13 research outputs found
Internet Addiction: A Comparative Study Among Children in the State of Madhya Pradesh and Chhattisgarh
No full textBackground: The Internet is the leading and most resourceful foundation of information in the world today. Internet has become a part of many peoples, mostly young in everyday routine. There has been an explosive growth in the use of internet not only in India, but also worldwide in the last decade. Currently internet has become an important tool for education, entertainment and communication. Increased internet usage may lead to point of addiction, adverseintellectual, habituation, mental complications, corporal disturbance and social effects.India now has the world’s second-largest internet user population, with approximately, 460 million Internet users in 2017.This paper explores the research on how children and youth of depend on all type of gaining the knowledge and communication ininternet and then become addicts. Aim: The aim was study to find out the internet addiction among children in the state of Madhya Pradesh and Chhattisgarh, India. Method: A comparative study was conducted among children (n=70) of two district between Sagar (Madhya Pradesh) and Surajpur (Chhattisgarh), India, to assess the pattern of internet usage. Researcher have employed semi-structured interview schedule to collect primary data it’s includes like socio-economic profiles of the respondent with Young’s Internet Addiction Test Scale (IAT) and their age between 7-18 years old.The study time duration of January – May 2015 and data was analyzed using SPSS version 21.0. Result:Out of 70 participants 50% of the both districts. 42 (60%) were Males and 28 (40%) Females. Majority of 42 (60%) were 15-<18 years old and 67 (97.5%) were students. 8 (21%) of the respondents were spent their time on internet in cyber cafe for 3-4 hours per day.In this study, 25 (37.9%) Father, 9 (13.2%) Mother, 28 (57%) Brothers and 5 (29.4%) Sisters of the respondents were using internet. According to Young’s 20-item scale were 9 (12.85%) respondents (score >79) severe addicts of internet, and most important these all are belonging from Sagar. 39 (55.72%) respondents as moderate (score 50-79) and 22 (31.43%) respondents were mild and safe (score <49). Keywords: interned addiction, internet usage, adverse effects, internet addiction disorde
Infinite Coffee Cup
No full textImagine you go to your favorite cafe house or a restaurant and the system recognizes your presence and alerts the waiter and caters to your favorite beverage you longed for the day. The main motivation to Infinite Coffee Cup is to detect the presence of a person and dynamically and non-Invasively estimate the amount of coffee in a circular cup on the table. One of the more popular devices used is Microsoft Kinect, which has cameras that capture both RGB and Depth data. Kinect is a low cost sensing device which provides two streams of images, 8 bit 3 channel RGB image and 11 bit single channel depth image. The system is fixed at the roof facing downwards and it takes a top view of the cup placed on the table. We use ``libfreenect'' 1] drivers which is an open source project, to stream data from kinect. We employ various image processing algorithms using OpenCV (Open Source Computer Vision) which is a library of programming functions for real time computer vision. The algorithms are used to manipulate the data from kinect to, - Detect the circular coffee cups in the RGB image. - Overlay and correlate the depth values of cups in the depth image to get the height and amount of coffee in the cup
Nutrient Recovery and Recycling from Human Urine: A Circular Perspective on Sanitation and Food Security
No full textAbstractClosed-loop nutrient cycling is a simple, persuasive and elegant approach to realize efficient natural resource management, improved human well-being and long-term food security. In the spirit of sustainable sanitation through nutrient cycling, this study proposes a new pathway to realize resource recovery from anthropogenic waste fractions by the application of physico-chemical separation processes. Microwave Activated Carbon (MAC) prepared from coconut shells (agro-waste) were immobilized on etched glass bead supports and utilized within a continuous flow packed-bed column. Physical adsorption experiments were performed by passing human urine through the column to strip and recover more than 80% of the intrinsic urea. Backwashing of the column was performed to demonstrate the ease of urea-N desorption, reusability of MAC over multiple cycles and the reversible nature of the process. Further nutrient recovery was realized by dephosphatizing the column overflow with MgO to allow phosphate precipitation (>90%) as struvite. Sorption kinetics, behaviour and influence of process parameters were studied by testing the experimental data against Yoon-Nelson, Thomas and Adams-Bohart models. The column adsorption was also numerically optimized using Response Surface Methodology to determine the optimal parameters as: sorbate flow rate – 8.5 L.h-1, urea concentration – 100%, support size – 1 cm and consequently, column capacity of 21.58 g. Nutrient recovery, concentration and recycling from diverted human urine can be seen as a synergistic and circular solution to the issues of sanitation, hygiene, water, and food security
