713 research outputs found
Towards the shell biorefinery: sustainable synthesis of the anticancer alkaloid Proximicin A from chitin
No full textA shell biorefinery would involve fractionation of crustacean shells and incorporation of the components into value-added products, particularly those that contain nitrogen. In a proof-of-concept study that validates this concept, the anticancer alkaloid proximicin A has been synthesized from the chitin-derived platform chemical 3-acetamido-5-acetylfuran (3A5AF). This study accentuates the leading role chitin is likely to play in the sustainable production of nitrogen-containing fine chemicals that are not directly attainable from lignocellulose.</p
The blind spots of secularization
No full textAccording to several international surveys Spain is among the western countries with the most negative views of Jews. While quantitative data on the topic accumulates, there is a significant lack of interpretative approaches that might explain the particular Spanish case. This paper presents the background, methodology and major results of a discussion group-based study on antisemitism, which was conducted in Spain in the autumn of 2009. The study identifies and locates in different socio-economic and ideological milieus the range of stereotypical discourses on Jews, Judaism and the Arab–Israeli conflict in Spain. Analysis of the group meetings shows that, despite growing secularization in Spanish society, the central explanatory variable for persisting and resurging antisemitism in this country is still religion in a broad cultural sense.N
Métricas de autor Alejandro Gómez Jaramillo
No full textInforme de las métricas de autor del Dr. Alejandro Gómez Jaramillo de las publicaciones indexadas en Google Académico cuyo objetivo es entregar un insumo para el fortalecimiento de las capacidades y potencialidades de los autores de la Universidad Santo Tomás en el posicionamiento y visibilidad de sus publicacionesReport of the author metrics Alejandro Gómez Jaramillo of the publications indexed in Google Scholar whose objective is to provide an input for the strengthening of the capacities and potentialities of the authors of the Santo Tomás University in the positioning and visibility of their publications.http://unidadinvestigacion.usta.edu.c
Bridging the gaps in Southern California: Multicultural spaces throughout the works of Alejandro Morales
No full textThe present paper proposes a detailed analysis of the fiction works by Chicano author Alejandro Morales, which map the historical and the potential evolution of the different L.A. settlements and communities, their history (of migration) and their often problematic interrelations. Morales’s narratives(1992-2014)reveal L.A.’s “complex utopian and dystopian ramifications” (Soja 2000:251)and its tendency towards stereotypization (Lie et. al. 2012). To that end,Morales goes far beyond his own familiar ‘space’ as a Latino in the U.S. crossing all types of borders(Spires 2014),making Latinos meet with Anglos, native Americans, African Americans, and Americans with Asian or European roots. At times, these ethnic groups seem to live in mono-ethnic geographies. Nonetheless, they also share the same spaces regardless of any inter/intra-ethnic group differences. Morales clearly seeks rapprochement through otherness and a sense of strangeness. Therefore, L.A. contains not only mono-ethnic but also transnational geographies, which allow Morales to conceive his own ‘geo-history’, where real and imagined space meet.
Works cited
Morales, Alejandro. Reto en el paraíso. México: Grijalbo, 1992. _______. The Brick People. Houston, Texas: Arte Público Press, 1992.
_______. The Captain of All These Men of Death. Arizona: Bilingual Press/Editorial Bilingüe, 2008.
_______. Little Nation & Other Stories. Transl. Adam Spires, Houston, Texas: Arte Público Press, 2014._______.
River of Angels.Houston Texas: Arte Público Press, University of Houston, 2014.
D’haen, Theo, Iannis Goerlant and Roger D. Sell. Major versus Minor? Languages and Literatures in a Globalized World. Amsterdam/Philadelphia: John Benjamins, 2015.
Gurpegui, José Antonio. Alejandro Morales: Fiction Past, Present, Future Perfect.Arizona: Bilingual Review/Press, 1996.
Lie, Nadia, Mandolessi, Silvana, Vandebosch, Dagmar. El juego con los estereotipos. La redefinición de la identidad hispánica en la literatura y el cine postnacionales. Brussels: Peter Lang, 2012.
