24 research outputs found
ACSA: Conference book: Design Studies
No full textIn recent years, the Faculty of Architecture, Housing, Urban Design and Planning has been undergoing large changes in the training and research program mes. These changes followon from the signals received from professional practice, but above all from the desire of staff and students to design programma and organization in such a way that they play along with new developments in the field of architecture in an international context. As in 1992 the University of Technology at Delft is celebrating its 150 years in existence, and ACSA was planning to organise a congress in collaboration with a European university, it was decided to organise this congress as a collaboration between ACSA and the Faculty in Delft. After careful consideration it was also decided to place the emphasis in this congress on research in relation to architectural education. We are aware that the time is long gone when the designing of buildings, cities and landscapes could develop without proper reflection from designing research. Ends and means must be weil attuned to each other, as weil as the various aspects of function, structure and form, and of pattern and process. The professional field is renewing itself through the development of new materials and construction techniques, new aids such as the computer, and new problems such as the growth of eities and mobility, environmental protection and energy saving, and the confrontation of rich and poor. It leads to new tasks for the architect and the accompanying research must be newly formulated. Partly as a consequence of these problems, the congress is set up along 3 main lines: designing research in the field of Architecture and Urban Planning; designing research in the field of Building Technology; architectural research in connection with computer-backed designing. For the Faculty of Architecture, Housing, Urban Design and Planning these themes are elements of a new research programma which was started up last year. They form a foundation for the main subject of Architecture, Housing, Urban Design and Building Technology. Our faculty therefore regards this congress as a welcome opportunity to achieve a better foundation and execution of design research. And in this way also, a more intensive cooperation with European and American Architecture faculties.UrbanismArchitectur
Nurturing the Mind through Environmental Stimuli
No full textThe dictionary defines nurture as "the act or process of raising or promoting the development of; training; rearing; upbringing" . Nurture also means "to feed" and "to nourish" (Webster's Unabridged Dictionary, 1977 edition) . Nurturing the mind involves a proper balance of internal and external stimuli. The nurturing of crops also has internal and external stimuli and has a number of interesting parallels to the nurturing of students in the architectural design studio. The author will examine these parallels in order to
increase the reader's awareness of successful nurturing methods and techniques on the part of the studio instructor. The characteristics of a supportive "nurturing" environment are discussed in the paper through a series of analogies to the planting and raising of crops. It is the hoped that an increased understanding of the nature of nurturing will aid design educators in the classroom.This presentation is published as Osterberg, A.E., Nurturing the Mind Through Environmental Stimuli, presented at ACSA Western Regional Meeting, held at Colifornia State Polytechnic Univeristy Pomona, A October 1988. https://www.acsa-arch.org/. Posted with permission
ACSA: Visitors Guide: Randstad Holland
No full textThis publication is intended for American architects, who in the context of the Delft ACSA Conference 1992 would like to catch a glimpse of Dutch architecture. But at the same time it is a good guide for everyone who wants a one-day introduction to the urban agglomaration of the Netherlands. The Randstad is an attenuated urban area which stretch es from Utrecht to Rotterdam, incorporating Het Gooi, Amsterdam, Haarlem, Leiden, Den Haag, and Delft. In contrast to conurbations like London or Paris, the Randstad has no single centre. Instead, this 'ring city' winds its way round the meadows of its Green Heart. With its principal cities, harbours, and Schiphol airport, the Randstad is the economie centre of the Netherlands. At present the Randstad has approximately 2,5 million dwellings for a population of roughly 6 million people. As the area expands over the next 25 years, the population is expected to increase to 7 million, an increase of 17 %, while the number of dwellings are expected to increase by 40 %. The Netherlands comprises an area of roughly 160 by 240 kilometres. If you subdivide the Netherlands into six squares, each 80 kilometres square, three squares