Avaliação clínica a longo prazo de pacientes obesos submetidos ao tratamento cirúrgico bariátrico no Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC)
No full textTrabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Clinica Medica
Mathematical and Computational Modelling of Ribosomal Movement and Protein Synthesis: an overview
No full textTranslation or protein synthesis consists of a complex system of chemical reactions, which ultimately result in decoding of the mRNA and the production of a protein. The complexity of this reaction system makes it difficult to quantitatively connect its input parameters (such as translation factor or ribosome concentrations, codon composition of the mRNA, or energy availability) to output parameters (such as protein synthesis rates or ribosome densities on mRNAs). Mathematical and computational models of translation have now been used for nearly five decades to investigate translation, and to shed light on the relationship between the different reactions in the system. This review gives an overview over the principal approaches used in the modelling efforts, and summarises some of the major findings that were made
Assessing the influence of R&D institutions by mapping international scientific networks: the case of INESC Porto
No full textAlthough scientometric and bibliometric studies embrace a much wider perspective of the linkages/networks of R&D institutions than standard economic studies, to the best of our knowledge, these studies have not yet made use of scientometric tools to analyse the influence and impact of R&D institutions. Moreover, the international perspective has so far been neglected both in standard and bibliometric studies. Based on networks of 1239 foreign co-authorships and 13035 foreign citation linkages, we demonstrate that INESC Porto international influence has considerably expanded since 2003, a year that coincided with the implementation of an internal policy of granting monetary prizes to publications in scientific international journals. In terms of co-authorship, the network of INESC Porto more than duplicated (13 countries in the initial period to 27 in 2004-07). In terms of citations, INESC Porto’s network encompassed almost 40 countries during the whole period (1996-2007). Its more prolific units (optoelectronics, energy and multimedia) presented a rather distinct pattern both in terms of size and evolution of the corresponding network boundaries. The network size of foreign co-authorships was not much different between the three units by the beginning of the 2000s (around 10 countries) but it evolved quite distinctly. The most remarkable pattern was registered by the multimedia (UTM) unit, whose network size rose exponentially to 21 countries in 2004-07. This contrasted with the decline (down to 8 countries) of the energy (USE) unit. The citation network of the optoelectronic unit (UOSE) was by far the largest, until 2003, involving 34 distinct countries, which contrasted with the size of USE (12 countries) and UTM (1 country). But again, after 2003, the size of the citation network of USE and UTM converged spectacularly to that of UOSE’s, reaching in the last period 21 and 16, respectively. The influence of INESC Porto reaches all five continents, especially when we consider citation networks. Indeed, excluding the citations from authors affiliated in Portuguese institutions, those that most cite INESC Porto’s (and UOSE’s) works are affiliated in institutions located in China, the UK and the US. The scientific works produced by USE influences mostly authors affiliated in institutions located in India, China and Spain, whereas for UTM the corresponding countries are the US, Germany and Italy. We infer from the evidence analysed that not only did the boundaries of INESC Porto’s scientific network substantially enlarge in the period of analysis (1996-2007) but its ‘quality’ also evidenced a positive evolution, with authors affiliated in institutions located in the scientific frontier countries citing works of INESC Porto (and its units).Bibliometrics, Knowledge networks; R&D Institutions
Determinants of the international influence of a R&D organisation: a bibliometric approach
