1,728,435 research outputs found
The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation
Full text linkBackground. 
The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community.

Description. 
SADI – Semantic Automated Discovery and Integration – is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services “stack”, SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers.

Conclusions.
SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behavior we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services can be explored in a manner very similar to data housed in static triple-stores, thus facilitating the intersection of Web services and Semantic Web technologies
Letter from Munir M. Sadi, December 4, 1967
No full textLetter from Munir M. Sadi to Fayez Sayegh, December 4, 1967, regarding his appearance on the David Susskind show and the Arab-Israeli conflict
SADI-S WITH RIGHT GASTRIC ARTERY LIGATION: TECHNICAL SYSTEMATIZATION AND EARLY RESULTS
No full textABSTRACT Background: Bariatric surgery is performed all over the world with close to 500.000 procedures per year. The most performed techniques are Roux-en-Y gastric bypass and sleeve gastrectomy. Despite this data, the most effective procedure, biliopancreatic diversion with or without duodenal switch, represents only no more than 1.5% of the procedures. Technical complexity, morbidity, mortality, and severe nutritional adverse effects related to the procedure are the main fears that prevent most universal acceptance. Aim: To explain the technical aspects and the benefits of the SADI-S with right gastric artery ligation as an effective simplification from the original duodenal switch. Methods: Were included all patients undergoing this procedure from the November 2014 to May 2016, describing and analysing aspects of this technique, the systematization and early complications associated with the procedure. Results: A series of 67 patients were operated; 46 were women (68.7%); mean age of the group was 44 years old (33-56); and an average BMI of 53.5 kg/m2 (50-63.5). Surgical time was 115 min (80-180). A total of five patients (7.5%) had any complication and two (2.9%) had to be reoperated. There were two patients with leak, one at the duodenal stump and other at the esophagogastric angle. There was no mortality. Patients stayed at the hospital a median of 2.5 days (1-25). Conclusions: SADI-S with right gastric artery ligation is a safe procedure with few preliminary complications. The technical variations introduced to the classical duodenal switch are reproducible and may allow this procedure to be more popular. All the complications in this series were not related to the ligation of the right gastric artery.</div
Initial experience with laparoscopic revisional single anastomosis duodeno-ileal bypass (SADI-S) after failed sleeve gastrectomy
Full text linkIntroduction: Laparoscopic sleeve gastrectomy (SG) is currently the most commonly performed bariatric operation, but re-do surgery may be necessary in up to half of the patients. Single anastomosis duodeno-ileal bypass (SADI-S) is quickly gaining recognition as a revisional procedure after failed SG. Aim: To discuss the surgical technique and analyze initial outcomes after introduction of SADI-S after SG with 1-year follow-up. Material and methods: This is a retrospective cohort study of consecutive patients who underwent re-do bariatric surgery – revisional SADI-S – in 2021 at a secondary referral public hospital. All patients’ follow-up was completed 1 year after. Results: 14 consecutive patients, 6 (43%) males and 8 females, were included. Median maximal body mass index (BMI) was 52.29 (47.96–77.16) kg/m2, BMI before SADI-S was 43.09 (41.64–48.99) kg/m2. No perioperative morbidity was recorded. Four (28%) patients reported recurrent abdominal crampy pain and diarrhea that required dietary advisement and pharmacological therapy in the postoperative period. No reoperations, mortality or readmissions were recorded during 1-year follow-up. SADI-S was associated with further weight loss, resulting in median BMI of 37.55 (36.29–39.43) kg/m2 1 year after SADI-S. Observed additional percentage total weight loss (%TWL) 1 year after SADI-S was 18.65% (17.25–21.89%), while additional percentage excess body mass index loss (%EBMIL)
was 35.88% (29.18–41.92%). There was 1 case of diabetes mellitus type 2 remission and improvement in glycemic control in 1 patient. 4/6 patients (66.67%) had improvement in control of hypertension. Conclusions: SADI-S is promising re-do surgery after SG with low postoperative morbidity. Additional %TWL 1 year after SADI-S is ~19%, while additional %EBMIL is ~36%, with significant improvement of obesity-related comorbidities
Executing SADI services in Galaxy
Full text linkBackground: In recent years Galaxy has become a popular workflow management system in bioinformatics, due to its ease of installation, use and extension. The availability of Semantic Web-oriented tools in Galaxy, however, is limited. This is also the case for Semantic Web Services such as those provided by the SADI project, i.e. services that consume and produce RDF. Here we present SADI-Galaxy, a tool generator that deploys selected SADI Services as typical Galaxy tools.
Results: SADI-Galaxy is a Galaxy tool generator: through SADI-Galaxy, any SADI-compliant service becomes a Galaxy tool that can participate in other out-standing features of Galaxy such as data storage, history, workflow creation, and publication. Galaxy can also be used to execute and combine SADI services as it does with other Galaxy tools. Finally, we have semi-automated the packing and unpacking of data into RDF such that other Galaxy tools can easily be combined with SADI services, plugging the rich SADI Semantic Web Service environment into the popular Galaxy ecosystem.
Conclusions: SADI-Galaxy bridges the gap between Galaxy, an easy to use but "static" workflow system with a wide user-base, and SADI, a sophisticated, semantic, discovery-based framework for Web Services, thus benefiting both user communities.Mikel Egana Aranguren is funded by the Marie Curie Cofund programme (FP7) of the European Union and the Genomic Resources Group of the University of Basque Country. Alejandro Rodriguez Gonzalez and Mark D. Wilkinson are funded by the Isaac Peral Programme of the CBGP-UPM
Sadi Divanı
No full textUralçin, Sema, Sadi Divanı, Yüksek Lisans Tezi, Danışman: Prof. Dr. İsmail Hakkı Aksoyak, 247 s. ÖZET: Bu çalışmada 17.yüzyılda yaşamış olan Sadi Divanı'nı araştırmacıların hizmetine sunmayı hedefledik. Şairin hayatı ve eserinin önemli olması bizi artık yitirilmekte olan bir dünya görüşünün sanat anlayışında son izleri taşıyan bu eseri çalışmaya sevk etmiştir. Çalışma, devir-şahsiyet-eser ekseninde ele alınmıştır. Divan metni, transkripsiyon harfleriyle yeniden yazılmıştır. Divan'ın tıpkıbasımı ise "Ekler" bölümünde verilmiştir.Uralçin, Sema, The Divan of Sadi, Master’sThesis, Advisor: Prof. Dr. İsmail Hakkı Aksoyak, 247 p. ABSTRACT: Inthisstudy, weaimedtoservethepeoplewhosearchthe divan of Sadi, lived in 17 thcentury. Thatthere is importantaboutpoetand his works, directed us tostudythiswork of art which is a worldopinionstartedtoloseit'svalue. Divan has beentakencharge of period, personalityandwork. Thetext of Divan has beenrewrotewiththetranscripcionalphabet. Thefacsimile of Divan is given in additionalperiod
Editorial: South Asian Dance Intersections
Full text linkWelcome to the inaugural issue of SADI—South Asian Dance Intersections—a progressive, scholarly, blind peer-reviewed, open-access online journal. SADI was conceived during the pandemic as a transnational feminist project. It proposes a field-defining modality of looking at scholarship around South Asian dance studies emerging within the field across values, theories, and practices. It seeks to carry to newer and larger audiences, a unique blend of high-quality research in scholarly, theoretical, textual, choreographic, contemporary, social justice, and community-oriented, interdisciplinary, and intersectional writing. SADI explores the ecosphere of South Asian dance activities, celebrating plural practices, diversity, and richness, while challenging incongruencies
- …
