen and favorable 30-day postoperative outcomes
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