No full textTraditionally, studies on the influence and impact of knowledge-producing organisations have been addressed by means of strict economic analysis, stressing their economic impact to a local, regional or national extent. In the present study, an alternative methodology is put forward in order to evaluate the international scientific impact and influence of a knowledge-producing and -diffusing institution. We introduce a new methodology, based on scientometric and bibliometric tools, which complement traditional assessments by considering the influence of a R&D institution when looking at the scientific production undertaken and the recognition of its relevance by its international peer community. Focusing on the most prolific scientific areas of INESC Porto, and resorting to published scientific work recorded in the Science Citation Index (SCI), we show that INESC Porto has enlarged its international scientific network. The logit estimations demonstrate that the wide geographical influence of INESC Porto scientific research is a result not of its international positioning in terms of co-authorships, but rather a result of the quality of its scientific output.Impact and influence assessment methods; R&D Institutions; Bibliometrics, Scientometrics; knowledge network; INESC Porto
Assessing the influence of R&D institutions by mapping international scientific networks: the case of INESC Porto
No full textAlthough scientometric and bibliometric studies embrace a much wider perspective of the linkages/networks of R&D institutions than standard economic studies, to the best of our knowledge, these studies have not yet made use of scientometric tools to analyse the influence and impact of R&D institutions. Moreover, the international perspective has so far been neglected both in standard and bibliometric studies. Based on networks of 1239 foreign co-authorships and 13035 foreign citation linkages, we demonstrate that INESC Porto international influence has considerably expanded since 2003, a year that coincided with the implementation of an internal policy of granting monetary prizes to publications in scientific international journals. In terms of co-authorship, the network of INESC Porto more than duplicated (13 countries in the initial period to 27 in 2004-07). In terms of citations, INESC Porto’s network encompassed almost 40 countries during the whole period (1996-2007). Its more prolific units (optoelectronics, energy and multimedia) presented a rather distinct pattern both in terms of size and evolution of the corresponding network boundaries. The network size of foreign co-authorships was not much different between the three units by the beginning of the 2000s (around 10 countries) but it evolved quite distinctly. The most remarkable pattern was registered by the multimedia (UTM) unit, whose network size rose exponentially to 21 countries in 2004-07. This contrasted with the decline (down to 8 countries) of the energy (USE) unit. The citation network of the optoelectronic unit (UOSE) was by far the largest, until 2003, involving 34 distinct countries, which contrasted with the size of USE (12 countries) and UTM (1 country). But again, after 2003, the size of the citation network of USE and UTM converged spectacularly to that of UOSE’s, reaching in the last period 21 and 16, respectively. The influence of INESC Porto reaches all five continents, especially when we consider citation networks. Indeed, excluding the citations from authors affiliated in Portuguese institutions, those that most cite INESC Porto’s (and UOSE’s) works are affiliated in institutions located in China, the UK and the US. The scientific works produced by USE influences mostly authors affiliated in institutions located in India, China and Spain, whereas for UTM the corresponding countries are the US, Germany and Italy. We infer from the evidence analysed that not only did the boundaries of INESC Porto’s scientific network substantially enlarge in the period of analysis (1996-2007) but its ‘quality’ also evidenced a positive evolution, with authors affiliated in institutions located in the scientific frontier countries citing works of INESC Porto (and its units). Length: 64 pagesBibliometrics, Knowledge networks; R&D Institutions
The second Sandia Fracture Challenge: predictions of ductile failure under quasi-static and moderate-rate dynamic loading