long and two squares wide, the Randstad, together with its Green Heart, occupies the middle square in the western row. Of course, dividing the country into the Randstad and the remainder of the Netherlands is not the only available manner of subdivision. It is also possible to split the Netherlands into a Northern Wing and a Southern Wing. This configuration yields a different picture: no longer one of an urban agglomeration in the middle of the country, but rather two extended urban concentrations extending across the breadth of the Netherlands and comprising both the coastal areas and the hinterland. Nonetheless, the Dutch government considers the Randstad configuration to be the more adequate and the more fruitful concept for planning decisions from the viewpoint of development on an international scale. The excursion takes you through various typically Dutch landscapes such as dunes and polders. The buildings which are visited illustrate mainly the Dutch architecture of this century.ArchitectureArchitectur
Social media marketing y el posicionamiento de la municipalidad provincial de Paucartambo frente a sus pobladores, Cusco 2024
No full textEl social media marketing y el posicionamiento son esenciales para que los municipios promuevan sus servicios y fortalezcan su vínculo con la población. Esta investigación analizó la asociación entre ambas variables en la Municipalidad Provincial de Paucartambo, Cusco, durante el 2024. Se aplicó un enfoque cuantitativo, con diseño aplicado, no experimental y transversal. La muestra incluyó 381 usuarios de redes sociales, seleccionados mediante muestreo aleatorio simple. Se utilizó un cuestionario con escala Likert. El coeficiente de Spearman reveló una correlación positiva alta (rho = .852; p = .000), indicando un impacto significativo del marketing digital. En conclusión, el marketing en plataformas digitales es esencial para fortalecer la imagen institucional, ampliar su alcance y mejorar la visibilidad de la gestión pública.TarapotoMarketing y Negocios InternacionalesMarketin
Automating cyber security advisories: Supervised machine learning for automated decision making
No full textThere is an everlasting struggle for organisations to remediate vulnerabilities in IT systems before being the victim of an exploitation. Organisations try to reduce this struggle by turning to specialized cyber organisations, which use their expertise to recommend resolving a subset of vulnerabilities. Unfortunately, the process of recommending a selection of vulnerabilities is primarily done manually. Manual labour is time consuming and requires skilled personnel. Automating cyber advisories reduces both these problems.We introduce ACSA, a process designed for the Automation of Cyber Security Advisories. ACSA creates a dataset that can be used by advisory publishers to automate their publications with minimal effort. The dataset contains around 90,000 advisories which are filtered by a machine learning model to the set published by the organisation. We applied the ACSA process and dataset to both the Dutch and Canadian NCSC and found that on average we can already automate the majority of advisories. This constitutes a significant workload reduction in comparison to the situation prior to the automation. Even better results are observed when looking at the performance of ACSA on specific vendors. For some vendors we are able to automate more than 90% of the advisories while creating minimal false positives.Computer Scienc
Consequences of Proportional Systems in Architecture
No full textThe system of architecture inscribed by Vitruvius in De Architectura and famously drawn by Leonardo da Vinci in 1490, as well as Cesar Cesariano after him in 1521, has provided modern architecture and art historians with argumentation for placing the architectural object at the centre of a system of relations between symmetry, geometry and proportion. When one looks at the last 100 years, this system of relations can be seen to have regulated, in varying ways, architectural design methodology since its ‘rediscovery’ and re-inscription into architectural discourse in the middle of the 20th century by the architecture and art historians, such as Rudolf Wittkower in his book Architectural Principles in the Age of Humanism (1949) and the essays by Colin Rowe titled “The Mathematics of the Ideal Villa” (Architectural Review, 1947) and “Mannerism and Modernism” (Architectural Review, 1950). This paper, which is a work-in-progress excerpt from PhD research by the author, argues that these works established a dominant fiction(1) in the discipline of architecture, or a way for architects to perceive and interpret the built environment. However, with advances in the technology of production in the last twenty years, and, in parallel, the development of contemporary discourses of computation and digital design in relationship to the natural sciences, this system can be questioned and the dialogue between forms of production, systems of proportion and architecture re-opened.1 – The term ‘dominant fiction’ was outlined in Silverman, Kaja. Male Subjectivities at the Margin, Psychology Press (1992)
