1,721,242 research outputs found

    Surgical treatment of recurrences after rectal cancer surgery. Indications and results

    No full text
    The treatment of local recurrences of rectal cancer after surgical therapy is still an open problem. Even if a second look with tumoral excision is not the ideal solution, it represents, whenever feasible the best therapeutic possibility. At the Department of General Surgery and Organ Transplantation, II Medical School, Naples, out of 144 patients treated by potentially curative resection for carcinoma of the rectum between 1983 and 1987, 28 local recurrences (19.4%) were detected. Five of these (17.8%) were associated with liver metastasis. Thirteen patients were reoperated and in 10 cases it was possible to remove the recurrence with a resectability rate of 35% and 50% of reoperations were reported as radical. Operative mortality was 10% and morbidity 30%. Untreated patients or patients operated for decompressive enterostomy only, had a mean survival time of approximately 6 months. All the resected patients, after both radical and palliative operations, were alive after one year. Four of the 5 patients treated by potentially radical resection are alive and disease free at 13, 15 (2 cases) and 18 months; only one patient had a new recurrence at 22 months and died 31 months after the reoperation. After palliative resection, two patients died at 13 and 14 months and 2 patients are alive with recurrent disease at 13 and 17 months. The excision of perineal recurrences is usually not technically demanding whereas for pelvic recurrences the role of Hartmann operation should be revealed. Although a concrete outlook of cure is seldom achieved after radical resection, an acceptable long term survival is nearly always possible. Palliative operations results in longer survival as compared with non surgical treatments, with the substantial advantage of a better quality of life. Even though this study reports on a small number of patients an aggressive surgical approach seems, to date, justified because of the inefficacy of alternative forms of treatment

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Introduzione. Università, città, student*.

    No full text
    Il capitolo mette in relazione le dinamiche di sviluppo degli atenei, nel contesto italiano, in relazione alle dinamiche di sviluppo urbano e alla presenza di una popolazione studentesca universitaria sempre più caratterizzata da numeri consistenti di studenti fuori sede o internazionali
    corecore