50 research outputs found
évaluation des connaissances des étudiants de la faculté de médecine d'odontostomatologie, de la faculté de pharmacie sur les moyens de contraception
No full textNotre étude transversale s'est déroulée à Bamako en juillet 2017 au décembre 2018. L'objectif consistait à analyser les connaissances et attitudes des étudiants de la FMOS face aux moyens de contraception. La majorité des étudiants soit 77,4 p.100 (41/53) lors du prétest déclaraient avoir une connaissance insuffisante sur les méthodes de contraceptions et parmi eux 85,7 p.100 (30/35) pour un p inférieur à 10-3(khi2) lors du prétest ne savaient rien comme connaissance sur l'efficacité du préservatif. L'absence de besoin et de religion était la principale raison de non-utilisation de certains étudiants alors que la majorité vivait au village du point-G. La grande majorité des jeunes étaient sexuellement actifs, la tranche d'âge moyen au premier rapport sexuel était 21 à 2
Open Science in Public Health in Africa: An Exploratory Investigation of the Barriers and Solutions Dataset
No full textDataset for submitted publicatio
Écrire l’Islam en bambara. Lieux, réseaux et enjeux de l’entreprise d’al-Hâjj Modibo Diarra
No full textAl-Hâjj Modibo Diarra, nouvel acteur du paysage religieux malien, publie régulièrement, depuis 1987, des ouvrages de vulgarisation islamique en langue bambara, comportant aussi des traductions de l’arabe (extraits coraniques inclus). Son initiative relie les langues, les formes de communication orales et écrites, les savoirs et les réseaux dans l’islam ouest-africain. Les librairies bamakoises les distribuent en même temps que le village de l’auteur demeure le centre de sa production. Le milieu des librairies urbaines sert de relais à un phénomène qui reste pourtant essentiellement rural, tant par ses origines que par sa destination. Le parcours biographique de l’auteur/traducteur est à cet égard emblématique. Cette production imprimée islamique en bambara reconfigure les pratiques et les savoirs islamiques.Al-Hajj Modibo Diarra, a new actor of the Malian religious landscape, since 1987 has been publishing several booklets popularizing Islamic doctrine in Bambara language. These also contain translations from Arabic (including excerpts from the Qur’an). This initiative ties relationships between languages, oral and written forms of communication, genres of knowledge, and networks in West African, especially Malian, Islam. The Islamic bookshops in Bamako serve as places of publication and circulation while the village where the writer lives is including the actual writing of these works. The milieu of urban Islamic bookshops proves to work as a link for a phenomenon which remains, though, fundamentally rural, both in its origins and in its target. However, this very phenomenon must also be understood as a result of the growing integration of a milieu so far considered impervious into different kinds of networks that go beyond a merely local setting: the author/translator’s biography considered here is a case in point. The impact of this Bambara Islamic literature is discussed, alongside its implications upon local representations and reconfigurations of Islamic knowledge
A contemporary Malian Shaykh: Al-Hajj Shaykh Sidy Modibo Kane Diallo, the religious leader of Dilly
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Recent studies have pointed to the relationships between marabouts and power in West Africa. The present author argues that these studies should be broadened to include marabouts not necessarily linked directly to particular regimes, but whose reputations and widespread popularity put them in a complex relationship to power. He presents a biographical note on the most influential marabouts in present-day Mali, Sidy Modibo Kane Diallo, born in 1925 in the town of Dilly, in the cercle of Nara which was then the French Sudan. In 1974 he became the official 'khalifa' of the Kane Diallo family. Today his reputation rests in large part on his efforts to spread Islam in Mali, particularly among the Bambara of Beledugu and Kaarta. Other factors which have served to enhance Sidy's reputation include the yearly 'ziyara' in Dilly and his role as a 'khalifa' of the Quadiriyya brotherhood. His circulation within Mali has been subject to authorization by the Malian State. Wherever he travels, he is received with great fanfare not only by villagers but also by representatives of the State who shower him with gifts and solicit him for blessings. The State cannot fail to recognize the potential benefits of its association with Sidy, and at times seems to act to exploit his influence, although he is not closely linked to the Traor‚ regime. Notes, refASC – Publicaties niet-programma gebonde
The independent African American labor movement in the formation of the American state and the consolidation of capitalist class power, 1993
No full textThis is a theoretical analysis of the Independent African American Labor Movement and its influence upon the American state. Two of the early periods in American political history are considered. The central theme of the analysis is the role of slave labor in the context of the plantation system in the formation of the state and in the eventual consolidation of the class power of American capitalists
Synthetic SARS-CoV-2 (2019-nCoV), MERS-CoV and SARSr-CoV vaccine : A comparative computational analysis to propose candidate epitopes
No full textBackground: Coronaviruses are normally specific to an animal taxon as host, mammals or birds depending on their species; however, these viruses can sometimes change host as a result of mutation. The HCoV-229E is one of six human coronaviruses that include HCoV-NL63, HCoV-OC43, HCoV-HKU1, MERS-CoV and SARSr-CoV (SARSr-CoV-1 and SARS-CoV2) and is distributed globally. MERS-CoV and SARS-CoV-2 could persist on inanimate surface like (metal, glass or plastic for up to nine days) (Huang, C.-L, 2020). Preventive measures and drug treatment with hydrochloroquine are useful, but a good effective vaccine may be needed to stop propagation of the covid-19 pandemic. The aim of our study was to identifiy vaccine candidate epitopes by bioinformatics approaches.