Formation of motile assembly of microtubules driven by kinesins
No full textMicrotubule (MT) and kinesin are rail and motor proteins that are involved in various moving events of eukaryotic cells in natural systems. In vitro, the sliding motion of microtubules (rail) can be reproduced on a kinesin (motor protein)-coated surface coupled with adenosine triphosphate (ATP) hydrolysis, which is called a "motility assay". Based on this technique, a method was recently established to form MT assemblies by an active self-organization (AcSA) process, in which MTs are crosslinked during a sliding motion on a kinesin-coated surface. Streptavidin (ST) was employed as glue to crosslink biotin-labeled MTs. Various shapes, sizes, and motilities were formed with the AcSA MT assemblies, depending on the initial conditions. In this paper, we briefly review our recent work on the formation of MT assemblies on a kinesin-coated surface
Auto-configuration of shared network-layer address in cluster-based wireless sensor network
No full textNetwork-layer address is used to identify sensor nodes in wireless sensor networks (WSNs). Since a WSN might be composed of a huge number of sensor nodes, it is difficult to assign an address to each node manually. In this paper we propose a novel auto-configuration algorithm ACSA, which assigns an address to a geographical area instead of an individual sensor node. This addressing scheme is based on the fact that there is no need to exchange packets between arbitrary nodes pair. By reducing the address size, ACSA is more energy-efficient and scalable. This new address assignment scheme is also adaptive to network change. Experiments using NS-2 have shown that ACSA achieves better performance and energy efficiency in WSNs.Automation & Control SystemsComputer Science, CyberneticsEngineering, Electrical & ElectronicTelecommunicationsCPCI-S(ISTP)
Biomechanical implications of skeletal muscle hypertrophy and atrophy: a musculoskeletal model
No full textabstract: Muscle hypertrophy and atrophy occur frequently as a result of mechanical loading or unloading, with implications for clinical, general, and athletic populations. The effects of muscle hypertrophy and atrophy on force production and joint moments have been previously described. However, there is a paucity of research showing how hypertrophy and atrophy may affect moment arm (MA) lengths. The purpose of this model was to describe the mathematical relationship between the anatomical cross-sectional area (ACSA) of a muscle and its MA length. In the model, the ACSAs of the biceps brachii and brachialis were altered to hypertrophy up to twice their original size and to atrophy to one-half of their original size. The change in MA length was found to be proportional to the arcsine of the square root of the change in ACSA. This change in MA length may be a small but important contributor to strength, especially in sports that require large joint moments at slow joint angular velocities, such as powerlifting. The paradoxical implications of the increase in MA are discussed, as physiological factors influencing muscle contraction velocity appear to favor a smaller MA length for high velocity movements but a larger muscle MA length for low velocity, high force movements.The final version of this article, as published in PeerJ, can be viewed online at: https://peerj.com/articles/1462
Author Correction: Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection
No full textThe original version of this Article contained a factual error within the discussion section, which incorrectly stated that SARS-CoV-2 expresses a hemagglutinin esterase. This has been corrected in the PDF and HTML version of the Article by the removal of the corresponding text. The deleted text is reproduced below: Besides the spike glycoprotein, coronaviruses, including SARS-CoV-2, express at their surface the hemagglutinin esterase (HE) that often contains an active lectin domain that mediates glycan binding in several other viruses. However, the HE lectin domains of HCoV-OC43 and HCoV-HKU1 lost their glycan binding capacity due to mutations and deletion during adaptation to human host62. Our result also suggests that HE might not be directly involved in 9-AcSA binding, as binding kinetics to AcSA is similar on purified S1 and at the virion level. However, as their esterase activity is maintained, HE could be involved in the deacetylation during release of viral progeny from the host cell surface and possibly also for breaking decoy interactions of the S protein with O-AcSA carrying mucins63.</p
