1,721,107 research outputs found
Surface dysgraphia in a regular orthography: apostrophe use by an Italian writer.
No full textThe dual-route model of writing assumes two basic procedures involved in writing: lexical and non-lexical. The lexical
route is fundamental in opaque orthographies such as English; from its impairment surface dysgraphia arises.
Evidence for the role of a lexical route in transparent languages such as Italian, which have a regular orthography, has
been more limited. We report a case study of ES, an Italian patient suffering from degenerative brain disease, who
presented with a selective disorder of writing. He showed the unusual phenomenon of inserting an apostrophe
inappropriately in the spellings of words. Neuropsychological evaluation provided evidence of loss of orthographic
meaning of the apostrophe and a pattern of writing performance consistent with surface dysgraphia. There was also
evidence of an accompanying surface dyslexia. We conclude that examination of apostrophe use provides a valuable
means of detecting surface dysgraphia in the Italian language. The findings point to the need for cognitive models
of writing to account for ‘‘dumb symbols’’ of language such as the apostrophe. This unique case provides a further
example of the variety of clinical presentations of focal cerebral degeneration
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons
Get PDFFrontotemporal lobar degeneration (FTLD) is the one of the most frequent neurodegenerative disorders characterized by behavioral and executive impairment, language disorders and motor dysfunction. Hereditary forms of FTLD are frequently reported and about 20-30% of cases exhibit an autosomal dominant transmission. Microtubule associate protein tau (MAPT) gene mutations are associated with early onset FTLD. Here we have identified a new MAPT mutation on exon 10 that alters both the protein function and the RNA alternative splicing. Biochemical and neuropathological studies indicate a high pathogenicity of this new MAPT mutation. Moreover induced neurons transdifferentiated from patient skin-derived fibroblasts and carrying the new MAPT mutation express both 3R and 4R tau isoforms differently from those obtained from embryonic fibroblasts which express only 3R tau isoform indicating that they are not mature neurons
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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