Materials and Method: The complete genomic sequences of SARS-CoV-2 were obtained from 2019 Novel Coronavirus Resource (2019nCoVR) and two databases, including the National Center for Biotechnology Information (NCBI) Global Initiative on Sharing All Influenza Data (GISAID) and TAURAU/T-bio-infoserver for online bioinformatics. we will provide a brief review of viral origin, compare the sequencing data for conserved region identification, his commonest protein domain( target binding site) and consensus motif design for an potential candidate molecule (epitope) prurposition for treatment strategies for the newly identified 2019-nCoV , SARSr-CoV strain and MERS-CoV.
Results: Interestingly, sequence comparison between SARS-CoV-2 and another strain revealed that the residues present in the receptor-interacting motive are highly conserved with 70 % identity. we funded five important amino acids ( L455, Y473, N479, F486, Q493) on the receptor binding domain from spike proteins responsible of contact between virus and horst . In the SARS-CoV_ RBD are present residues (D480, and T487) that allowed the interspecies infection. However, in SARS-CoV-2, slight modification of some residues could improve the interaction with the human cellular receptor: L455, F486, Q493, and N501. In SARS-CoV, two main residues (479 and 487) have been associated to the recognition of the human ACE2 receptor. In the SARS-CoV-2, the residues corresponding to N479 correspond to Q493 and T487 to N501. These changes in the SARS-CoV-2 represent energetically favorable changes for the interaction with the receptor. we identified the sequences of amino acids that are well conserved across many coronaviruses including 2019nCoV and other strains, the motif KRSFIEDLLFNKVTLADAGF was found to be particularly well-conserved in this study and corresponds to the region around one of the known cleavage sites of the SARS virus that are believed to be required for virus activation for cell entry. This sequence motif and surrounding variations formed the basis for proposing a specific synthetic vaccine epitope this finding can make related likely rigid small molecule candidates and binding targets.
Conclusion: This study provides information and opportunities for biological confirmation. The work can nevertheless be described in bioinformatics terms, and easily replicated by others, although new data and research on Covid-19 are emerging and evolving at an explosive rythm
Solidarity-based Financing of Health Care Access for the Poor Patients at the University Hospital Point G, Bamako, Mali
No full textIntroduction: Almost half of the world\u27s populations do not have access to basic health care. This exclusion mainly affects people living in rural areas, who are nevertheless the most susceptible to diseases. The Medical Assistance Plan allows a marked improvement in access to healthcare by poor patients. It eliminates out of pocket healthcare cost, which normally prevents most of them from accessing health care. Materials and methods: This study was aimed to investigate the accessibility to healthcare for poor patients at the University Hospital Point G. We conducted a 12-month descriptive cross-sectional study from March 2018 to April 2019. Data entry and analysis were performed using SPSS version 21.0. Results: Our study participants we interviewed were aged 30-44 years old in 30.7%, female in 60.7%, and housewives in 46.7%. Our interviewees consulted for consulted for chronic diseases in 79.3%, had no monthly income in 78.7% and obtained the healthcare benefits at no cost to them in 60.7%. The prescriptions costed between 5,000 and 15,000 FCFA in 51.1%, 20252 FCFA on average with a standard deviation of 1340 FCFA. In sum, 59 out of our 150 patients who were eligible for free healthcare had to pay for a contribution either a subsidized cost in 84.7% or a partial purchase in in 15.3%. Conclusion: The main barriers to healthcare were the chronicity of their diseases and the expensiveness of the healthcare due the level of poverty in the country.
Keywords: Solidarity financing, Access to healthcare, poor, CHU Point G / Mal
