1,720,954 research outputs found
Pristane plus v-abl/myc induced lymphoma and plasmacytoma development in STS/A mice
Get PDF The STS/A (STS) mouse is a highly resistant strain for radiation-induced hematopoietic and mammary gland neoplasms while BALB/cHeA mouse is susceptible. The BALB/c mouse strain is also sensitive to peritoneal plasmacytoma (PCT) induction by a variety of agents, including plastic implants, paraffin oils, pristane and pristane plus v-abl/myc, with different latency periods, incidences and effectiveness.
The objective of this study was to investigate the susceptibility of the STS mouse to pristane plus v-abl/myc induced plasmacytomagenesis. Materials and methods: Ten mice from a control group were intraperitoneally injected with pristane only and the other ten mice were injected with pristane followed by v-abl/myc. All mice were investigated routinely for ascitis and tumor formation up to 100 days. Histologic slides were prepared from harvested tumor samples as well as CD138 immunofluorescence staining for plasma cells detection. Results: Four of ten mice in pristane plus v-abl/myc group developed ascites and showed evidence of lymphoid malignancies. Three of the ten mice had mixed tumors (lymphoma and PCT) and one of ten had lymphoma. None of the control STS mice developed a tumor. The average latency period of tumor development in STS mice was 90 days which was longer than pristane plus v-abl/myc plasmacytomagenesis in BALB/c and congenics. The relative risk of tumor resistance of a control group compared to the test group was 1.67 (95% confidence interval (CI): 1.005-2.765). Conclusion: The STS mice were not completely tolerate to pristane plus v-abl/myc plasmacytoma induction but an average latency period of tumor formation was longer than the BALB/c and congenics mouse strain. This extended period indicated some resistances in the STS genetic background.
Keywords: lymphoma, plasmacytoma, mouse tumor induction, mouse chromosome 11, v-abl/my
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Prevalence and Characteristics of Dental Anomalies in Pediatric Patients at a Dental Hospital in Thailand
No full text This retrospective study was performed by collecting data from dental records of 385 pediatric patients who had a complete dental examination and treatment planning at Dental Hospital in Phitsanulok, Thailand, during the period of January 1, 2014 – December 31, 2017. The objective of this study is to evaluate the prevalence and characteristics of the most frequently found dental anomalies. The results show that the prevalence of dental anomaly in pediatric patients is 13.25%. The most prevalent anomalies are congenital missing teeth (34.38%), supernumerary teeth (20.31%), embedded teeth (9.38%), enamel hypoplasia (7.81%), and others (1.56%-6.25%). A chi-square test revealed a significant relationship between child age and dental anomaly (P=0.001), in which dental anomaly prevalence is higher in children age 6-12 than in children age 0-5. No significant relationship existed between dental anomaly and sex, systemic disease, or physiological/psychological disorder (P>0.05). The most common disorder associated with dental anomaly was “cleft lip with cleft palate”, and the most common anomaly associated with that disorder was congenital missing permanent anterior maxillary teeth.
Keywords: dental anomalies, pediatric, prevalence, congenital missing teeth, supernumerary teet
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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