1,785,555 research outputs found
Invited Lecture by Subhrajit Saha
No full textInvited lecture given by Subhrajit Saha at Agronómico Tropical de Investigación y Enseñanz
"Our Trees Are Dying": KIT Forest Researcher Somidh Saha about Karlsruhe Hardtwald
No full textDer Klimawandel bringt immer häufigere Trockenheit und Dürre mit sich. Damit steigt die Waldbrandgefahr. Der Forestwissenschaftler Dr. Somidh Saha vom Institut für Technikfolgenabschätzung und Systemanalyse (ITAS) des KIT plädiert für mehr Forschung und mehr Mut zum Experiment
DNA and RNA Cleavage Complexes and Repair Pathway for Topoisomerase 3B (TOP3B) RNA- and DNA-Protein Crosslinks. Saha et al.
No full textRaw data related to article "DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B
RNA- and DNA-Protein Crosslinks
Testing Equivalence to Design Polynomials
Get PDFAn n-variate polynomial g of degree d is a (n,d,t) design polynomial if the degree of the gcd of every pair of monomials of g is at most t-1. The power symmetric polynomial PSym_{n,d} : = ∑_{i = 1}ⁿ x^d_i and the sum-product polynomial SP_{s,d} : = ∑_{i = 1}^{s}∏_{j = 1}^{d} x_{i,j} are instances of design polynomials for t = 1. Another example is the Nisan-Wigderson design polynomial NW, which has been used extensively to prove various arithmetic circuit lower bounds. Given black-box access to an n-variate, degree-d polynomial f() ∈ [], how fast can we check if there exist an A ∈ GL(n, ) and a ∈ ⁿ such that f(A+) is a (n,d,t) design polynomial? We call this problem "testing equivalence to design polynomials", or alternatively, "equivalence testing for design polynomials".
In this work, we present a randomized algorithm that finds (A, ) such that f(A+) is a (n,d,t) design polynomial, if such A and exist, provided t ≤ d/3. The algorithm runs in (nd)^O(t) time and works over any sufficiently large of characteristic 0 or > d. As applications of this test, we show two results - one is structural and the other is algorithmic. The structural result establishes a polynomial-time equivalence between the graph isomorphism problem and the polynomial equivalence problem for design polynomials. The algorithmic result implies that Patarin’s scheme (EUROCRYPT 1996) can be broken in quasi-polynomial time if a random sparse polynomial is used in the key generation phase.
We also give an efficient learning algorithm for n-variate random affine projections of multilinear degree-d design polynomials, provided n ≥ d⁴. If one obtains an analogous result under the weaker assumption "n ≥ d^ε, for any ε > 0", then the NW family is not VNP-complete unless there is a VNP-complete family whose random affine projections are learnable. It is not known if random affine projections of the permanent are learnable.
The above algorithms are obtained by using the vector space decomposition framework, introduced by Kayal and Saha (STOC 2019) and Garg, Kayal and Saha (FOCS 2020), for learning non-degenerate arithmetic circuits. A key technical difference between the analysis in the papers by Garg, Kayal and Saha (FOCS 2020) and Bhargava, Garg, Kayal and Saha (RANDOM 2022) and the analysis here is that a certain adjoint algebra, which turned out to be trivial (i.e., diagonalizable) in prior works, is non-trivial in our case. However, we show that the adjoint arising here is triangularizable which then helps in carrying out the vector space decomposition step
Scolytoplatypus lopchuensis Maiti & Saha
