1,721,287 research outputs found
Krabbe disease: a case of late-onset form. Pucci E, Bruscella S, Rognone E, Bastianello S, Cristina S, Sandrini G.
No full textThe Italian Consensus Conference on Pain in Neurorehabilitation
Full text linkPain is frequent in several neurological conditions, such as stroke, Parkinson’s disease, multiple sclerosis, diabetic neuropathy, but it is often underestimated and therefore untreated or not successfully treated. Pain reduces quality of life, it may be the cause of adaptive disorders (such as anxiety and depression) and, in patients undergoing rehabilitation, it may negatively impact rehabilitation procedures and hamper the outcome. Unfortunately, there are no significant data regarding the impact of pain in neurorehabilitation patients and what would be the impact of an appropriate pain treatment on rehabilitation outcome. Accordingly, there are no guidelines providing indications on how to treat pain in patients with pain during rehabilitation treatment and thereafter. Given this background, and to comply with the Italian law 38 released on 2010 by the Italian Ministry of Health to guarantee adequate care and treatment of patients with pain both in hospital and in primary care, the Italian Society for Neurological Rehabilitation (SIRN) along with the Italian Society for Physical and Rehabilitative Medicine (SIMFER), promoted a work-in-progress platform, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPNR)
Il dolore in neuroriabilitazione
No full textIl dolore rappresenta un problema comune in neuroriabilitazione, sia perchè esso può costituire il target della riabilitazione stessa, sia perchè può condizionare negativamente l'outcome del percorso neuroriabilitativo. Il capitolo tratta fisiologia e fisiopatologia del dolore nocicettivo e neuropatico, strumenti di valutazione del dolore e per la diagnosi differenziale tra dolore nocicettivo e neuropatico (test di screening, algoritmo NeuPSIG), cenni di terapia del dolore ed una rassegna delle principali condizioni di dolore che si incontrano in neuroriabilitazione
Metodologia di studio dei fattori psicologici nelle cefalee di tipo tensivo: razionale e strumenti operativi
No full textEffects of Neuromodulation on Gait
No full textIn the last decades, non-invasive brain stimulation (NIBS) has evolved to become a valuable tool in both basic and clinical neuroscience. Various methods of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (TES) have been widely used for diagnostic, prognostic and even therapeutic applications in a broad range of neurological and psychiatric disorders. The rationale for using NIBS techniques lies in the possibility to modulate, in a targeted manner, the activity of different cerebral and cerebellar cortical regions, as well as the functional connections between these areas and distant brain regions also including subcortical structures. The neural circuitry involved in the different aspects of gait control is very complex and includes, along with the basal ganglia-cortical loops, the cerebellum and structures of the brainstem and the spinal cord. This is why different approaches of NIBS have been suggested for treatment of gait disorders in a variety of neurological disorders including Parkinson’s disease, stroke, cerebellar ataxia, multiple sclerosis, cerebral palsy and spinal cord injury. This review will collate the available knowledge on the physiology of gait and balance control, focusing on the ways in which the use of NIBS may contribute to the understanding and treatment of gait disorders
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A Comprehensive Method for Computing Suspension Elasto-kinematics With Non-linear Compliance
Full text linkSince flexible bushings are used as the interface between the suspension arms and the chassis, the extra degrees of freedom make the design process a complex task. While the use of a multi-body model is common practice in the industry, a dedicated computational tool can be more practical and straightforward, especially when undertaking the design of a new suspension concept from the ground up. This paper presents a quasi-static method for calculating suspension compliance under the action of forces and moments, enabling real-time simulations. The algorithm proposed in this paper was devised with a threefold purpose: integrating elasto-kinematics into the kinematic design tool previously created by the authors, integrating real-time vehicle dynamics simulation, and overcoming the limitations of the traditional approach based on the superposition principle. Finally, a comparison of the proposed model with one based on the lookup-table and superposition principle is presented
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