1,720,966 research outputs found
Dilated Minute Chambers in Laryngeal Vocal Fold Polyps: Histopathological and Ultrastructural Features
No full textSaygi, Halil Ibrahim/0000-0001-8736-3282; yener, h murat/0000-0002-0932-2773; Tanriover, Ozlem/0000-0003-0251-3451; comunoglu, nil/0000-0002-2319-1757In Reinke's space of human vocal fold, type III collagen forms a three dimensional network and this contains numerous minute chambers in between these fibers. These compartments are occupied by glycosaminoglycans and glycoproteins. In laryngeal fold lesions, such as Reinke's edema and vocal fold polyps, proteoglycan (PG)/hyaluronic acid (HA) components of extracellular matrix increased. We investigated the size and quantity of the minute chambers within Reinke's space, filled with PG/HA with the aid of transmission electron microscopy. Eight vocal fold polyps and 10 mucosal biopsies (as control group) were all evaluated by light microscopy and electron microscopy. We detected that PG/HA in extracellular matrix had been increased in vocal fold lesions when compared with control group, by Alcian Blue-pH 2.5 stain. The mean volume of the chambers in Reinke's space of normal larynx was measured as 0.040233 /mu m(2) whereas the mean volume of these chambers in vocal fold polyps was measured as 6.420221 mu m(2) The difference between the volumes of these chambers in vocal fold polyps and in control group was statistically significant (P = 0.001). Within these chambers PG/HA were found and PG/HA filling these chambers were increased in vocal fold polyps. We think proteoglycan and glycosaminoglycans, especially HA, play an important role in determining biochemical properties of vocal fold lesions
The Investigation of STAT3 protein expression changes in rat kidney injury model induced by puromycin aminonucleoside application
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The Effects of Antifreeze Proteins I and III Supplemented Medium on Cryopreserved Rat Ovaries in Differen Durations
No full textCryopreservation techniques achieved by optimization of the composition and concentration of cryoprotectants not only reduce cryoinjury to ovarian tissue but also enhance survival. Anti-Freeze Proteins (AFPs) have been acknowledged to have positive effects on the survival of oocytes, embryos and ovaries during cryopreservation. AFPs drop the freezing point beneath the balance point of melting by binding ice crystals; restricting their expansion and recrystallization. This study aimed to investigate the protective effects of AFP I and III separately or in combination on the vitrification and warming procedures of ovarian tissues which were vitrified for one week and one month. Ovaries were obtained from rats and randomly assigned to four groups according to the AFP supplements in the media used during freeze/warm procedures: 1) control group (medium without AFP); 2) AFP I; 3) AFP III; 4) AFP I + AFP III groups.The groups were further organized according to the duration of vitrification, 1 week or 1 month. Ovaries were evaluated morphologically by a grading system, TUNEL assay and by transmission electron microscopy. AFP supplementation decreased apoptosis and follicular damage. Supplementation of AFP type I and type III has cryoprotective roles in ovaries which were vitrified for 1 week and 1 month. Additionally, AFP I+AFP III supplementation were shown to have more protection in long term
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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