Soja, Edward. Postmetropolis: Critical Studies of Cities and Regions. Oxford: Basil Blackwell, 2000.
Spires, Adam. “Alejandro Morales: Writing Chicano Space”, in Alejandro Morales, Little Nation & Other Stories. Transl. Adam Spires, Houston, Texas: Arte Público Press, 2014: vii-xxv.status: Publishe
Fronts of the Antarctic Circumpolar Current - GIS data
No full textProgress Code: completedStatement: The dates provided in temporal coverage correspond to the date of publication of the source paper.This line shapefile represents the following features of the Antarctic Circumpolar Current:<br/>Subtropical Front (STF);<br/>Subantarctic Front (SAF);<br/>Southern Antarctic Circumpolar Current Front (sACCf);<br/>Polar Front (PF);<br/>Southern Boundary of the Antarctic Circumpolar Current <br/><br/>as described in <br/><br/>Alejandro H. Orsi, Thomas Whitworth III, and Worth D. Nowlin Jr (1995) On the meridional extent and fronts of the Antarctic Circumpolar Current. Deep-Sea Research 42 (5), 641-673.<br/><br/>The shapefile was created from data provided by lead author Alejandro Orsi to the Australian Antarctic Data Centre in August 2001. The data in the files from Alejandro Orsi was also combined in a csv file. <br/>The data available for download includes the original data, the shapefile and the csv file
Genomic characterization of schizophrenia candidate gene regions
No full textSchizophrenia (SZ) is a severe mental disorder with a complex genetic etiology and a lifetime prevalence of ~0.55-1%. In this study, we extracted and analyzed data from 47 independent genomewide scans for linkage to SZ. The genome was partitioned into 22 schizophrenia candidate gene regions (SCRs) by applying three methods: single significant approach, disjoint approach, and smoothing method. For the single significant hit approach, an SCR was defined by the presence of a significant hit by extending 10 cM upstream and downstream of that hit. For the disjoint approach, we identified criteria-events based on clustering of hits within small regions by using a sliding window approach. For the smoothing method, we imputed a randomized range of p-values (0.001697≤p<1) for the genome scans without a suggestive or significant result at each 0.1 cM interval. We combined these p-values with the genome scan results using three methods: geometric mean method, Fisher’s method, and Stouffer’s method. We characterized each SCR by identifying the genes and genomic elements such as structural variations, regulatory elements, and functional noncoding RNAs. We also categorized the genes within SCRs. The total coverage of SCRs is 880 cM (739 Mb) with SCR sizes ranging from 18 cM to 87 cM. SCRs with multiple peaks were divided into smaller subregions. We developed a ranking system to identify and prioritize SZ candidate genes by assigning weights to each of the following criteria: (a) relative significance of a peak within an SCR, (b) annotated in SZ association studies and microarray analyses, and meta-analyses, (c) associated with phenotypes or diseases, and (d) located within or near other genetic elements. We identified functions/diseases and pathways that were most significantly associated with genes that had at least the same score or better than the top 10% of candidate genes after prioritization by utilizing the Ingenuity® Pathways Analysis (IPA). We generated an interactome for SZ based on the SZ candidate genes. We created a website (http://compgen.rutgers.edu/schiz) to disseminate information about our SCRs. Our procedure, which provides a novel approach to identify and prioritize candidate gene regions and genomic elements, is applicable to other complex diseases.Ph. D.Includes bibliographical referencesby Alejandro Q. Nato, Jr
Alejandro Groizard y su análisis del Código penal de 1870
No full textGrado en Derecho y Grado en Administración y Dirección de EmpresasEste Trabajo de Fin de Grado presenta un intenso y exhaustivo estudio sobre la vida de D. Alejandro Groizard y Gómez de la Serna, reconocida personalidad del S. XIX, que dedicó su vida al servicio público, ejerciendo en numerosas ocasiones cargos como el de Ministro, Senador, Diputado, Abogado, Diplomático y Jurista. En concreto, nos centraremos en su dimensión como autor jurídico, y en su aportación a la labor codificadora en el ámbito penal, formando parte de la Comisión Legislativa encargada de elaborar el Código Penal de 1870, que posteriormente completaría con su obra más elogiada «Comentarios al Código penal de 1870», la cual fue objeto de tres ediciones y contribuyó de forma decisiva a