No full text11. Scolytoplatypus lopchuensis Maiti & Saha * Scolytoplatypus lopchuensis Maiti & Saha, 2009: 90. Thai distribution: N: Chiang Mai. New to Thailand. New record: Chiang Mai, Doi Inthanon NP, Checkpoint 2, 18° 31.55' N, 98° 29.94' E, 1700 m, MT, 8–15.v.2007 (Y. Areeluck) (1). Other distribution: India (W. Bengal). (2) Taxonomy: In their description of the male, Maiti and Saha (2009) fail to mention the prosternum, which is a valuable taxonomic character in Scolytoplatypus (Beaver & Gebhardt 2006). It is broadly flattened posteriorly, but tapers anteriorly to a sharp point which is more strongly sclerotised. The tapering part bears long, backwardly pointing hairs, and at the tip on each side, a small tuft of short, forwardly pointing hairs. Maiti and Saha (2009) do not mention also the extremely long tufts of hairs on the anterior coxae. These are longer than in any other species of Scolytoplatypus known to us, the longest hairs extending two-thirds of the body length. Biology: Maiti and Saha (2009) list three host species in three different families (Lauraceae, Rutaceae, Symplocaceae). Given the localities listed by Maiti & Saha (2009), and above, probably a montane species. Illustrations: D (Maiti & Saha 2009).Published as part of Beaver, R. A., Sittichaya, W. & Liu, L-Y., 2014, A Synopsis of the Scolytine Ambrosia Beetles of Thailand (Coleoptera: Curculionidae: Scolytinae), pp. 1-82 in Zootaxa 3875 (1) on pages 17-18, DOI: 10.11646/zootaxa.3875.1.1, http://zenodo.org/record/513058
EVALUATION OF HISTONE DEACETYLASE INHIBITOR EFFECTS ON THYROID CANCER
No full textAbstract
Histone deacetylases (HDACs) play a crucial role in the proper regulation of cellular functions through their connection with chromatin and transcriptional regulation. Alterations in HDAC activity have been reported in several types of cancer encouraging development of HDAC inhibitors (HDACis) for cancer treatment. The antitumor activity of HDACi has been demonstrated, in clinical trials, in both solid and non solid neoplasias at doses well tolerated by patients. However, the molecular basis for their tumor selectivity is unknown. Anaplastic thyroid carcinoma (ATC) is one of the most aggressive malignancies, having a poor prognosis and being refractory to conventional chemo- and radiotherapy. To the aim to find an innovative therapy for the treatment of ATCs, we studied the effects of two potent HDACis, SAHA and MS-275, on rat thyroid cell lines transformed by the v-ras-Ki oncogene which is frequently mutated in ATCs. We show that: i) HDAC 1 and HDAC 2 are overexpressed in anaplastic thyroid carcinomas compared to normal thyroid; ii) SAHA and MS-275 induce apoptosis selectively in completely transformed rat thyroid cells; iii) TNF-related apoptosis-inducing ligand (TRAIL) is the main mediator of cell death induced by SAHA; iv) SAHA stabilize TRAIL protein by affecting its proteasome-mediated degradation
SAHA READY RECKONER - A NEW PRACTICAL APPROACH FOR DIRECT ASSESSMENT OF COCOON YIELD
No full textQuality silkworm seed play a vital role for production of better cocoon yield. Irrespective of fecundity. uniform number of eggs should be fixed for 100 dfls while assessing performance of silkworm breed or hybrid. Though the yield is directly proportional to fecundity. hatching percent. ERR percent and single cocoon weight, standard norms should be fixed for determination of cocoon yield/100dfis. The Saha Ready Reckoner described here may be helpful in direct assessment of cocoon yield at laboratory and field level easily
Saha Türklerinin bilmeceleri
Get PDFSahalar zengin bir halk edebiyatına sahiptir. Bilmeceler de Saha edebiyatında önemli bir yer teşkil eder ve halk arasında yaygın bir kullanıma sahiptir. Türkiye’de Saha bilmeceleri üzerine müstakil bir çalışma yapılmamıştır. Buçalışmamızda daha önce Türkiye’de yayınlanmış Saha bilmecelerle birlikte ilk defa tarafımızdan Saha Türkçesinden
Türkiye Türkçesine aktarılan bilmeceler konuları bakımından sınıflandırılmıştır. Ayrıca bilmeceler şekil ve içerikleri bakımından değerlendirilmiştir.The Sakhas have a rich folk literature. The Riddles also have an important place in Sakha literature and widespreaduse among the people. There has not been a specific study on Sakha riddles in Turkey before. Along with thosepreviously published in Turkey, the riddles, classified according to topics, have been transferred to Turkish in Turkeyfrom Sakha Turkish for the first time by us. Riddles are evaluated in terms of form and content
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