No full text© 2016, The Author(s). Ductile failure of structural metals is relevant to a wide range of engineering scenarios. Computational methods are employed to anticipate the critical conditions of failure, yet they sometimes provide inaccurate and misleading predictions. Challenge scenarios, such as the one presented in the current work, provide an opportunity to assess the blind, quantitative predictive ability of simulation methods against a previously unseen failure problem. Rather than evaluate the predictions of a single simulation approach, the Sandia Fracture Challenge relies on numerous volunteer teams with expertise in computational mechanics to apply a broad range of computational methods, numerical algorithms, and constitutive models to the challenge. This exercise is intended to evaluate the state of health of technologies available for failure prediction. In the first Sandia Fracture Challenge, a wide range of issues were raised in ductile failure modeling, including a lack of consistency in failure models, the importance of shear calibration data, and difficulties in quantifying the uncertainty of prediction [see Boyce et al. (Int J Fract 186:5–68, 2014) for details of these observations]. This second Sandia Fracture Challenge investigated the ductile rupture of a Ti–6Al–4V sheet under both quasi-static and modest-rate dynamic loading (failure in (Formula presented.) 0.1 s). Like the previous challenge, the sheet had an unusual arrangement of notches and holes that added geometric complexity and fostered a competition between tensile- and shear-dominated failure modes. The teams were asked to predict the fracture path and quantitative far-field failure metrics such as the peak force and displacement to cause crack initiation. Fourteen teams contributed blind predictions, and the experimental outcomes were quantified in three independent test labs. Additional shortcomings were revealed in this second challenge such as inconsistency in the application of appropriate boundary conditions, need for a thermomechanical treatment of the heat generation in the dynamic loading condition, and further difficulties in model calibration based on limited real-world engineering data. As with the prior challenge, this work not only documents the ‘state-of-the-art’ in computational failure prediction of ductile tearing scenarios, but also provides a detailed dataset for non-blind assessment of alternative methods
Interactions between nuclear lamins and their binding partners in EDMD fibroblasts
No full textLamins are components of the nuclear lamina and are divided In A and B-types, which Interact with proteins of the inner nuclear membrane like emerin. Mutations in emerin (X-linked) and A-type lamins (Autosomal Dominant) has been linked to the Emery-Dreifuss Muscular Dystrophy (EDMD), which conduced to the hypothesis that these two proteins might interact in the nucleus. I examined the interaction between A and B-type lamins with emerin using a panel of deletion mutants of lamin Bl and full-length lamins A, C and B1 in a yeast two-hybrid assay, where emerin interacted with all lamins and the preferred region of interaction was the globular tail domain of lamin Bl. Ectopic expression of tagged proteins in human dermal fibroblasts confirmed that emerin remains attached to the inner nuclear envelope through its association with lamin 81, as aggregation of tagged A-type lamins did not miss localize endogenous emerin or lamin Bl. In addition, methanol-acetone fixation showed higher number of cells presenting characteristic morphological abnormalities called "honeycombs". A-type lamins and their associated protein emerin co- localized in these structures. Lamin Bl depletion from the honeycombs was accompanied by depletion of nuclear pore complexes. In the honeycombs, A- type lamins segregated from the B-type lamins, forming homo-filaments. On the other hand, AD-EDMD cell lines showed a characteristic pattern as a high sub-population of cells presented nesprin 1 (amino-terminal) in stress fibres co- localizing with a-S-Actin fibres, which was enhanced by growth inhibition induced by serum starvation. Re-stimulation of fibroblasts by normal serum concentrations increased the appearance of honeycombs by up to 2.5 fold in the AD-EDMD cell, lines. Late passage cultures of AD-EDMD entered a senescence state reminiscent of the induced quiescence state induced by serum starvation. Finally, differential allelic expression was evidenced using a specific set of ARMS-primers in the cell lines studied, indicative of transcript imbalance, and bioinformatics analysis demonstrated the presence of SNPs in the coding region of the wild type LMNA gene. The results of these study confirm that lamins interact with emerin and suggest that the interacting region is the tail domain of lamins; honeycomb structures might have a biological meaning in patient cells; other proteins might be involved in EDMD, like nesprins; and heterozygosis is presented with transcript imbalance, which might have a negative impact in the correct assembly of the nuclear lamina