la consolidación de los principios que se defendían en la nueva Constitución de 1869.This end-of-grade project, tries to approach an intensive and exhaustive analysis of the life of Mr. Alejandro Groizard and Gómez de la Serna, the recognized personality of the 19th century, who dedicated his life to the public service, exercising in several times positions like Minister, Senator, Deputy, Lawyer, Diplomat and Jurist. Specifically, we will focus on his dimension as a legal author, and in his contribution to the Criminal Codification work, forming part of the Legislative Commission responsible for drafting the Penal Code of 1870, which he will later complete with his most praised work «Comments to the Penal Code of 1870», which was the subject of three editions and contributed to the consolidation of the principles that were defended in the new Constitution of 1869
Linterna magica de la constitucion. Carta á los Amantes de la Pátria
No full textLetter detailing how the author came upon an exposition entitled 'esposicion que hace un honrado español', concerning Spanish politics and the constitutions, which he has reproduced. Dated 24 August 182
Conditionality and debt relief
No full textSix years into the debt crisis, questions about the relevance of policy measures to alleviate the crisis still abound. Conditionality by international financial institutions and rescheduling by commercial creditors have been dismissed in favor of debt reduction as strategies for restoring the creditworthiness of heavily indebted countries. This paper argues that the combination of conditionality and new private money - if properly interpreted and correctly implemented - should not be dismissed too lightly. The paper contends that liquidity (the availability of current resources) in the debtor country is probably as important an incentive for a country to invest and adjust as having a small enough debt stock outstanding. Debt reduction alone, is not as efficient as simultaneously providing liquidity and debt reduction if liquidity were available. The combination of new money and conditionality will work if the debt stock is small enough and enough new money is available.Environmental Economics&Policies,Economic Theory&Research,Strategic Debt Management,Financial Intermediation,Housing Finance
The internal and external flow fields of a structured porous coated cylinder and implications on flow-induced noise
No full textPorous coated cylinders have been shown to reduce the vortex shedding tone and broadband noise of a bare cylinder placed in uniform flow within specific Reynolds number regimes. The processes by which the vortex shedding and thus tone suppression take place are still uncertain despite numerous numerical and experimental studies. It is understood that adding a porous medium to a bare cylinder will have an influence on the Reynolds number of cylinder, yet the increase of outer diameter alone and the influences of surface roughness are insufficient to explain the changes in the shedding tone magnitude and frequency that are observed by many. Investigating the internal flow field of a porous coated cylinder could lead to a deeper understanding of the flow processes that result in the tonal noise reduction. This has not been achieved to date, as commonly used materials such as metal foam and polyurethane possess randomized porous structures, which make investigating the internal flow field nearly impossible without affecting the structure itself. This paper presents a preliminary analysis of the internal and external flow fields of two structured porous coated cylinders. The cylinders were manufactured using solid transparent materials that possess direct lines of sight through the pores in the axial and spanwise directions. Such structured porous coated cylinders have been previously successful in reducing the typical vortex shedding tone. Tomographic and 2-D planar Particle Image Velocimetry (PIV) were used in a water-tunnel facility to visualize the internal and external flow fields. To date only the 2-D planar PIV results have been post-processed that reveal differences in the wake for the two different cylinder types such as recirculation of flow around the pores. Vorticity flow structures are observed to vary along the cylinder span in the same pattern as the porous structure and streamlines at the windward cylinder side reveal the entry of flow into the porous medium.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Aircraft Noise and Climate EffectsWind Energ
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